Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IRX4
  • Mouse genes Irx4
  • Rat genes Irx4
  • Zfish genes irx4a,irx4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Irx4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IRX4	IPI	UniProtKB:P78424	Human	PMID:32296183
Biological Process	GO:0048561	establishment of animal organ orientation	Irx4	IEP		Rat	PMID:10882515|RGD:1582291
Biological Process	GO:0007507	heart development	Irx4	IMP	MGI:MGI:2180895	Mouse	PMID:11238910
Biological Process	GO:0042461	photoreceptor cell development	irx4a	IMP	ZFIN:ZDB-MRPHLNO-100416-8	Zfish	PMID:19111617
Biological Process	GO:0048923	posterior lateral line neuromast hair cell differentiation	irx4a	IMP	ZFIN:ZDB-MRPHLNO-100416-8	Zfish	PMID:19111617
Biological Process	GO:0048924	posterior lateral line neuromast mantle cell differentiation	irx4a	IMP	ZFIN:ZDB-MRPHLNO-100416-8	Zfish	PMID:19111617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern