Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IST1
  • Mouse genes Ist1
  • Rat genes Ist1
  • Zfish genes ist1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ist1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	IST1	HDA		Human	PMID:25468996
Molecular Function	GO:0090541	MIT domain binding	IST1	IPI	UniProtKB:O75351	Human	PMID:19129479
Molecular Function	GO:0090541	MIT domain binding	IST1	IPI	UniProtKB:Q9UN37	Human	PMID:19129479
Molecular Function	GO:0090541	MIT domain binding	IST1	IPI	UniProtKB:Q9UN37	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P13798	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P54253	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q7LBR1	Human	PMID:19129479
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9H9H4	Human	PMID:19129479
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9HD42	Human	PMID:19129479
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9NP79	Human	PMID:19129479
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:O43633	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P52917	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P69771	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q06263	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q7LBR1	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9HD42	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9NP79	Human	PMID:19129480
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q7LBR1	Human	PMID:19525971
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q8N0X7	Human	PMID:20719964
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9Y6W3	Human	PMID:20849418
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q8WV92	Human	PMID:23045692
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9Y6W3	Human	PMID:24953135
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P13798	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q7Z479	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9UMX0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:Q9UBP0	Human	PMID:26040712
Molecular Function	GO:0005515	protein binding	IST1	IPI	UniProtKB:P13798	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Ist1	IPI	UniProtKB:Q9BY43	Mouse	MGI:MGI:5567910|PMID:18209100
Molecular Function	GO:0019904	protein domain specific binding	IST1	IPI	UniProtKB:Q9UBP0	Human	PMID:20719964
Molecular Function	GO:0019904	protein domain specific binding	IST1	IPI	UniProtKB:Q9Y6W3	Human	PMID:20849418
Molecular Function	GO:0044877	protein-containing complex binding	IST1	IDA		Human	PMID:19129479
Cellular Component	GO:0005813	centrosome	IST1	IDA		Human	PMID:19129479
Cellular Component	GO:0005813	centrosome	IST1	IDA		Human	PMID:20719964
Cellular Component	GO:0000785	chromatin	IST1	IDA		Human	PMID:28242692
Cellular Component	GO:0005829	cytosol	IST1	IDA		Human	PMID:19129480
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IST1	IDA		Human	PMID:10942595
Cellular Component	GO:0070062	extracellular exosome	IST1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	IST1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	IST1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	IST1	HDA		Human	PMID:23533145
Cellular Component	GO:0090543	Flemming body	IST1	IDA		Human	PMID:19129479
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	IST1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030496	midbody	IST1	IDA		Human	PMID:19129479
Cellular Component	GO:0030496	midbody	IST1	IDA		Human	PMID:20719964
Biological Process	GO:0009838	abscission	IST1	IDA		Human	PMID:19129479
Biological Process	GO:0009838	abscission	IST1	IDA		Human	PMID:19129480
Biological Process	GO:0009838	abscission	IST1	IMP		Human	PMID:19525971
Biological Process	GO:0048675	axon extension	ist1	IMP	ZFIN:ZDB-MRPHLNO-131014-1	Zfish	PMID:23897888
Biological Process	GO:0051301	cell division	IST1	IMP		Human	PMID:19129479
Biological Process	GO:0051301	cell division	IST1	IMP		Human	PMID:19129480
Biological Process	GO:0051301	cell division	IST1	IMP		Human	PMID:20719964
Biological Process	GO:0048668	collateral sprouting	Ist1	IGI	MGI:MGI:2139806	Mouse	PMID:22619377
Biological Process	GO:0061640	cytoskeleton-dependent cytokinesis	IST1	IMP		Human	PMID:19525971
Biological Process	GO:0007032	endosome organization	ist1	IMP	ZFIN:ZDB-MRPHLNO-131014-1	Zfish	PMID:23897888
Biological Process	GO:0045184	establishment of protein localization	IST1	IMP		Human	PMID:23015756
Biological Process	GO:0048672	positive regulation of collateral sprouting	Ist1	IGI	MGI:MGI:2139806	Mouse	PMID:22619377
Biological Process	GO:0045862	positive regulation of proteolysis	IST1	IDA		Human	PMID:20849418
Biological Process	GO:0008104	protein localization	IST1	IMP		Human	PMID:20719964
Biological Process	GO:0046745	viral capsid secondary envelopment	IST1	IDA		Human	PMID:19129479
Biological Process	GO:0019076	viral release from host cell	IST1	IDA		Human	PMID:19129479

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern