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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Itga5

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itga5
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0050839cell adhesion molecule bindingItga5IDARatPMID:12821041|RGD:1300196
Molecular FunctionGO:0005154epidermal growth factor receptor bindingItga5IPIRGD:2543RatPMID:21349584|RGD:5131469
Molecular FunctionGO:0001968fibronectin bindingitga5IGIZFIN:ZDB-GENE-000426-1,ZFIN:ZDB-GENE-060803-2ZfishPMID:19641014
Molecular FunctionGO:0005178integrin bindingItga5IPIPR:Q9Z0T9MousePMID:8601592
Molecular FunctionGO:0005178integrin bindingItga5IPIPR:O54890MousePMID:8601592
Molecular FunctionGO:0005178integrin bindingItga5IPIPR:O70309MousePMID:8601592
Molecular FunctionGO:0005178integrin bindingItga5IPIPR:P09055MousePMID:8601592
Molecular FunctionGO:0005178integrin bindingItga5IPIRGD:2927RatPMID:18167060|RGD:2314623
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P48745HumanPMID:12695522
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:12724312
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P35555HumanPMID:12807887
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P78536HumanPMID:14970227
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P49747HumanPMID:16051604
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:16099422
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P35555HumanPMID:17158881
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05106,UniProtKB:P21246HumanPMID:19141530
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:O14786HumanPMID:19175293
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P97333HumanPMID:19175293
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:21947080
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:Q9H0F6HumanPMID:21947080
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:22178926
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:22451694
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P17813HumanPMID:22940691
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:Q99828HumanPMID:24011356
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556HumanPMID:30021884
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556,UniProtKB:P29965HumanPMID:31331973
Molecular FunctionGO:0005515protein bindingITGA5IPIUniProtKB:P05556,UniProtKB:P0DTC2,UniProtKB:Q9BYF1HumanPMID:33102950
Molecular FunctionGO:0005515protein bindingItga5IPIUniProtKB:P23242MouseMGI:MGI:5314545|PMID:22331870
Molecular FunctionGO:0005515protein bindingItga5IPIUniProtKB:P68254MouseMGI:MGI:5644009|PMID:24163432
Molecular FunctionGO:0005515protein bindingItga5IPIPR:P09055MousePMID:12904471
Molecular FunctionGO:0005515protein bindingItga5IPIPR:O54890MousePMID:12867986
Molecular FunctionGO:0005515protein bindingItga5IPIPR:P11276MousePMID:12867986
Molecular FunctionGO:0005515protein bindingItga5IPIUniProtKB:P48509MousePMID:17716972
Molecular FunctionGO:0046982protein heterodimerization activityitga5IPIUniProtKB:Q3YAA1ZfishPMID:19641014
Molecular FunctionGO:0046982protein heterodimerization activityitga5IPIUniProtKB:Q3YAA1ZfishPMID:19747169
Molecular FunctionGO:0046982protein heterodimerization activityitga5IPIUniProtKB:Q3YAA0ZfishPMID:19747169
Cellular ComponentGO:0009986cell surfaceITGA5IDAHumanPMID:17158881
Cellular ComponentGO:0009986cell surfaceITGA5HDAHumanPMID:19581412
Cellular ComponentGO:0009986cell surfaceITGA5IDAHumanPMID:20563599
Cellular ComponentGO:0009986cell surfaceITGA5IDAHumanPMID:23154389
Cellular ComponentGO:0009986cell surfaceITGA5HDAHumanPMID:23658023
Cellular ComponentGO:0009986cell surfaceItga5IDAMouseMGI:MGI:5469937|PMID:23023225
Cellular ComponentGO:0009986cell surfaceItga5IDAMousePMID:8306881
Cellular ComponentGO:0005911cell-cell junctionITGA5IDAHumanPMID:14970227
Cellular ComponentGO:0005737cytoplasmItga5IDARatPMID:12821041|RGD:1300196
Cellular ComponentGO:0031410cytoplasmic vesicleItga5IDAMouseMGI:MGI:5605959|PMID:12189152
Cellular ComponentGO:0005783endoplasmic reticulumItga5IDAMouseMGI:MGI:5605959|PMID:12189152
Cellular ComponentGO:0009897external side of plasma membraneItga5IDAMousePMID:8557754
Cellular ComponentGO:0009897external side of plasma membraneItga5IDAMousePMID:9553049
Cellular ComponentGO:0005925focal adhesionITGA5IDAHumanPMID:14970227
Cellular ComponentGO:0005925focal adhesionITGA5IDAHumanPMID:17158881
Cellular ComponentGO:0005925focal adhesionITGA5HDAHumanPMID:21423176
Cellular ComponentGO:0005925focal adhesionITGA5IDAHumanPMID:29162887
Cellular ComponentGO:0098978glutamatergic synapseItga5IDARatPMID:27518800|RGD:155230752
Cellular ComponentGO:0005794Golgi apparatusItga5IDAMouseMGI:MGI:5605959|PMID:12189152
Cellular ComponentGO:0034674integrin alpha5-beta1 complexITGA5IPIHumanPMID:22451694
Cellular ComponentGO:0034674integrin alpha5-beta1 complexITGA5IDAHumanPMID:31331973
Cellular ComponentGO:0034674integrin alpha5-beta1 complexITGA5IDAHumanPMID:33102950
Cellular ComponentGO:0008305integrin complexItga5IDARatPMID:12821041|RGD:1300196
Cellular ComponentGO:0005886plasma membraneITGA5IDAHumanPMID:19141530
Cellular ComponentGO:0005886plasma membraneItga5IDAMouseMGI:MGI:5605959|PMID:12189152
Cellular ComponentGO:0045211postsynaptic membraneItga5IDARatPMID:27518800|RGD:155230752
Cellular ComponentGO:0032587ruffle membraneITGA5IDAHumanPMID:14970227
Cellular ComponentGO:0045202synapseItga5IDAMousePMID:12904471
Biological ProcessGO:0030325adrenal gland developmentitga5IMPZFIN:ZDB-MRPHLNO-050712-1,ZFIN:ZDB-MRPHLNO-050713-1ZfishPMID:22937010
Biological ProcessGO:0003401axis elongationitga5IGIZFIN:ZDB-GENO-221208-11ZfishPMID:35732225
Biological ProcessGO:0090245axis elongation involved in somitogenesisitga5IMPZFIN:ZDB-MRPHLNO-050620-1,ZFIN:ZDB-MRPHLNO-120823-8ZfishPMID:23810535
Biological ProcessGO:0051216cartilage developmentitga5IMPZFIN:ZDB-GENO-221208-8ZfishPMID:35732225
Biological ProcessGO:0051216cartilage developmentitga5IGIZFIN:ZDB-GENO-221208-9ZfishPMID:35732225
Biological ProcessGO:0051216cartilage developmentitga5IGIZFIN:ZDB-GENO-221208-11ZfishPMID:35732225
Biological ProcessGO:0051216cartilage developmentitga5IGIZFIN:ZDB-GENO-221208-10ZfishPMID:35732225
Biological ProcessGO:0023035CD40 signaling pathwayITGA5IDAHumanPMID:31331973
Biological ProcessGO:0007155cell adhesionITGA5IDAHumanPMID:19703720
Biological ProcessGO:0007155cell adhesionItga5IDARatPMID:12821041|RGD:1300196
Biological ProcessGO:0033627cell adhesion mediated by integrinITGA5IDAHumanPMID:12807887
Biological ProcessGO:0033627cell adhesion mediated by integrinITGA5IDAHumanPMID:17158881
Biological ProcessGO:0002042cell migration involved in sprouting angiogenesisitga5IMPZFIN:ZDB-MRPHLNO-050712-1,ZFIN:ZDB-MRPHLNO-050713-1ZfishPMID:22937010
Biological ProcessGO:0033631cell-cell adhesion mediated by integrinItga5IMPMousePMID:8557754
Biological ProcessGO:0031589cell-substrate adhesionITGA5IMPHumanPMID:19933311
Biological ProcessGO:0007044cell-substrate junction assemblyItga5IDAMousePMID:12867986
Biological ProcessGO:0048703embryonic viscerocranium morphogenesisitga5IMPZFIN:ZDB-GENO-120120-1ZfishPMID:25810090
Biological ProcessGO:0048703embryonic viscerocranium morphogenesisitga5IGIZFIN:ZDB-GENO-150821-4ZfishPMID:25810090
Biological ProcessGO:0060956endocardial cell differentiationitga5IGIZFIN:ZDB-GENO-220222-11ZfishPMID:32628938
Biological ProcessGO:0001706endoderm formationitga5IMPZFIN:ZDB-GENO-221208-4ZfishPMID:35732225
Biological ProcessGO:0001706endoderm formationitga5IGIZFIN:ZDB-GENO-221208-5ZfishPMID:35732225
Biological ProcessGO:0001706endoderm formationitga5IGIZFIN:ZDB-GENO-221208-14ZfishPMID:35732225
Biological ProcessGO:0035987endodermal cell differentiationITGA5IMPHumanPMID:23154389
Biological ProcessGO:0085029extracellular matrix assemblyitga5IMPZFIN:ZDB-GENO-100512-3ZfishPMID:19641014
Biological ProcessGO:0085029extracellular matrix assemblyitga5IMPZfishPMID:19641014
Biological ProcessGO:0007565female pregnancyItga5IEPRatPMID:17715430|RGD:13593537
Biological ProcessGO:0021782glial cell developmentitga5IMPZFIN:ZDB-CRISPR-191009-71,ZFIN:ZDB-CRISPR-191009-72ZfishPMID:30924555
Biological ProcessGO:0007157heterophilic cell-cell adhesion via plasma membrane cell adhesion moleculesItga5IMPMousePMID:8557754
Biological ProcessGO:0034113heterotypic cell-cell adhesionITGA5IMPHumanPMID:20563599
Biological ProcessGO:0007229integrin-mediated signaling pathwayITGA5IDAHumanPMID:31331973
Biological ProcessGO:0007229integrin-mediated signaling pathwayItga5IDARatPMID:12821041|RGD:1300196
Biological ProcessGO:0070309lens fiber cell morphogenesisitga5IMPZFIN:ZDB-GENO-130129-1ZfishPMID:23097490
Biological ProcessGO:0002089lens morphogenesis in camera-type eyeitga5IMPZFIN:ZDB-GENO-130129-1ZfishPMID:23097490
Biological ProcessGO:0007159leukocyte cell-cell adhesionItga5IMPMousePMID:8557754
Biological ProcessGO:0007613memoryItga5IMPMGI:MGI:1857207MousePMID:12904471
Biological ProcessGO:2000811negative regulation of anoikisITGA5IMPHumanPMID:15006356
Biological ProcessGO:0060037pharyngeal system developmentitga5IGIZFIN:ZDB-GENO-221208-14ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IMPZFIN:ZDB-GENO-221208-8ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IGIZFIN:ZDB-GENO-221208-11ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IGIZFIN:ZDB-GENO-221208-10ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IGIZFIN:ZDB-GENO-221208-9ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IMPZFIN:ZDB-GENO-221208-4ZfishPMID:35732225
Biological ProcessGO:0060037pharyngeal system developmentitga5IGIZFIN:ZDB-GENO-221208-5ZfishPMID:35732225
Biological ProcessGO:0030335positive regulation of cell migrationItga5IMPRatPMID:18167060|RGD:2314623
Biological ProcessGO:0010811positive regulation of cell-substrate adhesionItga5IMPRatPMID:18167060|RGD:2314623
Biological ProcessGO:0050731positive regulation of peptidyl-tyrosine phosphorylationITGA5IMPHumanPMID:10022831
Biological ProcessGO:1903672positive regulation of sprouting angiogenesisITGA5IMPHumanPMID:19460962
Biological ProcessGO:0045765regulation of angiogenesisItga5IGIRNAcentral:URS0000329B12_10090MouseMGI:MGI:3849520|PMID:19460962
Biological ProcessGO:0060041retina development in camera-type eyeitga5IMPZFIN:ZDB-CRISPR-191009-71,ZFIN:ZDB-CRISPR-191009-72ZfishPMID:30924555
Biological ProcessGO:0001501skeletal system developmentitga5IMPZFIN:ZDB-GENO-040930-12ZfishPMID:15269787
Biological ProcessGO:0032525somite rostral/caudal axis specificationitga5IGIZFIN:ZDB-GENO-100512-3,ZFIN:ZDB-MRPHLNO-070519-3ZfishPMID:23192979
Biological ProcessGO:0032525somite rostral/caudal axis specificationitga5IGIZFIN:ZDB-GENO-100512-2,ZFIN:ZDB-MRPHLNO-070519-3ZfishPMID:23192979
Biological ProcessGO:0001756somitogenesisitga5IMPZFIN:ZDB-GENO-050621-1ZfishPMID:15809039
Biological ProcessGO:0001756somitogenesisitga5IMPZFIN:ZDB-GENO-050621-2ZfishPMID:15809039
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENE-000426-1ZfishPMID:15809040
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-100512-3,ZFIN:ZDB-MRPHLNO-050712-3ZfishPMID:23192979
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-100512-3,ZFIN:ZDB-MRPHLNO-070519-3ZfishPMID:23192979
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-050209-19,ZFIN:ZDB-GENO-050622-1ZfishPMID:15809039
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-100512-2,ZFIN:ZDB-MRPHLNO-050712-3ZfishPMID:23192979
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-050713-1ZfishPMID:15809040
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-MRPHLNO-050712-3ZfishPMID:15809040
Biological ProcessGO:0001756somitogenesisitga5IMPZFIN:ZDB-MRPHLNO-050712-1,ZFIN:ZDB-MRPHLNO-050713-1ZfishPMID:15809040
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-100512-2,ZFIN:ZDB-MRPHLNO-070519-3ZfishPMID:23192979
Biological ProcessGO:0001756somitogenesisitga5IGIZFIN:ZDB-GENO-050622-1,ZFIN:ZDB-MRPHLNO-050620-2ZfishPMID:15809039
Biological ProcessGO:0001944vasculature developmentitga5IMPZFIN:ZDB-MRPHLNO-150722-1ZfishPMID:23362312
Biological ProcessGO:0001944vasculature developmentitga5IGIZFIN:ZDB-GENE-030616-572ZfishPMID:23362312
Biological ProcessGO:0035313wound healing, spreading of epidermal cellsITGA5IEPHumanPMID:14970227

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory