Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Itgb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ITGB1
- Mouse genes Itgb1
- Rat genes Itgb1
- Zfish genes itgb1a,itgb1b,itgb1b.1,itgb1b.2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itgb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	ITGB1	IDA		Human	PMID:16803572
Molecular Function	GO:0003779	actin binding	Itgb1	IDA		Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0051393	alpha-actinin binding	Itgb1	IDA		Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0019960	C-X3-C chemokine binding	ITGB1	IDA		Human	PMID:23125415
Molecular Function	GO:0045296	cadherin binding	ITGB1	HDA		Human	PMID:25468996
Molecular Function	GO:0050839	cell adhesion molecule binding	ITGB1	IPI	UniProtKB:Q86YT9	Human	PMID:12869515
Molecular Function	GO:0005518	collagen binding	Itgb1	IDA		Rat	PMID:1835909\|RGD:2325829
Molecular Function	GO:0098639	collagen binding involved in cell-matrix adhesion	ITGB1	IMP		Human	PMID:24823363
Molecular Function	GO:0001968	fibronectin binding	ITGB1	IPI	UniProtKB:P02751	Human	PMID:11792823
Molecular Function	GO:0001968	fibronectin binding	ITGB1	IDA		Human	PMID:26763945
Molecular Function	GO:0001968	fibronectin binding	Itgb1	IDA		Rat	PMID:1835909\|RGD:2325829
Molecular Function	GO:0001968	fibronectin binding	itgb1a	IGI	ZFIN:ZDB-GENE-000426-1,ZFIN:ZDB-GENE-031116-52	Zfish	PMID:19641014
Molecular Function	GO:0005178	integrin binding	Itgb1	IPI	PR:Q61739-2	Mouse	PMID:1833411
Molecular Function	GO:0005178	integrin binding	Itgb1	IPI	PR:P11688	Mouse	PMID:8601592
Molecular Function	GO:0005178	integrin binding	Itgb1	IMP		Rat	PMID:17118629\|RGD:1625131
Molecular Function	GO:0005178	integrin binding	Itgb1	IPI	RGD:2925	Rat	PMID:18167060\|RGD:2314623
Molecular Function	GO:0005178	integrin binding	Itgb1	IPI	RGD:1310333	Rat	PMID:2223092\|RGD:2325828
Molecular Function	GO:0019900	kinase binding	Itgb1	IPI	RGD:3443	Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0019900	kinase binding	Itgb1	IPI	RGD:70982	Rat	PMID:18677563\|RGD:2325671
Molecular Function	GO:0043236	laminin binding	Itgb1	IDA		Mouse	PMID:1839357
Molecular Function	GO:0043236	laminin binding	Itgb1	IDA		Rat	PMID:1835909\|RGD:2325829
Molecular Function	GO:0043236	laminin binding	Itgb1	IMP		Rat	PMID:18635166\|RGD:2325290
Molecular Function	GO:0002020	protease binding	ITGB1	IPI	UniProtKB:Q12884	Human	PMID:10455171
Molecular Function	GO:0002020	protease binding	Itgb1	IPI	RGD:620198	Rat	PMID:19027888\|RGD:2307395
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P17301	Human	PMID:10397731
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O75369	Human	PMID:10676904
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q9Y490	Human	PMID:11279249
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O14713	Human	PMID:11807099
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O14713	Human	PMID:12473654
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q9Y490	Human	PMID:12473654
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P05556	Human	PMID:12500944
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P03192	Human	PMID:12592401
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P48745	Human	PMID:12695522
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:12724312
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21926	Human	PMID:12796480
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P35555	Human	PMID:12807887
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13612	Human	PMID:14681217
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P17301	Human	PMID:14681217
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P78536	Human	PMID:14970227
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08069	Human	PMID:15289498
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13612	Human	PMID:1542691
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O88572	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13612,UniProtKB:P21741	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13612\|UniProtKB:P23229	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21741	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21741,UniProtKB:P23229	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q62656	Human	PMID:15466886
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O14713	Human	PMID:15703214
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q14315	Human	PMID:16076904
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:16099422
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q07092	Human	PMID:16754661
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P35282	Human	PMID:16754960
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P46939	Human	PMID:16803572
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P35555	Human	PMID:17158881
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21333	Human	PMID:17690686
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q13443	Human	PMID:17704059
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P57735	Human	PMID:17925226
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21333	Human	PMID:18177638
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P46109	Human	PMID:19168626
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O00214	Human	PMID:19268462
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P07948	Human	PMID:20159608
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13612	Human	PMID:20159608
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P13796	Human	PMID:20183869
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P32927	Human	PMID:20802515
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P26039	Human	PMID:21134644
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q9BY76	Human	PMID:21397862
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P18031	Human	PMID:21806020
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:21947080
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P17301	Human	PMID:21947080
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P26039	Human	PMID:21947080
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:22178926
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P78536	Human	PMID:22413019
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:22451694
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P12821-3	Human	PMID:22523556
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q9BYF1	Human	PMID:22523556
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P17813	Human	PMID:22940691
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P78423	Human	PMID:24789099
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P23142	Human	PMID:25661773
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q8NBH6	Human	PMID:25661773
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P42684	Human	PMID:25694433
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P78536	Human	PMID:30455686
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648,UniProtKB:P29965	Human	PMID:31331973
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O60784-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:Q13387-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08648,UniProtKB:P0DTC2,UniProtKB:Q9BYF1	Human	PMID:33102950
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P08069	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O14713	Human	PMID:9281591
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:O14817	Human	PMID:9360996
Molecular Function	GO:0005515	protein binding	ITGB1	IPI	UniProtKB:P21333	Human	PMID:9722563
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P26955	Mouse	MGI:MGI:5050060\|PMID:20802515
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:Q91YD9	Mouse	MGI:MGI:5002755\|PMID:21427700
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:Q9QUR8	Mouse	MGI:MGI:3710037\|PMID:17377534
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P40240	Mouse	MGI:MGI:1351541\|PMID:10634791
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P21741\|UniProtKB:Q61739	Mouse	MGI:MGI:6294160\|PMID:15466886
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:Q8K1B8	Mouse	MGI:MGI:3783912\|PMID:18278053
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:O88662	Mouse	MGI:MGI:5605959\|PMID:12189152
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:Q01768\|UniProtKB:Q6F5E0	Mouse	MGI:MGI:3688344\|PMID:15102471
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P02469	Mouse	MGI:MGI:6810807\|PMID:34427057
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P12814\|UniProtKB:Q7TPR4	Mouse	MGI:MGI:5640954\|PMID:11223950
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	UniProtKB:P11835,UniProtKB:P20491,UniProtKB:P35762,UniProtKB:Q08857\|UniProtKB:P11835,UniProtKB:P20491,UniProtKB:P40240,UniProtKB:Q08857	Mouse	MGI:MGI:5700288\|PMID:23395392
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:Q4JIM5	Mouse	PMID:22357865
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:Q62470	Mouse	PMID:12904471
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:Q9D7C9	Mouse	PMID:10613898
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:Q80UW2	Mouse	PMID:15723043
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:Q8BGS1	Mouse	PMID:18794329
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	PR:P11688	Mouse	PMID:12904471
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:1305759	Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:1306247	Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:3886	Rat	PMID:18658130\|RGD:2325684
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:2507	Rat	PMID:18677563\|RGD:2325671
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:1311191	Rat	PMID:8020590\|RGD:2317878
Molecular Function	GO:0005515	protein binding	Itgb1	IPI	RGD:3169	Rat	PMID:9858254\|RGD:1599274
Molecular Function	GO:0019904	protein domain specific binding	Itgb1	IDA		Rat	PMID:18658130\|RGD:2325684
Molecular Function	GO:0046982	protein heterodimerization activity	ITGB1	IDA		Human	PMID:10455171
Molecular Function	GO:0046982	protein heterodimerization activity	itgb1b	IPI	UniProtKB:B3DJJ0	Zfish	PMID:19747169
Molecular Function	GO:0046982	protein heterodimerization activity	itgb1a	IPI	UniProtKB:B3DJJ0	Zfish	PMID:19641014
Molecular Function	GO:0046982	protein heterodimerization activity	itgb1a	IPI	UniProtKB:B3DJJ0	Zfish	PMID:19747169
Molecular Function	GO:0019901	protein kinase binding	Itgb1	IPI	RGD:620063	Rat	PMID:11133699\|RGD:2302097
Molecular Function	GO:0019901	protein kinase binding	Itgb1	IPI	RGD:3443	Rat	PMID:18465789\|RGD:2325691
Molecular Function	GO:1990782	protein tyrosine kinase binding	ITGB1	IPI	UniProtKB:Q05397	Human	PMID:26763945
Molecular Function	GO:0044877	protein-containing complex binding	ITGB1	IPI	UniProtKB:P17301,UniProtKB:Q12864	Human	PMID:25336636
Molecular Function	GO:0044877	protein-containing complex binding	Itgb1	IPI	RGD:1306247\|RGD:3443\|RGD:1305759	Rat	PMID:16935300\|RGD:2325674
Molecular Function	GO:0044877	protein-containing complex binding	Itgb1	IMP		Rat	PMID:17118629\|RGD:1625131
Molecular Function	GO:0044877	protein-containing complex binding	Itgb1	IPI	RGD:1321178	Rat	PMID:2223092\|RGD:2325828
Molecular Function	GO:0005102	signaling receptor binding	Itgb1	IPI	RGD:2681	Rat	PMID:18465789\|RGD:2325691
Molecular Function	GO:0005102	signaling receptor binding	Itgb1	IPI	RGD:2277	Rat	PMID:21969374\|RGD:7205691
Cellular Component	GO:0001669	acrosomal vesicle	Itgb1	IDA		Rat	PMID:9202984\|RGD:1581320
Cellular Component	GO:0005912	adherens junction	Itgb1	IDA		Rat	PMID:18579774\|RGD:2325293
Cellular Component	GO:0005604	basement membrane	Itgb1	IDA		Rat	PMID:18596883\|RGD:2325689
Cellular Component	GO:0005604	basement membrane	Itgb1	IDA		Rat	PMID:9202984\|RGD:1581320
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:17158881
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:1715889
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:19234460
Cellular Component	GO:0009986	cell surface	ITGB1	HDA		Human	PMID:19581412
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:19933311
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:20563599
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:21310825
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:23023225
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:23154389
Cellular Component	GO:0009986	cell surface	ITGB1	HDA		Human	PMID:23382103
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:23620790
Cellular Component	GO:0009986	cell surface	ITGB1	HDA		Human	PMID:23658023
Cellular Component	GO:0009986	cell surface	ITGB1	HDA		Human	PMID:23981064
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:24036928
Cellular Component	GO:0009986	cell surface	ITGB1	IDA		Human	PMID:25063885
Cellular Component	GO:0009986	cell surface	Itgb1	IDA		Mouse	MGI:MGI:5469937\|PMID:23023225
Cellular Component	GO:0009986	cell surface	Itgb1	IDA		Mouse	PMID:8306881
Cellular Component	GO:0009986	cell surface	Itgb1	IDA		Rat	PMID:19705458\|RGD:2325329
Cellular Component	GO:0005911	cell-cell junction	Itgb1	IDA		Rat	PMID:11133699\|RGD:2302097
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	Itgb1	IDA		Mouse	PMID:24831527
Cellular Component	GO:0150053	cerebellar climbing fiber to Purkinje cell synapse	Itgb1	IMP		Mouse	PMID:24831527
Cellular Component	GO:0005737	cytoplasm	ITGB1	IDA		Human	PMID:16803572
Cellular Component	GO:0031410	cytoplasmic vesicle	Itgb1	IDA		Mouse	MGI:MGI:5605959\|PMID:12189152
Cellular Component	GO:0043197	dendritic spine	Itgb1	IDA		Mouse	PMID:22357865
Cellular Component	GO:0043197	dendritic spine	Itgb1	IDA		Rat	PMID:22973009\|RGD:12050116
Cellular Component	GO:0009897	external side of plasma membrane	Itgb1	IDA		Mouse	PMID:9553049
Cellular Component	GO:0009897	external side of plasma membrane	Itgb1	IDA		Mouse	PMID:20103531
Cellular Component	GO:0009897	external side of plasma membrane	Itgb1	IDA		Mouse	PMID:19487454
Cellular Component	GO:0070062	extracellular exosome	ITGB1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ITGB1	HDA		Human	PMID:23533145
Cellular Component	GO:0030175	filopodium	ITGB1	IDA		Human	PMID:16803572
Cellular Component	GO:0005925	focal adhesion	ITGB1	IDA		Human	PMID:14970227
Cellular Component	GO:0005925	focal adhesion	ITGB1	IDA		Human	PMID:12417594
Cellular Component	GO:0005925	focal adhesion	ITGB1	IDA		Human	PMID:17158881
Cellular Component	GO:0005925	focal adhesion	ITGB1	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	ITGB1	IDA		Human	PMID:23023225
Cellular Component	GO:0005925	focal adhesion	ITGB1	IDA		Human	PMID:29162887
Cellular Component	GO:0005925	focal adhesion	Itgb1	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0005925	focal adhesion	Itgb1	IDA		Rat	PMID:19027888\|RGD:2307395
Cellular Component	GO:0097386	glial cell projection	Itgb1	IDA		Rat	PMID:20091784\|RGD:6480646
Cellular Component	GO:0098978	glutamatergic synapse	Itgb1	IDA		Mouse	PMID:16467530
Cellular Component	GO:0098978	glutamatergic synapse	Itgb1	IDA		Rat	PMID:22973009\|RGD:12050116
Cellular Component	GO:0098690	glycinergic synapse	Itgb1	EXP		Rat	PMID:20935643\|RGD:155230798
Cellular Component	GO:0098690	glycinergic synapse	Itgb1	IDA		Rat	PMID:20935643\|RGD:155230798
Cellular Component	GO:0030056	hemidesmosome	Itgb1	IDA		Rat	PMID:18579774\|RGD:2325293
Cellular Component	GO:0034665	integrin alpha1-beta1 complex	ITGB1	IDA		Human	PMID:24823363
Cellular Component	GO:0034680	integrin alpha10-beta1 complex	ITGB1	IDA		Human	PMID:24823363
Cellular Component	GO:0034681	integrin alpha11-beta1 complex	ITGB1	IDA		Human	PMID:24823363
Cellular Component	GO:0034666	integrin alpha2-beta1 complex	ITGB1	IDA		Human	PMID:24823363
Cellular Component	GO:0034667	integrin alpha3-beta1 complex	ITGB1	IDA		Human	PMID:24220332
Cellular Component	GO:0034667	integrin alpha3-beta1 complex	ITGB1	IDA		Human	PMID:25063885
Cellular Component	GO:0034667	integrin alpha3-beta1 complex	Itgb1	IDA		Rat	PMID:1835909\|RGD:2325829
Cellular Component	GO:0034674	integrin alpha5-beta1 complex	ITGB1	IPI		Human	PMID:22451694
Cellular Component	GO:0034674	integrin alpha5-beta1 complex	ITGB1	IDA		Human	PMID:31331973
Cellular Component	GO:0034674	integrin alpha5-beta1 complex	ITGB1	IDA		Human	PMID:33102950
Cellular Component	GO:0034677	integrin alpha7-beta1 complex	Itgb1	IDA		Mouse	PMID:18611855
Cellular Component	GO:0034677	integrin alpha7-beta1 complex	Itgb1	IPI	PR:Q61738	Mouse	PMID:1839357
Cellular Component	GO:0034679	integrin alpha9-beta1 complex	Itgb1	IDA		Rat	PMID:8020590\|RGD:2317878
Cellular Component	GO:0008305	integrin complex	Itgb1	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0014704	intercalated disc	Itgb1	IDA		Mouse	PMID:11732910
Cellular Component	GO:0016020	membrane	ITGB1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Itgb1	IDA		Mouse	MGI:MGI:5700288\|PMID:23395392
Cellular Component	GO:0016020	membrane	Itgb1	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0016020	membrane	Itgb1	IDA		Rat	PMID:9202984\|RGD:1581320
Cellular Component	GO:0045121	membrane raft	ITGB1	IDA		Human	PMID:14559243
Cellular Component	GO:0045121	membrane raft	Itgb1	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0045121	membrane raft	Itgb1	IDA		Rat	PMID:19118221\|RGD:2325333
Cellular Component	GO:0035748	myelin sheath abaxonal region	Itgb1	IDA		Mouse	MGI:MGI:4441217\|PMID:20237282
Cellular Component	GO:0031594	neuromuscular junction	ITGB1	IDA		Human	PMID:9415431
Cellular Component	GO:0031594	neuromuscular junction	Itgb1	IDA		Mouse	PMID:9415431
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ITGB1	IDA		Human	PMID:20183869
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Itgb1	IDA		Mouse	MGI:MGI:5605959\|PMID:12189152
Cellular Component	GO:0005886	plasma membrane	ITGB1	IDA		Human	PMID:12869515
Cellular Component	GO:0005886	plasma membrane	ITGB1	IDA		Human	PMID:16803572
Cellular Component	GO:0005886	plasma membrane	ITGB1	IDA		Human	PMID:21310825
Cellular Component	GO:0005886	plasma membrane	Itgb1	IDA		Mouse	MGI:MGI:5605959\|PMID:12189152
Cellular Component	GO:0005886	plasma membrane	Itgb1	IDA		Mouse	PMID:14522949
Cellular Component	GO:0005886	plasma membrane	Itgb1	IDA		Mouse	PMID:12591243
Cellular Component	GO:0005886	plasma membrane	Itgb1	IDA		Mouse	PMID:12670870
Cellular Component	GO:0045211	postsynaptic membrane	Itgb1	IDA		Rat	PMID:22973009\|RGD:12050116
Cellular Component	GO:0043235	receptor complex	ITGB1	IDA		Human	PMID:23382219
Cellular Component	GO:0032587	ruffle membrane	ITGB1	IDA		Human	PMID:14970227
Cellular Component	GO:0042383	sarcolemma	ITGB1	IDA		Human	PMID:9415431
Cellular Component	GO:0042383	sarcolemma	Itgb1	IDA		Mouse	PMID:9415431
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Itgb1	IMP		Mouse	PMID:17065460
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Itgb1	IDA		Mouse	PMID:17065460
Cellular Component	GO:0045202	synapse	Itgb1	IDA		Mouse	PMID:12904471
Cellular Component	GO:0097060	synaptic membrane	Itgb1	IDA		Mouse	PMID:22357865
Cellular Component	GO:0097060	synaptic membrane	Itgb1	IDA		Mouse	PMID:16467530
Biological Process	GO:0003181	atrioventricular valve morphogenesis	itgb1a	IMP	ZFIN:ZDB-GENO-200113-10	Zfish	PMID:30635353
Biological Process	GO:0048675	axon extension	Itgb1	IMP		Mouse	PMID:12879062
Biological Process	GO:0048675	axon extension	Itgb1	IGI	MGI:MGI:1306826	Mouse	PMID:12879062
Biological Process	GO:0071711	basement membrane organization	Itgb1	IMP		Mouse	MGI:MGI:5571208\|PMID:24681597
Biological Process	GO:0070830	bicellular tight junction assembly	Itgb1	IMP		Rat	PMID:18579774\|RGD:2325293
Biological Process	GO:0001568	blood vessel development	itgb1b	IMP	ZFIN:ZDB-GENO-200408-1	Zfish	PMID:30151851
Biological Process	GO:0007161	calcium-independent cell-matrix adhesion	ITGB1	IGI	UniProtKB:Q70UZ7	Human	PMID:19651211
Biological Process	GO:0060912	cardiac cell fate specification	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:9004034
Biological Process	GO:0055013	cardiac muscle cell development	itgb1b	IMP	ZFIN:ZDB-MRPHLNO-080319-2	Zfish	PMID:26310270
Biological Process	GO:0055013	cardiac muscle cell development	itgb1b	IGI	ZFIN:ZDB-MRPHLNO-080319-2,ZFIN:ZDB-MRPHLNO-160217-1	Zfish	PMID:26310270
Biological Process	GO:0055007	cardiac muscle cell differentiation	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:9004034
Biological Process	GO:0060379	cardiac muscle cell myoblast differentiation	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:9004034
Biological Process	GO:0023035	CD40 signaling pathway	ITGB1	IDA		Human	PMID:31331973
Biological Process	GO:0007155	cell adhesion	ITGB1	IDA		Human	PMID:19703720
Biological Process	GO:0007155	cell adhesion	itgb1b	IMP	ZFIN:ZDB-GENO-200305-7	Zfish	PMID:30566586
Biological Process	GO:0033627	cell adhesion mediated by integrin	ITGB1	IDA		Human	PMID:12807887
Biological Process	GO:0033627	cell adhesion mediated by integrin	ITGB1	IDA		Human	PMID:17158881
Biological Process	GO:0033627	cell adhesion mediated by integrin	Itgb1	IGI	UniProtKB:Q9EPX4	Rat	PMID:20091784\|RGD:6480646
Biological Process	GO:0033627	cell adhesion mediated by integrin	itgb1b	IMP	ZFIN:ZDB-MRPHLNO-080319-2	Zfish	PMID:31006651
Biological Process	GO:0033627	cell adhesion mediated by integrin	itgb1b	IMP	ZFIN:ZDB-GENO-200409-23	Zfish	PMID:31006651
Biological Process	GO:0016477	cell migration	itgb1b	IMP		Zfish	PMID:24599960
Biological Process	GO:0042074	cell migration involved in gastrulation	itgb1b	IMP	ZFIN:ZDB-MRPHLNO-101103-2	Zfish	PMID:20843856
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	Itgb1	IMP		Mouse	PMID:16424942
Biological Process	GO:0008283	cell population proliferation	Itgb1	IMP	MGI:MGI:2156945	Mouse	PMID:15056720
Biological Process	GO:0030030	cell projection organization	Itgb1	IMP		Rat	PMID:20091784\|RGD:6480646
Biological Process	GO:0033631	cell-cell adhesion mediated by integrin	ITGB1	IEP		Human	PMID:17704059
Biological Process	GO:0007160	cell-matrix adhesion	ITGB1	IMP		Human	PMID:18156211
Biological Process	GO:0007160	cell-matrix adhesion	ITGB1	IMP		Human	PMID:18308860
Biological Process	GO:0007160	cell-matrix adhesion	ITGB1	IMP		Human	PMID:24823363
Biological Process	GO:0007160	cell-matrix adhesion	Itgb1	IMP	MGI:MGI:2156945,MGI:MGI:2684610	Mouse	PMID:21185282
Biological Process	GO:0007160	cell-matrix adhesion	Itgb1	IGI	MGI:MGI:1933825	Mouse	PMID:17099249
Biological Process	GO:0031589	cell-substrate adhesion	ITGB1	IMP		Human	PMID:19933311
Biological Process	GO:0031589	cell-substrate adhesion	ITGB1	IMP		Human	PMID:19940135
Biological Process	GO:0071479	cellular response to ionizing radiation	Itgb1	IEP		Rat	PMID:19714308\|RGD:2312872
Biological Process	GO:0071404	cellular response to low-density lipoprotein particle stimulus	Itgb1	IDA		Mouse	MGI:MGI:5700288\|PMID:23395392
Biological Process	GO:0071260	cellular response to mechanical stimulus	Itgb1	IEP		Rat	PMID:19720043\|RGD:2325327
Biological Process	GO:0071305	cellular response to vitamin D	Itgb1	IEP		Rat	PMID:20304064\|RGD:2325261
Biological Process	GO:0048813	dendrite morphogenesis	Itgb1	IMP	MGI:MGI:2156945,MGI:MGI:2668659	Mouse	PMID:22357865
Biological Process	GO:0048813	dendrite morphogenesis	Itgb1	IGI	MGI:MGI:87860	Mouse	PMID:22357865
Biological Process	GO:0007368	determination of left/right symmetry	itgb1b	IGI	ZFIN:ZDB-MRPHLNO-101103-2,ZFIN:ZDB-MRPHLNO-110921-1	Zfish	PMID:21876750
Biological Process	GO:0090674	endothelial cell-matrix adhesion via fibronectin	itgb1b	IMP	ZFIN:ZDB-GENO-200409-23	Zfish	PMID:31006651
Biological Process	GO:0070371	ERK1 and ERK2 cascade	itgb1a	IMP	ZFIN:ZDB-GENO-180523-5	Zfish	PMID:27780917
Biological Process	GO:0000132	establishment of mitotic spindle orientation	ITGB1	IMP		Human	PMID:30992345
Biological Process	GO:0097368	establishment of Sertoli cell barrier	Itgb1	IEP		Rat	PMID:22872576\|RGD:7207404
Biological Process	GO:0021943	formation of radial glial scaffolds	Itgb1	IMP	MGI:MGI:2156945,MGI:MGI:2684610	Mouse	PMID:21185282
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	Itgb1	IMP	MGI:MGI:1926498	Mouse	PMID:12957148
Biological Process	GO:0008354	germ cell migration	Itgb1	IMP	MGI:MGI:2154538	Mouse	PMID:10079228
Biological Process	GO:0021782	glial cell development	itgb1a	IMP	ZFIN:ZDB-CRISPR-191009-74,ZFIN:ZDB-CRISPR-191009-75	Zfish	PMID:30924555
Biological Process	GO:0034113	heterotypic cell-cell adhesion	ITGB1	IMP		Human	PMID:20563599
Biological Process	GO:0001701	in utero embryonic development	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:7544313
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB1	IMP		Human	PMID:24823363
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB1	IDA		Human	PMID:31331973
Biological Process	GO:0007229	integrin-mediated signaling pathway	Itgb1	IMP		Rat	PMID:22973009\|RGD:12050116
Biological Process	GO:0070121	Kupffer's vesicle development	itgb1b	IMP	ZFIN:ZDB-MRPHLNO-101103-2	Zfish	PMID:20843856
Biological Process	GO:0030032	lamellipodium assembly	Itgb1	IMP		Rat	PMID:20091784\|RGD:6480646
Biological Process	GO:0007159	leukocyte cell-cell adhesion	ITGB1	IDA		Human	PMID:1715889
Biological Process	GO:0050901	leukocyte tethering or rolling	ITGB1	IMP		Human	PMID:18308860
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Itgb1	EXP		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Itgb1	IDA		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0060135	maternal process involved in female pregnancy	Itgb1	IEP		Rat	PMID:20353731\|RGD:2325260
Biological Process	GO:0048333	mesodermal cell differentiation	ITGB1	IEP		Human	PMID:23154389
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Itgb1	IMP		Mouse	PMID:17065460
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Itgb1	IDA		Mouse	PMID:17065460
Biological Process	GO:0048626	myoblast fate specification	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:9004034
Biological Process	GO:2000811	negative regulation of anoikis	ITGB1	IMP		Human	PMID:15006356
Biological Process	GO:0043066	negative regulation of apoptotic process	Itgb1	IDA		Rat	PMID:28367125\|RGD:13602094
Biological Process	GO:0008285	negative regulation of cell population proliferation	Itgb1	IMP		Rat	PMID:18658130\|RGD:2325684
Biological Process	GO:0031345	negative regulation of cell projection organization	Itgb1	IMP		Rat	PMID:20039268\|RGD:2325266
Biological Process	GO:0045665	negative regulation of neuron differentiation	Itgb1	IMP	MGI:MGI:2156945	Mouse	PMID:15056720
Biological Process	GO:0045665	negative regulation of neuron differentiation	Itgb1	IMP		Rat	PMID:18658130\|RGD:2325684
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Itgb1	IGI	MGI:MGI:1929494	Mouse	PMID:22357865
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Itgb1	IGI	MGI:MGI:87860	Mouse	PMID:22357865
Biological Process	GO:0007405	neuroblast proliferation	Itgb1	IMP	MGI:MGI:2156945	Mouse	PMID:15056720
Biological Process	GO:0030182	neuron differentiation	Itgb1	IMP	MGI:MGI:2156945	Mouse	PMID:15056720
Biological Process	GO:0031175	neuron projection development	Itgb1	IMP		Mouse	PMID:19118221
Biological Process	GO:0007219	Notch signaling pathway	itgb1b	IMP	ZFIN:ZDB-GENO-200409-12	Zfish	PMID:31006651
Biological Process	GO:0007219	Notch signaling pathway	itgb1b	IMP	ZFIN:ZDB-GENO-200409-23	Zfish	PMID:31006651
Biological Process	GO:0006909	phagocytosis	Itgb1	IMP		Rat	PMID:17410128\|RGD:13673830
Biological Process	GO:0014065	phosphatidylinositol 3-kinase signaling	itgb1a	IMP	ZFIN:ZDB-GENO-180523-5	Zfish	PMID:27780917
Biological Process	GO:0045766	positive regulation of angiogenesis	ITGB1	IMP		Human	PMID:24044949
Biological Process	GO:0043065	positive regulation of apoptotic process	ITGB1	IGI	UniProtKB:P18406	Human	PMID:19364818
Biological Process	GO:0043065	positive regulation of apoptotic process	ITGB1	IGI	UniProtKB:P23229	Human	PMID:19364818
Biological Process	GO:0043065	positive regulation of apoptotic process	ITGB1	IGI	UniProtKB:P48023	Human	PMID:19364818
Biological Process	GO:0030335	positive regulation of cell migration	Itgb1	IMP		Rat	PMID:15466886\|RGD:14397578
Biological Process	GO:0030335	positive regulation of cell migration	Itgb1	IMP		Rat	PMID:18167060\|RGD:2314623
Biological Process	GO:0030335	positive regulation of cell migration	Itgb1	IMP		Rat	PMID:19686792\|RGD:2325662
Biological Process	GO:0030335	positive regulation of cell migration	Itgb1	IMP		Rat	PMID:19705458\|RGD:2325329
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Itgb1	IMP		Rat	PMID:18167060\|RGD:2314623
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Itgb1	IMP		Rat	PMID:19705458\|RGD:2325329
Biological Process	GO:0045807	positive regulation of endocytosis	Itgb1	IMP		Rat	PMID:18577581\|RGD:2325690
Biological Process	GO:0010763	positive regulation of fibroblast migration	ITGB1	IDA		Human	PMID:26763945
Biological Process	GO:0051951	positive regulation of glutamate uptake involved in transmission of nerve impulse	Itgb1	IMP		Mouse	MGI:MGI:5629870\|PMID:25716834
Biological Process	GO:0043547	positive regulation of GTPase activity	ITGB1	IMP		Human	PMID:25911094
Biological Process	GO:0002052	positive regulation of neuroblast proliferation	Itgb1	IMP	MGI:MGI:2156945	Mouse	PMID:15056720
Biological Process	GO:0045666	positive regulation of neuron differentiation	Itgb1	IMP		Rat	PMID:18658130\|RGD:2325684
Biological Process	GO:0010976	positive regulation of neuron projection development	Itgb1	IMP		Rat	PMID:14564503\|RGD:1579850
Biological Process	GO:0010976	positive regulation of neuron projection development	Itgb1	IMP		Rat	PMID:19118221\|RGD:2325333
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Itgb1	IMP		Rat	PMID:18465789\|RGD:2325691
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ITGB1	IDA		Human	PMID:24044949
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	ITGB1	IDA		Human	PMID:10455171
Biological Process	GO:2000273	positive regulation of signaling receptor activity	ITGB1	IDA		Human	PMID:24044949
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	itgb1a	IGI	ZFIN:ZDB-GENE-040718-157	Zfish	PMID:27780917
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	itgb1a	IMP	ZFIN:ZDB-MRPHLNO-080319-1	Zfish	PMID:27780917
Biological Process	GO:0090303	positive regulation of wound healing	ITGB1	IDA		Human	PMID:26763945
Biological Process	GO:0032594	protein transport within lipid bilayer	Itgb1	IMP		Rat	PMID:19420267\|RGD:2325331
Biological Process	GO:0150103	reactive gliosis	Itgb1	IMP		Mouse	MGI:MGI:5629870\|PMID:25716834
Biological Process	GO:0031623	receptor internalization	Itgb1	IDA		Mouse	MGI:MGI:5700288\|PMID:23395392
Biological Process	GO:0051726	regulation of cell cycle	Itgb1	IMP	MGI:MGI:1926498	Mouse	PMID:14522949
Biological Process	GO:0010710	regulation of collagen catabolic process	ITGB1	IDA		Human	PMID:10455171
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Itgb1	IMP		Rat	PMID:17157995\|RGD:1625132
Biological Process	GO:1901979	regulation of inward rectifier potassium channel activity	Itgb1	IMP		Mouse	MGI:MGI:5629870\|PMID:25716834
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Itgb1	EXP		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Itgb1	IDA		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0150003	regulation of spontaneous synaptic transmission	Itgb1	IMP		Mouse	MGI:MGI:5629870\|PMID:25716834
Biological Process	GO:1905806	regulation of synapse pruning	Itgb1	IDA		Mouse	PMID:24831527
Biological Process	GO:1905806	regulation of synapse pruning	Itgb1	IMP		Mouse	PMID:24831527
Biological Process	GO:0043114	regulation of vascular permeability	itgb1b	IMP	ZFIN:ZDB-GENO-200408-1	Zfish	PMID:30151851
Biological Process	GO:0014823	response to activity	Itgb1	IEP		Rat	PMID:18378961\|RGD:2325302
Biological Process	GO:0034698	response to gonadotropin	Itgb1	IEP		Rat	PMID:20189708\|RGD:2325263
Biological Process	GO:0031667	response to nutrient levels	Itgb1	IEP		Rat	PMID:20200130\|RGD:2325321
Biological Process	GO:0071559	response to transforming growth factor beta	Itgb1	IEP		Rat	PMID:18378961\|RGD:2325302
Biological Process	GO:0009410	response to xenobiotic stimulus	Itgb1	IEP		Rat	PMID:20368265\|RGD:2324624
Biological Process	GO:0060041	retina development in camera-type eye	itgb1a	IMP	ZFIN:ZDB-CRISPR-191009-74,ZFIN:ZDB-CRISPR-191009-75	Zfish	PMID:30924555
Biological Process	GO:0045214	sarcomere organization	Itgb1	IMP	MGI:MGI:2154539	Mouse	PMID:9004034
Biological Process	GO:0045214	sarcomere organization	itgb1b	IMP	ZFIN:ZDB-MRPHLNO-080319-2	Zfish	PMID:26310270
Biological Process	GO:0001894	tissue homeostasis	Itgb1	IMP		Rat	PMID:17118629\|RGD:1625131
Biological Process	GO:0008542	visual learning	Itgb1	IGI	MGI:MGI:87860	Mouse	PMID:22357865
Biological Process	GO:0008542	visual learning	Itgb1	IMP	MGI:MGI:2156945,MGI:MGI:2668659	Mouse	PMID:22357865

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/21/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.