Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITGB1BP1
  • Mouse genes Itgb1bp1
  • Rat genes Itgb1bp1
  • Zfish genes itgb1bp1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itgb1bp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005092	GDP-dissociation inhibitor activity	ITGB1BP1	IDA		Human	PMID:11807099
Molecular Function	GO:0005178	integrin binding	ITGB1BP1	IPI	UniProtKB:P05556	Human	PMID:12473654
Molecular Function	GO:0005178	integrin binding	ITGB1BP1	IDA		Human	PMID:15703214
Molecular Function	GO:0019900	kinase binding	Itgb1bp1	IPI	UniProtKB:P70335	Mouse	MGI:MGI:5486551|PMID:17654484
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P05556	Human	PMID:11807099
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P60953	Human	PMID:11807099
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P63000	Human	PMID:11807099
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P22392	Human	PMID:11919189
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P05556	Human	PMID:15703214
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:O00522	Human	PMID:17916086
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:Q6PIW4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:O00522	Human	PMID:25814554
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:O00522	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P09622	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:Q15669	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P00441	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P54253	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ITGB1BP1	IPI	UniProtKB:P05556	Human	PMID:9281591
Molecular Function	GO:0005515	protein binding	Itgb1bp1	IPI	UniProtKB:P70335	Mouse	MGI:MGI:5486556|PMID:16741948
Molecular Function	GO:0019901	protein kinase binding	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Cellular Component	GO:0071944	cell periphery	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0034451	centriolar satellite	ITGB1BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0005737	cytoplasm	ITGB1BP1	IDA		Human	PMID:12473654
Cellular Component	GO:0005737	cytoplasm	ITGB1BP1	IDA		Human	PMID:15703214
Cellular Component	GO:0005856	cytoskeleton	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Cellular Component	GO:0005829	cytosol	ITGB1BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0030027	lamellipodium	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0030027	lamellipodium	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Cellular Component	GO:0016604	nuclear body	ITGB1BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ITGB1BP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ITGB1BP1	IDA		Human	PMID:12473654
Cellular Component	GO:0005634	nucleus	ITGB1BP1	IDA		Human	PMID:15703214
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0005886	plasma membrane	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Cellular Component	GO:0001726	ruffle	ITGB1BP1	IDA		Human	PMID:11919189
Cellular Component	GO:0001726	ruffle	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Biological Process	GO:0032148	activation of protein kinase B activity	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0097746	blood vessel diameter maintenance	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0007160	cell-matrix adhesion	ITGB1BP1	IDA		Human	PMID:9281591
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0033622	integrin activation	ITGB1BP1	IDA		Human	PMID:23317506
Biological Process	GO:0033622	integrin activation	Itgb1bp1	IDA		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB1BP1	IDA		Human	PMID:11919189
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB1BP1	IDA		Human	PMID:15703214
Biological Process	GO:0051451	myoblast migration	Itgb1bp1	IMP		Mouse	MGI:MGI:5486551|PMID:17654484
Biological Process	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration	Itgb1bp1	IDA		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0008285	negative regulation of cell population proliferation	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0070373	negative regulation of ERK1 and ERK2 cascade	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0010764	negative regulation of fibroblast migration	Itgb1bp1	IDA		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	ITGB1BP1	IDA		Human	PMID:12473654
Biological Process	GO:0051895	negative regulation of focal adhesion assembly	Itgb1bp1	IMP		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0032091	negative regulation of protein binding	ITGB1BP1	IDA		Human	PMID:12473654
Biological Process	GO:0006469	negative regulation of protein kinase activity	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	ITGB1BP1	IDA		Human	PMID:11807099
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	ITGB1BP1	IDA		Human	PMID:11807099
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	Itgb1bp1	IDA		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0008284	positive regulation of cell population proliferation	ITGB1BP1	IDA		Human	PMID:15703214
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0051894	positive regulation of focal adhesion assembly	Itgb1bp1	IDA		Mouse	MGI:MGI:5486551|PMID:17654484
Biological Process	GO:0045747	positive regulation of Notch signaling pathway	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Itgb1bp1	IDA		Mouse	MGI:MGI:5486556|PMID:16741948
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Itgb1bp1	IDA		Mouse	MGI:MGI:5486551|PMID:17654484
Biological Process	GO:0051496	positive regulation of stress fiber assembly	Itgb1bp1	IDA		Mouse	MGI:MGI:5486551|PMID:17654484
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ITGB1BP1	IDA		Human	PMID:15703214
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ITGB1BP1	IDA		Human	PMID:20616313
Biological Process	GO:0072659	protein localization to plasma membrane	ITGB1BP1	IDA		Human	PMID:17916086
Biological Process	GO:0043113	receptor clustering	Itgb1bp1	IDA		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0033628	regulation of cell adhesion mediated by integrin	Itgb1bp1	IMP		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0043087	regulation of GTPase activity	ITGB1BP1	IDA		Human	PMID:11807099
Biological Process	GO:2001044	regulation of integrin-mediated signaling pathway	Itgb1bp1	IDA		Mouse	MGI:MGI:5486551|PMID:17654484
Biological Process	GO:2001044	regulation of integrin-mediated signaling pathway	Itgb1bp1	IMP		Mouse	MGI:MGI:5486544|PMID:18227284
Biological Process	GO:0035148	tube formation	ITGB1BP1	IDA		Human	PMID:20616313

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern