Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Itgb3

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ITGB3
- Mouse genes Itgb3
- Rat genes Itgb3
- Zfish genes itgb3a,itgb3b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itgb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019960	C-X3-C chemokine binding	ITGB3	IDA		Human	PMID:23125415
Molecular Function	GO:0050839	cell adhesion molecule binding	ITGB3	IPI	UniProtKB:P04004	Human	PMID:8837777
Molecular Function	GO:0019899	enzyme binding	ITGB3	IPI	UniProtKB:P07237	Human	PMID:21670307
Molecular Function	GO:0019899	enzyme binding	Itgb3	IPI	UniProtKB:P09103	Mouse	MGI:MGI:5014432\|PMID:21670307
Molecular Function	GO:0050840	extracellular matrix binding	ITGB3	IDA		Human	PMID:22505472
Molecular Function	GO:0070051	fibrinogen binding	Itgb3	IDA		Rat	PMID:11278919\|RGD:2316363
Molecular Function	GO:0017134	fibroblast growth factor binding	ITGB3	IDA		Human	PMID:18441324
Molecular Function	GO:0001968	fibronectin binding	ITGB3	IMP		Human	PMID:24658351
Molecular Function	GO:0042802	identical protein binding	ITGB3	IPI	UniProtKB:P05106	Human	PMID:11606749
Molecular Function	GO:0042802	identical protein binding	ITGB3	IPI	UniProtKB:P05106	Human	PMID:14681217
Molecular Function	GO:0042802	identical protein binding	ITGB3	IPI	UniProtKB:P05106	Human	PMID:22178926
Molecular Function	GO:0042802	identical protein binding	ITGB3	IPI	UniProtKB:P05106	Human	PMID:35044719
Molecular Function	GO:0031994	insulin-like growth factor I binding	ITGB3	IDA		Human	PMID:19578119
Molecular Function	GO:0005178	integrin binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:20826760
Molecular Function	GO:0005178	integrin binding	Itgb3	IPI	PR:P11688	Mouse	PMID:8601592
Molecular Function	GO:0038132	neuregulin binding	ITGB3	IDA		Human	PMID:20682778
Molecular Function	GO:0002020	protease binding	ITGB3	IDA		Human	PMID:22505472
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P35579	Human	PMID:10822899
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P01830	Human	PMID:11470407
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:11546839
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:11884718
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P43405	Human	PMID:11940607
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P54939	Human	PMID:12535520
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q01955	Human	PMID:12682293
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P48745	Human	PMID:12695522
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P35555	Human	PMID:12807887
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P05480-2	Human	PMID:14593208
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514	Human	PMID:14681217
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P35555	Human	PMID:15062093
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:15299032
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q9Y624	Human	PMID:15344881
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514	Human	PMID:15379538
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q15084	Human	PMID:15466936
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P49747	Human	PMID:16051604
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:16099422
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P18031	Human	PMID:16115959
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06935	Human	PMID:16275649
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q9Y490	Human	PMID:16546176
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:1694173
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P26039	Human	PMID:17218263
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q62101	Human	PMID:17485491
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:F5HB81	Human	PMID:18045938
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08648,UniProtKB:P21246	Human	PMID:19141530
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P12931	Human	PMID:19141530
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514	Human	PMID:19279667
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q9BX67	Human	PMID:19461049
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514-1	Human	PMID:19805198
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:20639902
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P26039	Human	PMID:21134644
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P05094	Human	PMID:2116421
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:22178926
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514-1	Human	PMID:22178926
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P26039	Human	PMID:22210111
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P78423	Human	PMID:23125415
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756	Human	PMID:24658351
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P78423	Human	PMID:24789099
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P14555:PRO_0000022750	Human	PMID:25398877
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514-1	Human	PMID:25849143
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P21333	Human	PMID:25849143
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P08514	Human	PMID:30305279
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:P06756,UniProtKB:P29965	Human	PMID:31331973
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:O95166,UniProtKB:P60520,UniProtKB:Q9BXW4,UniProtKB:Q9GZQ8,UniProtKB:Q9H492	Human	PMID:33436498
Molecular Function	GO:0005515	protein binding	ITGB3	IPI	UniProtKB:Q9Y490	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	UniProtKB:Q60857	Mouse	MGI:MGI:6101340\|PMID:29038237
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	UniProtKB:Q8K1B8	Mouse	MGI:MGI:3783912\|PMID:18278053
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	PR:P11276	Mouse	PMID:12867986
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	PR:P11688	Mouse	PMID:12867986
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	PR:Q9R0G6	Mouse	PMID:23833236
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	PR:Q5SSZ5	Mouse	PMID:27505886
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	PR:P08003	Mouse	PMID:28576878
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	RGD:1310613	Rat	PMID:1585837\|RGD:8693379
Molecular Function	GO:0005515	protein binding	Itgb3	IPI	UniProtKB:Q9JHC6	Rat	PMID:24488697\|RGD:14390054
Molecular Function	GO:0005515	protein binding	itgb3b	IPI	UniProtKB:Q6EIY7	Zfish	PMID:17626277
Molecular Function	GO:0005515	protein binding	itgb3b	IPI	UniProtKB:Q1ED36	Zfish	PMID:17626277
Molecular Function	GO:0003756	protein disulfide isomerase activity	ITGB3	IDA		Human	PMID:12204115
Molecular Function	GO:0003756	protein disulfide isomerase activity	ITGB3	IDA		Human	PMID:15466936
Molecular Function	GO:0005080	protein kinase C binding	Itgb3	IPI	UniProtKB:P20444	Mouse	MGI:MGI:5284791\|PMID:16014375
Molecular Function	GO:0043184	vascular endothelial growth factor receptor 2 binding	ITGB3	IPI	UniProtKB:P35968	Human	PMID:10022831
Cellular Component	GO:0071133	alpha9-beta1 integrin-ADAM8 complex	Itgb3	IDA		Mouse	MGI:MGI:3766172\|PMID:16995821
Cellular Component	GO:0035868	alphav-beta3 integrin-HMGB1 complex	ITGB3	IDA		Human	PMID:20826760
Cellular Component	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex	ITGB3	IDA		Human	PMID:19578119
Cellular Component	GO:0035866	alphav-beta3 integrin-PKCalpha complex	ITGB3	IDA		Human	PMID:16014375
Cellular Component	GO:0035866	alphav-beta3 integrin-PKCalpha complex	Itgb3	IDA		Mouse	MGI:MGI:5284791\|PMID:16014375
Cellular Component	GO:0016324	apical plasma membrane	Itgb3	IDA		Mouse	PMID:16216233
Cellular Component	GO:0016324	apical plasma membrane	Itgb3	IDA		Rat	PMID:21426865\|RGD:6907421
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:19234460
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:19933311
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:20563599
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:22505472
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:23023225
Cellular Component	GO:0009986	cell surface	ITGB3	HDA		Human	PMID:23382103
Cellular Component	GO:0009986	cell surface	ITGB3	HDA		Human	PMID:23658023
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0009986	cell surface	ITGB3	IDA		Human	PMID:7525578
Cellular Component	GO:0009986	cell surface	Itgb3	IDA		Mouse	MGI:MGI:5014432\|PMID:21670307
Cellular Component	GO:0009986	cell surface	Itgb3	IDA		Mouse	PMID:28576878
Cellular Component	GO:0009986	cell surface	Itgb3	IDA		Rat	PMID:11278919\|RGD:2316363
Cellular Component	GO:0005911	cell-cell junction	ITGB3	IDA		Human	PMID:19461049
Cellular Component	GO:0009897	external side of plasma membrane	Itgb3	IDA		Mouse	PMID:12900455
Cellular Component	GO:0009897	external side of plasma membrane	Itgb3	IDA		Mouse	PMID:24029230
Cellular Component	GO:0009897	external side of plasma membrane	Itgb3	IDA		Mouse	PMID:9553049
Cellular Component	GO:0070062	extracellular exosome	ITGB3	HDA		Human	PMID:20458337
Cellular Component	GO:0031527	filopodium membrane	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0005925	focal adhesion	ITGB3	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	ITGB3	IDA		Human	PMID:23023225
Cellular Component	GO:0005925	focal adhesion	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0005925	focal adhesion	Itgb3	IDA		Mouse	MGI:MGI:6101340\|PMID:29038237
Cellular Component	GO:0005925	focal adhesion	Itgb3	IDA		Rat	PMID:21426865\|RGD:6907421
Cellular Component	GO:0098978	glutamatergic synapse	ITGB3	EXP		Human	PMID:18549786
Cellular Component	GO:0098978	glutamatergic synapse	ITGB3	IDA		Human	PMID:18549786
Cellular Component	GO:0098978	glutamatergic synapse	ITGB3	IMP		Human	PMID:18549786
Cellular Component	GO:0098978	glutamatergic synapse	Itgb3	IEP		Mouse	PMID:16467530
Cellular Component	GO:0098978	glutamatergic synapse	Itgb3	IDA		Mouse	PMID:16467530
Cellular Component	GO:0098690	glycinergic synapse	Itgb3	EXP		Rat	PMID:20935643\|RGD:155230798
Cellular Component	GO:0098690	glycinergic synapse	Itgb3	IDA		Rat	PMID:20935643\|RGD:155230798
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:20826760
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:22505472
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:23726972
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:24658351
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0034683	integrin alphav-beta3 complex	ITGB3	IDA		Human	PMID:31331973
Cellular Component	GO:0008305	integrin complex	ITGB3	IDA		Human	PMID:15215180
Cellular Component	GO:0008305	integrin complex	Itgb3	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0008305	integrin complex	itgb3b	IDA		Zfish	PMID:17626277
Cellular Component	GO:0031258	lamellipodium membrane	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0042470	melanosome	ITGB3	IDA		Human	PMID:15466936
Cellular Component	GO:0016020	membrane	Itgb3	IDA		Rat	PMID:17157995\|RGD:1625132
Cellular Component	GO:0031528	microvillus membrane	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0005654	nucleoplasm	ITGB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ITGB3	IDA		Human	PMID:22027834
Cellular Component	GO:0005886	plasma membrane	ITGB3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ITGB3	IDA		Human	PMID:15466936
Cellular Component	GO:0005886	plasma membrane	ITGB3	IDA		Human	PMID:19141530
Cellular Component	GO:0032991	protein-containing complex	ITGB3	IDA		Human	PMID:15344881
Cellular Component	GO:0043235	receptor complex	ITGB3	IDA		Human	PMID:23382219
Cellular Component	GO:0032587	ruffle membrane	ITGB3	IDA		Human	PMID:25063885
Cellular Component	GO:0045202	synapse	Itgb3	IDA		Mouse	MGI:MGI:6101340\|PMID:29038237
Cellular Component	GO:0097060	synaptic membrane	Itgb3	IEP		Mouse	PMID:16467530
Cellular Component	GO:0097060	synaptic membrane	Itgb3	IDA		Mouse	PMID:16467530
Biological Process	GO:0032147	activation of protein kinase activity	ITGB3	IMP		Human	PMID:10022831
Biological Process	GO:0038027	apolipoprotein A-I-mediated signaling pathway	ITGB3	IMP		Human	PMID:23726972
Biological Process	GO:0043277	apoptotic cell clearance	ITGB3	IGI	UniProtKB:O54890	Human	PMID:20826760
Biological Process	GO:0043277	apoptotic cell clearance	Itgb3	IGI	UniProtKB:P05106	Mouse	MGI:MGI:5285150\|PMID:20826760
Biological Process	GO:0072378	blood coagulation, fibrin clot formation	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:28576878
Biological Process	GO:0033627	cell adhesion mediated by integrin	ITGB3	IDA		Human	PMID:12807887
Biological Process	GO:0007160	cell-matrix adhesion	ITGB3	IMP		Human	PMID:24658351
Biological Process	GO:0007160	cell-matrix adhesion	ITGB3	IMP		Human	PMID:7525578
Biological Process	GO:0007160	cell-matrix adhesion	Itgb3	IGI	MGI:MGI:1933825	Mouse	PMID:17099249
Biological Process	GO:0031589	cell-substrate adhesion	ITGB3	IMP		Human	PMID:19933311
Biological Process	GO:0007044	cell-substrate junction assembly	Itgb3	IDA		Mouse	PMID:12867986
Biological Process	GO:1990314	cellular response to insulin-like growth factor stimulus	Itgb3	IEP		Rat	PMID:21932665\|RGD:8693383
Biological Process	GO:0071260	cellular response to mechanical stimulus	Itgb3	IEP		Rat	PMID:12856576\|RGD:1582308
Biological Process	GO:0036120	cellular response to platelet-derived growth factor stimulus	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Itgb3	IEP		Rat	PMID:12242040\|RGD:4999478
Biological Process	GO:0007566	embryo implantation	Itgb3	IEP		Rat	PMID:16528553\|RGD:4990465
Biological Process	GO:0034113	heterotypic cell-cell adhesion	ITGB3	IMP		Human	PMID:20563599
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB3	HDA		Human	PMID:23382103
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Itgb3	EXP		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0098880	maintenance of postsynaptic specialization structure	Itgb3	IDA		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0048333	mesodermal cell differentiation	ITGB3	IEP		Human	PMID:23154389
Biological Process	GO:0050919	negative chemotaxis	ITGB3	IMP		Human	PMID:23726972
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	Itgb3	IMP		Rat	PMID:9585425\|RGD:5024926
Biological Process	GO:0010888	negative regulation of lipid storage	ITGB3	IMP		Human	PMID:15215180
Biological Process	GO:0032369	negative regulation of lipid transport	ITGB3	IMP		Human	PMID:15215180
Biological Process	GO:0050748	negative regulation of lipoprotein metabolic process	ITGB3	IMP		Human	PMID:15215180
Biological Process	GO:1905598	negative regulation of low-density lipoprotein receptor activity	ITGB3	IMP		Human	PMID:15215180
Biological Process	GO:0010745	negative regulation of macrophage derived foam cell differentiation	ITGB3	IMP		Human	PMID:15215180
Biological Process	GO:0030168	platelet activation	ITGB3	IMP		Human	PMID:15466936
Biological Process	GO:0070527	platelet aggregation	ITGB3	IMP		Human	PMID:15466936
Biological Process	GO:0070527	platelet aggregation	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:28576878
Biological Process	GO:0070527	platelet aggregation	Itgb3	IMP		Rat	PMID:17924279\|RGD:2316357
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:1900731	positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	Itgb3	IMP		Rat	PMID:17157995\|RGD:1625132
Biological Process	GO:0045766	positive regulation of angiogenesis	Itgb3	IMP		Rat	PMID:19331142\|RGD:6907423
Biological Process	GO:0045780	positive regulation of bone resorption	Itgb3	IMP		Rat	PMID:8603604\|RGD:5024929
Biological Process	GO:0033630	positive regulation of cell adhesion mediated by integrin	Itgb3	IMP		Rat	PMID:17868879\|RGD:4892652
Biological Process	GO:0030335	positive regulation of cell migration	Itgb3	IMP		Mouse	MGI:MGI:5009350\|PMID:20675382
Biological Process	GO:0001954	positive regulation of cell-matrix adhesion	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0010595	positive regulation of endothelial cell migration	ITGB3	IMP		Human	PMID:10022831
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ITGB3	IMP		Human	PMID:10022831
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Itgb3	IMP		Rat	PMID:17620283\|RGD:4892659
Biological Process	GO:0010763	positive regulation of fibroblast migration	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0010763	positive regulation of fibroblast migration	Itgb3	IMP		Rat	PMID:10869268\|RGD:5024916
Biological Process	GO:0048146	positive regulation of fibroblast proliferation	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0010628	positive regulation of gene expression	Itgb3	IMP		Mouse	MGI:MGI:5688793\|PMID:25911094
Biological Process	GO:0072126	positive regulation of glomerular mesangial cell proliferation	Itgb3	IMP		Rat	PMID:20135641\|RGD:4892623
Biological Process	GO:0002687	positive regulation of leukocyte migration	Itgb3	IMP		Rat	PMID:11705748\|RGD:2316361
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	Itgb3	IMP		Mouse	MGI:MGI:5009350\|PMID:20675382
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	ITGB3	IMP		Human	PMID:10022831
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Itgb3	IMP		Rat	PMID:12606526\|RGD:8693385
Biological Process	GO:0014911	positive regulation of smooth muscle cell migration	Itgb3	IMP		Rat	PMID:18209569\|RGD:4892635
Biological Process	GO:0048661	positive regulation of smooth muscle cell proliferation	Itgb3	IMP		Rat	PMID:19723557\|RGD:4892625
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:2000406	positive regulation of T cell migration	Itgb3	IDA		Mouse	MGI:MGI:5014432\|PMID:21670307
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Itgb3	IMP		Mouse	MGI:MGI:5688793\|PMID:25911094
Biological Process	GO:1903053	regulation of extracellular matrix organization	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Itgb3	IMP		Rat	PMID:17157995\|RGD:1625132
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Itgb3	EXP		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0150054	regulation of postsynaptic neurotransmitter receptor diffusion trapping	Itgb3	IDA		Rat	PMID:20935643\|RGD:155230798
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ITGB3	EXP		Human	PMID:18549786
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ITGB3	IDA		Human	PMID:18549786
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	ITGB3	IMP		Human	PMID:18549786
Biological Process	GO:0032880	regulation of protein localization	Itgb3	IMP		Mouse	MGI:MGI:6101340\|PMID:29038237
Biological Process	GO:0061097	regulation of protein tyrosine kinase activity	Itgb3	IMP	MGI:MGI:2175913	Mouse	PMID:22984613
Biological Process	GO:0051279	regulation of release of sequestered calcium ion into cytosol	Itgb3	IDA		Rat	PMID:7689577\|RGD:8693381
Biological Process	GO:0051611	regulation of serotonin uptake	Itgb3	IMP		Mouse	MGI:MGI:6101340\|PMID:29038237
Biological Process	GO:1901163	regulation of trophoblast cell migration	Itgb3	IMP		Mouse	PMID:15031111
Biological Process	GO:0014823	response to activity	Itgb3	IEP		Rat	PMID:12654355\|RGD:8693387
Biological Process	GO:0036119	response to platelet-derived growth factor	Itgb3	IEP		Rat	PMID:21932665\|RGD:8693383
Biological Process	GO:0009314	response to radiation	Itgb3	IEP		Rat	PMID:20159792\|RGD:2325788
Biological Process	GO:0014909	smooth muscle cell migration	ITGB3	IMP		Human	PMID:8837777
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	ITGB3	IDA		Human	PMID:24658351
Biological Process	GO:0046718	viral entry into host cell	ITGB3	IMP		Human	PMID:25063885

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.