Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITGB5
  • Mouse genes Itgb5
  • Rat genes
  • Zfish genes itgb5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itgb5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	Itgb5	IPI	UniProtKB:P43406	Mouse	MGI:MGI:5285150|PMID:20826760
Molecular Function	GO:0005178	integrin binding	Itgb5	IPI	PR:P11688	Mouse	PMID:8601592
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P48745	Human	PMID:15611078
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P06756	Human	PMID:1694173
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P12931,UniProtKB:P48357	Human	PMID:19910644
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q9BY76	Human	PMID:21397862
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q9HD67	Human	PMID:21642953
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P97479	Human	PMID:24997346
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q7Z6J6	Human	PMID:25448675
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:O76011	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:O95967	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P60409	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:P60411	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q08379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q13643	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q15323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q5JR59-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q6L8G8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q8IUG1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ITGB5	IPI	UniProtKB:Q9BYR7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Itgb5	IPI	UniProtKB:P97479	Mouse	MGI:MGI:5585527|PMID:24997346
Cellular Component	GO:0031252	cell leading edge	Itgb5	IDA		Mouse	PMID:18794329
Cellular Component	GO:0009986	cell surface	ITGB5	IDA		Human	PMID:23154389
Cellular Component	GO:0009986	cell surface	ITGB5	HDA		Human	PMID:23658023
Cellular Component	GO:0009986	cell surface	ITGB5	IDA		Human	PMID:24036928
Cellular Component	GO:0009986	cell surface	ITGB5	IDA		Human	PMID:25063885
Cellular Component	GO:0009986	cell surface	ITGB5	IDA		Human	PMID:7525578
Cellular Component	GO:0070062	extracellular exosome	ITGB5	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	ITGB5	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Itgb5	IDA		Mouse	PMID:18794329
Cellular Component	GO:0098978	glutamatergic synapse	Itgb5	IDA		Mouse	PMID:16467530
Cellular Component	GO:0098978	glutamatergic synapse	Itgb5	IEP		Mouse	PMID:16467530
Cellular Component	GO:0034684	integrin alphav-beta5 complex	ITGB5	IDA		Human	PMID:25063885
Cellular Component	GO:0034684	integrin alphav-beta5 complex	Itgb5	IDA		Mouse	MGI:MGI:5285150|PMID:20826760
Cellular Component	GO:0043235	receptor complex	ITGB5	IDA		Human	PMID:23382219
Cellular Component	GO:0097060	synaptic membrane	Itgb5	IDA		Mouse	PMID:16467530
Cellular Component	GO:0097060	synaptic membrane	Itgb5	IEP		Mouse	PMID:16467530
Biological Process	GO:0016477	cell migration	ITGB5	IMP		Human	PMID:26934001
Biological Process	GO:0007160	cell-matrix adhesion	ITGB5	IMP		Human	PMID:24036928
Biological Process	GO:0035987	endodermal cell differentiation	ITGB5	IEP		Human	PMID:23154389
Biological Process	GO:0090136	epithelial cell-cell adhesion	ITGB5	IMP		Human	PMID:24036928
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB5	IMP		Human	PMID:24036928
Biological Process	GO:0007229	integrin-mediated signaling pathway	Itgb5	IMP		Mouse	MGI:MGI:5582864|PMID:24036928
Biological Process	GO:0043149	stress fiber assembly	ITGB5	IMP		Human	PMID:24036928
Biological Process	GO:0043149	stress fiber assembly	Itgb5	IMP		Mouse	MGI:MGI:5582864|PMID:24036928
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	ITGB5	IMP		Human	PMID:24036928
Biological Process	GO:0007179	transforming growth factor beta receptor signaling pathway	Itgb5	IMP		Mouse	MGI:MGI:5582864|PMID:24036928

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern