Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITGB7
  • Mouse genes Itgb7
  • Rat genes Itgb7
  • Zfish genes itgb7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itgb7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	ITGB7	IMP		Human	PMID:23986478
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P13612	Human	PMID:14681217
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P13612	Human	PMID:1542691
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P21333	Human	PMID:17690686
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P21333	Human	PMID:19828450
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P21333	Human	PMID:21524097
Molecular Function	GO:0005515	protein binding	ITGB7	IPI	UniProtKB:P13612	Human	PMID:22232704
Cellular Component	GO:0009986	cell surface	ITGB7	IDA		Human	PMID:18308860
Cellular Component	GO:0009986	cell surface	ITGB7	IDA		Human	PMID:23986478
Cellular Component	GO:0070062	extracellular exosome	ITGB7	HDA		Human	PMID:20458337
Cellular Component	GO:0034669	integrin alpha4-beta7 complex	ITGB7	IDA		Human	PMID:18308860
Cellular Component	GO:0034669	integrin alpha4-beta7 complex	ITGB7	IDA		Human	PMID:23986478
Cellular Component	GO:0016020	membrane	ITGB7	HDA		Human	PMID:19946888
Cellular Component	GO:0043235	receptor complex	ITGB7	IDA		Human	PMID:23382219
Biological Process	GO:0007160	cell-matrix adhesion	ITGB7	IMP		Human	PMID:18308860
Biological Process	GO:0007160	cell-matrix adhesion	ITGB7	IMP		Human	PMID:23986478
Biological Process	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration	ITGB7	IMP		Human	PMID:23986478
Biological Process	GO:0034113	heterotypic cell-cell adhesion	ITGB7	IMP		Human	PMID:18308860
Biological Process	GO:0007229	integrin-mediated signaling pathway	ITGB7	IMP		Human	PMID:23986478
Biological Process	GO:0050900	leukocyte migration	Itgb7	IMP	MGI:MGI:1861953	Mouse	PMID:15484189
Biological Process	GO:0050901	leukocyte tethering or rolling	ITGB7	IMP		Human	PMID:18308860
Biological Process	GO:0043113	receptor clustering	ITGB7	IMP		Human	PMID:23986478
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	ITGB7	IMP		Human	PMID:23986478
Biological Process	GO:0072678	T cell migration	Itgb7	IMP		Mouse	PMID:23661644

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern