Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITIH4
  • Mouse genes Itih4
  • Rat genes Itih4
  • Zfish genes itih3b.1,itih3b.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itih4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ITIH4	IPI	UniProtKB:Q96KC8	Human	PMID:16271702
Molecular Function	GO:0005515	protein binding	Itih4	IPI	UniProtKB:Q61712	Mouse	MGI:MGI:3609524|PMID:16271702
Cellular Component	GO:0072562	blood microparticle	ITIH4	HDA		Human	PMID:22516433
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ITIH4	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ITIH4	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Itih4	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Itih4	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Itih4	IDA		Mouse	PMID:11803570
Cellular Component	GO:0070062	extracellular exosome	ITIH4	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	ITIH4	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	Itih4	IDA		Rat	PMID:21559420|RGD:40907059
Cellular Component	GO:0005886	plasma membrane	Itih4	IDA		Mouse	PMID:11803570
Biological Process	GO:0006953	acute-phase response	ITIH4	IEP		Human	PMID:19263524
Biological Process	GO:0034097	response to cytokine	ITIH4	IEP		Human	PMID:10486281

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern