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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Itm2b

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itm2b
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0001540amyloid-beta bindingITM2BIPIUniProtKB:P05067HumanPMID:19849849
Molecular FunctionGO:0005524ATP bindingItm2bIDAMousePMID:10679242
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:P05067HumanPMID:16027166
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:P05067-8HumanPMID:16027166
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q8TCT7HumanPMID:17965014
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q8TCT8HumanPMID:17965014
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:P56817HumanPMID:23701002
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q58DX5HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q8N205HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q8N6L0HumanPMID:25416956
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q9NRM0-1HumanPMID:31695625
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q9NRM0-2HumanPMID:31695625
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:P05067HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:P26715HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingITM2BIPIUniProtKB:Q96E17HumanPMID:32814053
Molecular FunctionGO:0005515protein bindingItm2bIPIUniProtKB:P07825RatPMID:29476059|RGD:42721991
Molecular FunctionGO:0005515protein bindingItm2bIPIUniProtKB:P07936RatPMID:29476059|RGD:42721991
Molecular FunctionGO:0005515protein bindingItm2bIPIUniProtKB:P31016RatPMID:29476059|RGD:42721991
Cellular ComponentGO:0070062extracellular exosomeITM2BHDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeITM2BHDAHumanPMID:19199708
Cellular ComponentGO:0070062extracellular exosomeITM2BHDAHumanPMID:23533145
Cellular ComponentGO:0005615extracellular spaceITM2BIDAHumanPMID:18524908
Cellular ComponentGO:0005794Golgi apparatusITM2BIDAHumanGO_REF:0000052
Cellular ComponentGO:0030660Golgi-associated vesicle membraneITM2BIDAHumanPMID:17965014
Cellular ComponentGO:0043231intracellular membrane-bounded organelleITM2BIDAHumanGO_REF:0000052
Cellular ComponentGO:0016020membraneITM2BHDAHumanPMID:19946888
Cellular ComponentGO:0031090organelle membraneITM2BIDAHumanPMID:10526337
Cellular ComponentGO:0005886plasma membraneITM2BIDAHumanPMID:19114711
Cellular ComponentGO:0005886plasma membraneITM2BIDAHumanPMID:22194595
Biological ProcessGO:0042985negative regulation of amyloid precursor protein biosynthetic processITM2BIDAHumanPMID:16027166
Biological ProcessGO:0042985negative regulation of amyloid precursor protein biosynthetic processITM2BIDAHumanPMID:18524908

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory