Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITPA
  • Mouse genes Itpa
  • Rat genes Itpa
  • Zfish genes itpa
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itpa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035870	dITP diphosphatase activity	Itpa	IMP	MGI:MGI:4942407	Mouse	PMID:20081199
Molecular Function	GO:0042802	identical protein binding	ITPA	IPI	UniProtKB:Q9BY32	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	ITPA	IPI	UniProtKB:Q9BY32	Human	PMID:32296183
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	Itpa	IDA		Mouse	PMID:7323947
Molecular Function	GO:0047429	nucleoside triphosphate diphosphatase activity	Itpa	IDA		Mouse	PMID:1914521
Cellular Component	GO:0005829	cytosol	ITPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ITPA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ITPA	IDA		Human	GO_REF:0000052
Biological Process	GO:0051276	chromosome organization	Itpa	IMP	MGI:MGI:4942407	Mouse	PMID:20081199
Biological Process	GO:0006193	ITP catabolic process	Itpa	IMP	MGI:MGI:4942407	Mouse	PMID:20081199

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern