Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ITPKA
  • Mouse genes Itpka
  • Rat genes Itpka
  • Zfish genes itpka
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Itpka

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004683	calmodulin-dependent protein kinase activity	Itpka	IDA		Rat	PMID:2176078|RGD:633124
Molecular Function	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	ITPKA	IDA		Human	PMID:12747803
Molecular Function	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	ITPKA	IDA		Human	PMID:1847047
Molecular Function	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	Itpka	IDA		Rat	PMID:2176078|RGD:633124
Molecular Function	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity	Itpka	IMP		Rat	PMID:2176078|RGD:633124
Molecular Function	GO:0031267	small GTPase binding	Itpka	IDA		Rat	PMID:19890013|RGD:8553536
Cellular Component	GO:0005856	cytoskeleton	ITPKA	IDA		Human	PMID:1847047
Cellular Component	GO:0043197	dendritic spine	Itpka	IDA		Rat	PMID:19890013|RGD:8553536
Cellular Component	GO:0098978	glutamatergic synapse	Itpka	IDA		Rat	PMID:19890013|RGD:8553536
Cellular Component	GO:0098978	glutamatergic synapse	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Itpka	IDA		Rat	PMID:19890013|RGD:8553536
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0030036	actin cytoskeleton organization	Itpka	IGI	UniProtKB:P63000	Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0030036	actin cytoskeleton organization	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0071277	cellular response to calcium ion	ITPKA	IDA		Human	PMID:12747803
Biological Process	GO:0097062	dendritic spine maintenance	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0006020	inositol metabolic process	Itpka	IMP	MGI:MGI:2152168	Mouse	PMID:10454357
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Itpka	IDA		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Itpka	IEP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0098885	modification of postsynaptic actin cytoskeleton	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	ITPKA	IDA		Human	PMID:12747803
Biological Process	GO:0046854	phosphatidylinositol phosphate biosynthetic process	ITPKA	IDA		Human	PMID:1847047
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Itpka	IMP		Rat	PMID:19890013|RGD:8553536
Biological Process	GO:0048167	regulation of synaptic plasticity	Itpka	IMP	MGI:MGI:2152168	Mouse	PMID:19890013
Biological Process	GO:0051592	response to calcium ion	ITPKA	IDA		Human	PMID:1847047

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern