Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IYD
  • Mouse genes Iyd
  • Rat genes Iyd
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Iyd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0010181	FMN binding	IYD	IDA		Human	PMID:25395621
Molecular Function	GO:0010181	FMN binding	IYD	IDA		Human	PMID:28157283
Molecular Function	GO:0010181	FMN binding	Iyd	IDA		Mouse	MGI:MGI:7260100|PMID:19777994
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	IYD	IDA		Human	PMID:15289438
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	IYD	IMP		Human	PMID:18434651
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	IYD	IDA		Human	PMID:25395621
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	IYD	IDA		Human	PMID:28157283
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	Iyd	IDA		Mouse	MGI:MGI:7260100|PMID:19777994
Molecular Function	GO:0140616	iodotyrosine deiodinase activity	Iyd	IDA		Mouse	PMID:16316988
Molecular Function	GO:0005515	protein binding	IYD	IPI	UniProtKB:Q86WT6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	IYD	IPI	UniProtKB:Q86WT6-2	Human	PMID:25910212
Cellular Component	GO:0030659	cytoplasmic vesicle membrane	IYD	IDA		Human	PMID:15289438
Cellular Component	GO:0005654	nucleoplasm	IYD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	IYD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	IYD	IDA		Human	PMID:15289438
Biological Process	GO:0042403	thyroid hormone metabolic process	IYD	IDA		Human	PMID:25395621
Biological Process	GO:0006570	tyrosine metabolic process	IYD	IDA		Human	PMID:25395621
Biological Process	GO:0006570	tyrosine metabolic process	IYD	IDA		Human	PMID:28157283
Biological Process	GO:0006570	tyrosine metabolic process	Iyd	IDA		Mouse	MGI:MGI:7260100|PMID:19777994

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern