Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes IZUMO1R
  • Mouse genes Izumo1r
  • Rat genes Izumo1r
  • Zfish genes folr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Izumo1r

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	IZUMO1R	IPI	UniProtKB:Q8IYV9	Human	PMID:24739963
Molecular Function	GO:0005515	protein binding	IZUMO1R	IPI	UniProtKB:Q8IYV9	Human	PMID:27309808
Molecular Function	GO:0005515	protein binding	Izumo1r	IPI	UniProtKB:Q9D9J7	Mouse	MGI:MGI:5568137|PMID:24739963
Molecular Function	GO:0038023	signaling receptor activity	IZUMO1R	IPI	UniProtKB:Q8IYV9	Human	PMID:24739963
Molecular Function	GO:0038023	signaling receptor activity	Izumo1r	IPI	UniProtKB:Q9D9J7	Mouse	MGI:MGI:5568137|PMID:24739963
Molecular Function	GO:0005102	signaling receptor binding	Izumo1r	IPI	UniProtKB:Q9D9J7	Mouse	MGI:MGI:5896483|PMID:27416963
Biological Process	GO:0007155	cell adhesion	Izumo1r	IMP		Mouse	MGI:MGI:5568137|PMID:24739963
Biological Process	GO:0007155	cell adhesion	Izumo1r	IDA		Mouse	MGI:MGI:5896483|PMID:27416963
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	Izumo1r	IDA		Mouse	MGI:MGI:5896483|PMID:27416963
Biological Process	GO:0007342	fusion of sperm to egg plasma membrane involved in single fertilization	Izumo1r	IMP		Mouse	MGI:MGI:5568137|PMID:24739963
Biological Process	GO:0007338	single fertilization	Izumo1r	IMP		Mouse	MGI:MGI:5568137|PMID:24739963
Biological Process	GO:0007338	single fertilization	Izumo1r	IDA		Mouse	MGI:MGI:5896483|PMID:27416963
Biological Process	GO:0035036	sperm-egg recognition	Izumo1r	IDA		Mouse	MGI:MGI:5896483|PMID:27416963
Biological Process	GO:0035036	sperm-egg recognition	Izumo1r	IMP		Mouse	MGI:MGI:5568137|PMID:24739963

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern