Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes JMJD6
  • Mouse genes Jmjd6
  • Rat genes Jmjd6
  • Zfish genes jmjd6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Jmjd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0032452	histone demethylase activity	JMJD6	IDA		Human	PMID:24498420
Molecular Function	GO:0033746	histone H3R2 demethylase activity	JMJD6	IDA		Human	PMID:17947579
Molecular Function	GO:0033749	histone H3R3 demethylase activity	JMJD6	IDA		Human	PMID:17947579
Molecular Function	GO:0033749	histone H3R3 demethylase activity	JMJD6	IDA		Human	PMID:24360279
Molecular Function	GO:0042802	identical protein binding	JMJD6	IDA		Human	PMID:17534701
Molecular Function	GO:0042802	identical protein binding	JMJD6	IPI	UniProtKB:Q6NYC1	Human	PMID:24360279
Molecular Function	GO:0042802	identical protein binding	Jmjd6	IPI	PR:Q9ERI5	Mouse	PMID:21060799
Molecular Function	GO:0005506	iron ion binding	JMJD6	IDA		Human	PMID:20679243
Molecular Function	GO:0035515	oxidative RNA demethylase activity	JMJD6	IMP		Human	PMID:24360279
Molecular Function	GO:0106140	P-TEFb complex binding	JMJD6	IDA		Human	PMID:24360279
Molecular Function	GO:0070815	peptidyl-lysine 5-dioxygenase activity	JMJD6	IDA		Human	PMID:19574390
Molecular Function	GO:0070815	peptidyl-lysine 5-dioxygenase activity	JMJD6	IDA		Human	PMID:22189873
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O95232	Human	PMID:19574390
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:P26368	Human	PMID:19574390
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q9Y383	Human	PMID:19574390
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O60885	Human	PMID:21555454
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O60885	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q01081	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q8NAV1	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q9NP64	Human	PMID:23455924
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O60563,UniProtKB:O60885,UniProtKB:P50750	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O60885	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:P50750	Human	PMID:24360279
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:P03372	Human	PMID:24498420
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q86X55	Human	PMID:24498420
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:P04637	Human	PMID:24667498
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q96NE9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q9GZZ1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:O60885	Human	PMID:29176719
Molecular Function	GO:0005515	protein binding	JMJD6	IPI	UniProtKB:Q9GZZ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Jmjd6	IPI	UniProtKB:P26369	Mouse	MGI:MGI:4940413|PMID:21300889
Molecular Function	GO:0005515	protein binding	Jmjd6	IPI	UniProtKB:Q810M6	Mouse	MGI:MGI:5608602|PMID:25369936
Molecular Function	GO:0140457	protein demethylase activity	JMJD6	IDA		Human	PMID:24498420
Molecular Function	GO:0003723	RNA binding	Jmjd6	IDA		Mouse	PMID:21060799
Molecular Function	GO:0038023	signaling receptor activity	Jmjd6	IDA		Mouse	PMID:10811223
Molecular Function	GO:0003727	single-stranded RNA binding	JMJD6	IDA		Human	PMID:20679243
Molecular Function	GO:0003727	single-stranded RNA binding	JMJD6	IDA		Human	PMID:29176719
Molecular Function	GO:0140537	transcription regulator activator activity	JMJD6	IMP		Human	PMID:21555454
Cellular Component	GO:0005737	cytoplasm	JMJD6	IDA		Human	PMID:24498420
Cellular Component	GO:0005829	cytosol	Jmjd6	IDA		Mouse	PMID:21060799
Cellular Component	GO:0005730	nucleolus	JMJD6	IDA		Human	PMID:21060799
Cellular Component	GO:0005730	nucleolus	Jmjd6	IDA		Mouse	PMID:21060799
Cellular Component	GO:0005654	nucleoplasm	JMJD6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	JMJD6	IDA		Human	PMID:21060799
Cellular Component	GO:0005654	nucleoplasm	Jmjd6	IDA		Mouse	PMID:21060799
Cellular Component	GO:0005634	nucleus	JMJD6	IDA		Human	PMID:14729065
Cellular Component	GO:0005634	nucleus	JMJD6	IDA		Human	PMID:17534701
Cellular Component	GO:0005634	nucleus	JMJD6	IMP		Human	PMID:21555454
Cellular Component	GO:0005634	nucleus	Jmjd6	IDA		Mouse	MGI:MGI:3027657|PMID:14729065
Cellular Component	GO:0005634	nucleus	Jmjd6	IDA		Mouse	PMID:21060799
Cellular Component	GO:0005886	plasma membrane	Jmjd6	IDA		Mouse	PMID:10811223
Cellular Component	GO:0005886	plasma membrane	Jmjd6	IDA		Mouse	PMID:15647754
Cellular Component	GO:1990904	ribonucleoprotein complex	Jmjd6	IDA		Mouse	PMID:21060799
Biological Process	GO:0043277	apoptotic cell clearance	Jmjd6	IMP	MGI:MGI:3043930	Mouse	PMID:14715629
Biological Process	GO:0043277	apoptotic cell clearance	Jmjd6	IMP		Mouse	PMID:15647754
Biological Process	GO:0001568	blood vessel development	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15615595
Biological Process	GO:0007166	cell surface receptor signaling pathway	Jmjd6	IDA		Mouse	PMID:10811223
Biological Process	GO:0048821	erythrocyte development	Jmjd6	IMP	MGI:MGI:3043930	Mouse	PMID:14715629
Biological Process	GO:0048821	erythrocyte development	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15345036
Biological Process	GO:0007507	heart development	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15615595
Biological Process	GO:0070078	histone H3-R2 demethylation	JMJD6	IDA		Human	PMID:17947579
Biological Process	GO:0070079	histone H4-R3 demethylation	JMJD6	IDA		Human	PMID:17947579
Biological Process	GO:0001822	kidney development	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15345036
Biological Process	GO:0030324	lung development	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15345036
Biological Process	GO:0030324	lung development	Jmjd6	IMP	MGI:MGI:2686850	Mouse	PMID:14645847
Biological Process	GO:0042116	macrophage activation	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15345036
Biological Process	GO:0035513	oxidative RNA demethylation	JMJD6	IDA		Human	PMID:24360279
Biological Process	GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	JMJD6	IDA		Human	PMID:19574390
Biological Process	GO:0006909	phagocytosis	jmjd6	IMP		Zfish	PMID:15469976
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	JMJD6	IMP		Human	PMID:21555454
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	JMJD6	IDA		Human	PMID:24360279
Biological Process	GO:0051260	protein homooligomerization	JMJD6	IDA		Human	PMID:22189873
Biological Process	GO:0051260	protein homooligomerization	JMJD6	IDA		Human	PMID:24360279
Biological Process	GO:0043654	recognition of apoptotic cell	Jmjd6	IDA		Mouse	PMID:10811223
Biological Process	GO:0043654	recognition of apoptotic cell	Jmjd6	IMP	MGI:MGI:2686850	Mouse	PMID:14645847
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	JMJD6	IMP		Human	PMID:19574390
Biological Process	GO:0048024	regulation of mRNA splicing, via spliceosome	Jmjd6	IMP		Mouse	MGI:MGI:4940413|PMID:21300889
Biological Process	GO:0060041	retina development in camera-type eye	Jmjd6	IMP	MGI:MGI:3580706	Mouse	PMID:15345036
Biological Process	GO:0002040	sprouting angiogenesis	Jmjd6	IMP		Mouse	MGI:MGI:4940413|PMID:21300889
Biological Process	GO:0033077	T cell differentiation in thymus	Jmjd6	IMP	MGI:MGI:3043930	Mouse	PMID:14715629

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern