Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kat2a

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KAT2A
- Mouse genes Kat2a
- Rat genes Kat2a
- Zfish genes kat2a
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kat2a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016407	acetyltransferase activity	Kat2a	IDA		Mouse	MGI:MGI:5619481\|PMID:17301242
Molecular Function	GO:0003682	chromatin binding	KAT2A	IDA		Human	PMID:29211711
Molecular Function	GO:0003682	chromatin binding	Kat2a	IDA		Mouse	PMID:16109736
Molecular Function	GO:0003682	chromatin binding	Kat2a	IDA		Mouse	PMID:23637336
Molecular Function	GO:0003682	chromatin binding	Kat2a	IDA		Rat	PMID:21697636\|RGD:8693753
Molecular Function	GO:0140297	DNA-binding transcription factor binding	KAT2A	IPI	UniProtKB:P28033	Human	PMID:17301242
Molecular Function	GO:0140297	DNA-binding transcription factor binding	Kat2a	IPI	UniProtKB:P28033	Mouse	MGI:MGI:5619481\|PMID:17301242
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2A	IDA		Human	PMID:10373431
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2A	IDA		Human	PMID:11564863
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2A	IDA		Human	PMID:29211711
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2A	IDA		Human	PMID:31527837
Molecular Function	GO:0004402	histone acetyltransferase activity	Kat2a	IDA		Mouse	PMID:9742083
Molecular Function	GO:0042826	histone deacetylase binding	KAT2A	IPI	UniProtKB:Q8IXJ6	Human	PMID:12887892
Molecular Function	GO:0106229	histone glutaryltransferase activity	KAT2A	IDA		Human	PMID:31542297
Molecular Function	GO:0010484	histone H3 acetyltransferase activity	KAT2A	IDA		Human	PMID:18838386
Molecular Function	GO:0010484	histone H3 acetyltransferase activity	Kat2a	IDA		Mouse	PMID:17325035
Molecular Function	GO:0043993	histone H3K18 acetyltransferase activity	Kat2a	IDA		Mouse	PMID:17325035
Molecular Function	GO:0043992	histone H3K9 acetyltransferase activity	KAT2A	IDA		Human	PMID:35995428
Molecular Function	GO:0043992	histone H3K9 acetyltransferase activity	Kat2a	IDA		Mouse	MGI:MGI:5926326\|PMID:28424240
Molecular Function	GO:0043992	histone H3K9 acetyltransferase activity	Kat2a	IDA		Mouse	PMID:17325035
Molecular Function	GO:0043997	histone H4K12 acetyltransferase activity	Kat2a	IDA		Mouse	PMID:17325035
Molecular Function	GO:0106078	histone succinyltransferase activity	KAT2A	IDA		Human	PMID:29211711
Molecular Function	GO:0008080	N-acetyltransferase activity	Kat2a	IDA		Mouse	PMID:20562830
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2A	IDA		Human	PMID:16753578
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2A	IDA		Human	PMID:23142079
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2A	IDA		Human	PMID:27796307
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2A	IDA		Human	PMID:29174768
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:O00482	Human	PMID:17664281
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q13285	Human	PMID:17664281
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q8IYH5	Human	PMID:20562830
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q01094	Human	PMID:20972224
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:O75717	Human	PMID:21725360
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q01094	Human	PMID:24502362
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:O00444	Human	PMID:27796307
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q99593	Human	PMID:29174768
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q9NY61	Human	PMID:29232376
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q01831	Human	PMID:29973595
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q01831	Human	PMID:31527837
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:P0DTC9	Human	PMID:33894414
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:P59595	Human	PMID:33894414
Molecular Function	GO:0005515	protein binding	KAT2A	IPI	UniProtKB:Q01094	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:P28033	Mouse	MGI:MGI:5619481\|PMID:17301242
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:Q80YV3	Mouse	MGI:MGI:4889165\|PMID:20946988
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:5604073\|PMID:25024434
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:Q80YV3	Mouse	MGI:MGI:3620296\|PMID:16494529
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:Q80YV3	Mouse	MGI:MGI:4462751\|PMID:20508642
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	UniProtKB:Q60591	Mouse	MGI:MGI:5926326\|PMID:28424240
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:P61965	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	MGI:MGI:3035274	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	MGI:MGI:1276116	Mouse	PMID:9742083
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:Q8CID0	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:Q8VE65	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:P45481	Mouse	PMID:9742083
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:Q99LQ1	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	PR:Q91WV0	Mouse	PMID:19103755
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	RGD:1310609	Rat	PMID:17334388\|RGD:9587456
Molecular Function	GO:0005515	protein binding	Kat2a	IPI	RGD:620925	Rat	PMID:19940161\|RGD:8693747
Molecular Function	GO:0019903	protein phosphatase binding	Kat2a	IPI	RGD:3447	Rat	PMID:15496412\|RGD:2312271
Molecular Function	GO:0003713	transcription coactivator activity	KAT2A	IDA		Human	PMID:11564863
Molecular Function	GO:0003713	transcription coactivator activity	KAT2A	IDA		Human	PMID:29211711
Molecular Function	GO:0003713	transcription coactivator activity	KAT2A	IDA		Human	PMID:29973595
Molecular Function	GO:0003713	transcription coactivator activity	KAT2A	IDA		Human	PMID:31527837
Molecular Function	GO:0140416	transcription regulator inhibitor activity	KAT2A	IDA		Human	PMID:23142079
Cellular Component	GO:0140672	ATAC complex	KAT2A	IDA		Human	PMID:19936620
Cellular Component	GO:0140672	ATAC complex	KAT2A	IDA		Human	PMID:18838386
Cellular Component	GO:0140672	ATAC complex	Kat2a	IDA		Mouse	PMID:20562830
Cellular Component	GO:0005813	centrosome	KAT2A	IDA		Human	PMID:27796307
Cellular Component	GO:0000785	chromatin	Kat2a	IDA		Rat	PMID:20130956\|RGD:9590236
Cellular Component	GO:0005615	extracellular space	KAT2A	HDA		Human	PMID:22664934
Cellular Component	GO:0000123	histone acetyltransferase complex	KAT2A	IDA		Human	PMID:29973595
Cellular Component	GO:0000123	histone acetyltransferase complex	KAT2A	IDA		Human	PMID:31527837
Cellular Component	GO:0000123	histone acetyltransferase complex	Kat2a	IDA		Mouse	PMID:9742083
Cellular Component	GO:0072686	mitotic spindle	Kat2a	IDA		Mouse	PMID:20562830
Cellular Component	GO:0005634	nucleus	KAT2A	IDA		Human	PMID:11564863
Cellular Component	GO:0005634	nucleus	KAT2A	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	KAT2A	IDA		Human	PMID:27796307
Cellular Component	GO:0005634	nucleus	KAT2A	IDA		Human	PMID:29211711
Cellular Component	GO:0005634	nucleus	Kat2a	IDA		Mouse	PMID:19103755
Cellular Component	GO:0005634	nucleus	Kat2a	IDA		Mouse	PMID:20562830
Cellular Component	GO:0005634	nucleus	Kat2a	IDA		Rat	PMID:19940161\|RGD:8693747
Cellular Component	GO:0000124	SAGA complex	KAT2A	IDA		Human	PMID:11564863
Cellular Component	GO:0000124	SAGA complex	Kat2a	IDA		Mouse	PMID:19103755
Cellular Component	GO:0033276	transcription factor TFTC complex	KAT2A	IDA		Human	PMID:10373431
Biological Process	GO:0071929	alpha-tubulin acetylation	Kat2a	IMP		Rat	PMID:20691906\|RGD:9590230
Biological Process	GO:0060349	bone morphogenesis	kat2a	IMP	ZFIN:ZDB-GENO-190426-1	Zfish	PMID:30424580
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Kat2a	IEP		Rat	PMID:15496412\|RGD:2312271
Biological Process	GO:0071356	cellular response to tumor necrosis factor	Kat2a	IEP		Rat	PMID:20130956\|RGD:9590236
Biological Process	GO:0048144	fibroblast proliferation	Kat2a	IMP	MGI:MGI:2386279	Mouse	PMID:17325035
Biological Process	GO:0048144	fibroblast proliferation	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0006094	gluconeogenesis	Kat2a	IGI	MGI:MGI:95674	Mouse	PMID:24051374
Biological Process	GO:0007507	heart development	kat2a	IMP		Zfish	PMID:29174768\|ZFIN:ZDB-PUB-171128-11
Biological Process	GO:0007507	heart development	kat2a	IMP	ZFIN:ZDB-CRISPR-180613-4	Zfish	PMID:29174768
Biological Process	GO:0007507	heart development	kat2a	IMP	ZFIN:ZDB-MRPHLNO-141120-7	Zfish	PMID:29174768
Biological Process	GO:0016573	histone acetylation	kat2a	IMP		Zfish	PMID:30424580\|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0016578	histone deubiquitination	KAT2A	IDA		Human	PMID:18206972
Biological Process	GO:0043966	histone H3 acetylation	KAT2A	IDA		Human	PMID:10373431
Biological Process	GO:0043966	histone H3 acetylation	KAT2A	IDA		Human	PMID:18838386
Biological Process	GO:0044154	histone H3-K14 acetylation	KAT2A	IDA		Human	PMID:19936620
Biological Process	GO:0016570	histone modification	Kat2a	IDA		Mouse	MGI:MGI:3709911\|PMID:17325035
Biological Process	GO:0106077	histone succinylation	KAT2A	IDA		Human	PMID:29211711
Biological Process	GO:0001701	in utero embryonic development	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0001701	in utero embryonic development	Kat2a	IMP	MGI:MGI:2386279	Mouse	PMID:17325035
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	KAT2A	IDA		Human	PMID:27796307
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	KAT2A	IDA		Human	PMID:29174768
Biological Process	GO:0048312	intracellular distribution of mitochondria	Kat2a	IMP		Rat	PMID:19542216\|RGD:9590232
Biological Process	GO:0060173	limb development	kat2a	IMP		Zfish	PMID:29174768\|ZFIN:ZDB-PUB-171128-11
Biological Process	GO:0060173	limb development	kat2a	IMP	ZFIN:ZDB-CRISPR-180613-4	Zfish	PMID:29174768
Biological Process	GO:0060173	limb development	kat2a	IMP	ZFIN:ZDB-MRPHLNO-141120-7	Zfish	PMID:29174768
Biological Process	GO:0007616	long-term memory	Kat2a	IMP		Mouse	MGI:MGI:5604073\|PMID:25024434
Biological Process	GO:0022037	metencephalon development	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0030901	midbrain development	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0035521	monoubiquitinated histone deubiquitination	KAT2A	IDA		Human	PMID:18206972
Biological Process	GO:0035522	monoubiquitinated histone H2A deubiquitination	KAT2A	IDA		Human	PMID:18206972
Biological Process	GO:0035264	multicellular organism growth	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0046600	negative regulation of centriole replication	KAT2A	IDA		Human	PMID:27796307
Biological Process	GO:0045721	negative regulation of gluconeogenesis	KAT2A	IDA		Human	PMID:16753578
Biological Process	GO:0045721	negative regulation of gluconeogenesis	KAT2A	IDA		Human	PMID:23142079
Biological Process	GO:0007399	nervous system development	Kat2a	IMP	MGI:MGI:2386279	Mouse	PMID:17325035
Biological Process	GO:0007399	nervous system development	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0001843	neural tube closure	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0106227	peptidyl-lysine glutarylation	KAT2A	IDA		Human	PMID:31542297
Biological Process	GO:2000727	positive regulation of cardiac muscle cell differentiation	Kat2a	IMP		Rat	PMID:20835911\|RGD:8693751
Biological Process	GO:0031346	positive regulation of cell projection organization	Kat2a	IMP		Rat	PMID:20691906\|RGD:9590230
Biological Process	GO:0001819	positive regulation of cytokine production	Kat2a	IMP		Mouse	MGI:MGI:5926326\|PMID:28424240
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KAT2A	IDA		Human	PMID:29973595
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KAT2A	IDA		Human	PMID:31527837
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Kat2a	IGI	MGI:MGI:95674	Mouse	PMID:24051374
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	KAT2A	IDA		Human	PMID:29211711
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kat2a	IMP		Mouse	MGI:MGI:5926326\|PMID:28424240
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kat2a	IMP		Mouse	MGI:MGI:5604073\|PMID:25024434
Biological Process	GO:1903010	regulation of bone development	Kat2a	IMP		Mouse	MGI:MGI:6377983\|PMID:30424580
Biological Process	GO:1903010	regulation of bone development	kat2a	IMP		Zfish	PMID:30424580\|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0061035	regulation of cartilage development	Kat2a	IMP		Mouse	MGI:MGI:6377983\|PMID:30424580
Biological Process	GO:0061035	regulation of cartilage development	kat2a	IMP		Zfish	PMID:30424580\|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0051726	regulation of cell cycle	KAT2A	IMP		Human	PMID:19103755
Biological Process	GO:0051726	regulation of cell cycle	Kat2a	IMP		Mouse	MGI:MGI:3835889\|PMID:19103755
Biological Process	GO:0051302	regulation of cell division	KAT2A	IDA		Human	PMID:20562830
Biological Process	GO:0051302	regulation of cell division	Kat2a	IDA		Mouse	MGI:MGI:4462728\|PMID:20562830
Biological Process	GO:0006355	regulation of DNA-templated transcription	KAT2A	IMP		Human	PMID:19936620
Biological Process	GO:0045995	regulation of embryonic development	Kat2a	IDA		Mouse	MGI:MGI:3835889\|PMID:19103755
Biological Process	GO:0031063	regulation of histone deacetylation	KAT2A	IMP		Human	PMID:20562830
Biological Process	GO:0031647	regulation of protein stability	KAT2A	IMP		Human	PMID:20562830
Biological Process	GO:0045589	regulation of regulatory T cell differentiation	Kat2a	IMP		Mouse	MGI:MGI:5926326\|PMID:28424240
Biological Process	GO:2000036	regulation of stem cell population maintenance	Kat2a	IMP		Mouse	MGI:MGI:6377803\|PMID:30270482
Biological Process	GO:0048167	regulation of synaptic plasticity	Kat2a	IMP		Mouse	MGI:MGI:5604073\|PMID:25024434
Biological Process	GO:0050863	regulation of T cell activation	Kat2a	IMP		Mouse	MGI:MGI:5926326\|PMID:28424240
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	KAT2A	IDA		Human	PMID:22055187
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	KAT2A	IDA		Human	PMID:9603525
Biological Process	GO:0090043	regulation of tubulin deacetylation	KAT2A	IMP		Human	PMID:20562830
Biological Process	GO:0031667	response to nutrient levels	Kat2a	IEP		Rat	PMID:21697636\|RGD:8693753
Biological Process	GO:0014070	response to organic cyclic compound	Kat2a	IEP		Rat	PMID:24614236\|RGD:9588318
Biological Process	GO:0001756	somitogenesis	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035
Biological Process	GO:0001756	somitogenesis	Kat2a	IGI	MGI:MGI:1276116	Mouse	PMID:15937931
Biological Process	GO:0021537	telencephalon development	Kat2a	IMP	MGI:MGI:3711317	Mouse	PMID:17325035

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.