Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KAT2B
  • Mouse genes Kat2b
  • Rat genes Kat2b
  • Zfish genes kat2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kat2b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016407	acetyltransferase activity	KAT2B	IDA		Human	PMID:15273251
Molecular Function	GO:0016407	acetyltransferase activity	KAT2B	IDA		Human	PMID:17301242
Molecular Function	GO:0016407	acetyltransferase activity	KAT2B	IDA		Human	PMID:8684459
Molecular Function	GO:0016407	acetyltransferase activity	Kat2b	EXP		Mouse	MGI:MGI:5767074|PMID:11250901
Molecular Function	GO:0003682	chromatin binding	Kat2b	IDA		Mouse	MGI:MGI:5763368|PMID:16245309
Molecular Function	GO:0003682	chromatin binding	Kat2b	IDA		Rat	PMID:20870727|RGD:9590266
Molecular Function	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity	Kat2b	IDA		Mouse	MGI:MGI:4410401|PMID:19773423
Molecular Function	GO:0140297	DNA-binding transcription factor binding	KAT2B	IPI	UniProtKB:P35680-1	Human	PMID:15509593
Molecular Function	GO:0140297	DNA-binding transcription factor binding	KAT2B	IPI	UniProtKB:P28033	Human	PMID:17301242
Molecular Function	GO:0140297	DNA-binding transcription factor binding	KAT2B	IPI	UniProtKB:Q9H6U6	Human	PMID:17505058
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2B	IDA		Human	PMID:14645221
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2B	IMP		Human	PMID:16829519
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT2B	EXP		Human	PMID:23555303
Molecular Function	GO:0004402	histone acetyltransferase activity	Kat2b	IDA		Mouse	PMID:9742083
Molecular Function	GO:0004402	histone acetyltransferase activity	Kat2b	IDA		Mouse	PMID:15992539
Molecular Function	GO:0035035	histone acetyltransferase binding	Kat2b	IPI	RGD:620036	Rat	PMID:20870727|RGD:9590266
Molecular Function	GO:0042826	histone deacetylase binding	KAT2B	IPI	UniProtKB:Q8IXJ6	Human	PMID:12887892
Molecular Function	GO:0042826	histone deacetylase binding	Kat2b	IPI	RGD:619976	Rat	PMID:24526703|RGD:9590211
Molecular Function	GO:0043992	histone H3K9 acetyltransferase activity	Kat2b	IGI	MGI:MGI:1921593	Mouse	PMID:24051374
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	KAT2B	IDA		Human	PMID:19303849
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	KAT2B	IDA		Human	PMID:19470756
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	KAT2B	IDA		Human	PMID:23932781
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Kat2b	IDA		Mouse	MGI:MGI:4410401|PMID:19773423
Molecular Function	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	Kat2b	IDA		Mouse	PMID:18250163
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2B	IDA		Human	PMID:23001180
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2B	IDA		Human	PMID:23932781
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2B	IDA		Human	PMID:26867678
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2B	IDA		Human	PMID:27796307
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	KAT2B	IDA		Human	PMID:29174768
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	Kat2b	IDA		Mouse	PMID:21084751
Molecular Function	GO:0061733	peptide-lysine-N-acetyltransferase activity	Kat2b	IGI	MGI:MGI:1927999	Mouse	PMID:21084751
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q03112	Human	PMID:11568182
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P15923-2	Human	PMID:12435739
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P03255-2	Human	PMID:12743606
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P03129	Human	PMID:12813456
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q8IXJ6	Human	PMID:12887892
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O00327	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O15516	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q99743	Human	PMID:14645221
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q12800,UniProtKB:Q13547,UniProtKB:Q86UQ8	Human	PMID:15273251
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P02299	Human	PMID:16322561
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P84040	Human	PMID:16322561
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q9EPK5	Human	PMID:16332960
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P02299	Human	PMID:16415179
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P84040	Human	PMID:16415179
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q16665	Human	PMID:16543236
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q9Y5W3	Human	PMID:16617118
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P28033	Human	PMID:17301242
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q15672	Human	PMID:18504427
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q96EB6	Human	PMID:19188449
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P22415	Human	PMID:19303849
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O60566	Human	PMID:19407811
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O88898-2	Human	PMID:22575646
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P53396	Human	PMID:23932781
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q96KQ7	Human	PMID:24492005
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O60566	Human	PMID:24825348
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O43818	Human	PMID:26867678
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:O00444	Human	PMID:27796307
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q99593	Human	PMID:29174768
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P0DTC9	Human	PMID:33894414
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P59595	Human	PMID:33894414
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q09472	Human	PMID:8684459
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q92793	Human	PMID:8684459
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q16594	Human	PMID:9674425
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P03255	Human	PMID:9687513
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:P03255-2	Human	PMID:9687513
Molecular Function	GO:0005515	protein binding	KAT2B	IPI	UniProtKB:Q92793	Human	PMID:9687513
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	UniProtKB:Q505F1	Mouse	MGI:MGI:5919259|PMID:17187077
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	UniProtKB:Q9QZB6	Mouse	MGI:MGI:5645210|PMID:12709428
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	UniProtKB:Q505F1	Mouse	MGI:MGI:5284760|PMID:18682553
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	PR:P27889	Mouse	PMID:15647252
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	PR:Q8VIM5	Mouse	PMID:15601857
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	PR:P45481	Mouse	PMID:9742083
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	MGI:MGI:1276116	Mouse	PMID:9742083
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	PR:P27889	Mouse	PMID:15509593
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	PR:Q3U182	Mouse	PMID:24051374
Molecular Function	GO:0005515	protein binding	Kat2b	IPI	RGD:1562627	Rat	PMID:18042454|RGD:9590276
Molecular Function	GO:0019901	protein kinase binding	Kat2b	IPI	UniProtKB:P97377	Mouse	MGI:MGI:4410401|PMID:19773423
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Kat2b	IDA		Mouse	PMID:21402781
Molecular Function	GO:0003713	transcription coactivator activity	KAT2B	IDA		Human	PMID:12435739
Molecular Function	GO:0003713	transcription coactivator activity	KAT2B	IDA		Human	PMID:14645221
Molecular Function	GO:0003713	transcription coactivator activity	Kat2b	IDA		Mouse	PMID:15509593
Molecular Function	GO:0003713	transcription coactivator activity	Kat2b	IDA		Mouse	PMID:15647252
Molecular Function	GO:0003712	transcription coregulator activity	KAT2B	IPI	UniProtKB:Q09472	Human	PMID:8684459
Molecular Function	GO:0003712	transcription coregulator activity	KAT2B	IPI	UniProtKB:Q92793	Human	PMID:8684459
Molecular Function	GO:0140537	transcription regulator activator activity	Kat2b	IDA		Mouse	PMID:21084751
Molecular Function	GO:0140537	transcription regulator activator activity	Kat2b	IGI	MGI:MGI:1927999	Mouse	PMID:21084751
Cellular Component	GO:0031672	A band	Kat2b	IDA		Mouse	PMID:18250163
Cellular Component	GO:0042641	actomyosin	Kat2b	IDA		Mouse	PMID:18250163
Cellular Component	GO:0140672	ATAC complex	KAT2B	IDA		Human	PMID:18838386
Cellular Component	GO:0140672	ATAC complex	Kat2b	IDA		Mouse	MGI:MGI:6827473|PMID:19936620
Cellular Component	GO:0005813	centrosome	KAT2B	IDA		Human	PMID:27796307
Cellular Component	GO:0000785	chromatin	Kat2b	IDA		Rat	PMID:20870727|RGD:9590266
Cellular Component	GO:0005829	cytosol	KAT2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Kat2b	IDA		Rat	PMID:22859492|RGD:8693759
Cellular Component	GO:0000123	histone acetyltransferase complex	Kat2b	IDA		Mouse	PMID:9742083
Cellular Component	GO:0031674	I band	Kat2b	IDA		Mouse	PMID:18250163
Cellular Component	GO:0000776	kinetochore	Kat2b	IDA		Mouse	PMID:14519686
Cellular Component	GO:0005654	nucleoplasm	KAT2B	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	KAT2B	IDA		Human	PMID:25593309
Cellular Component	GO:0005634	nucleus	KAT2B	IDA		Human	PMID:27796307
Cellular Component	GO:0005634	nucleus	Kat2b	IDA		Mouse	MGI:MGI:4410401|PMID:19773423
Cellular Component	GO:0005634	nucleus	Kat2b	IDA		Mouse	PMID:21084751
Cellular Component	GO:0005634	nucleus	Kat2b	IDA		Mouse	PMID:18250163
Cellular Component	GO:0005634	nucleus	Kat2b	IDA		Mouse	PMID:15509593
Cellular Component	GO:0005634	nucleus	Kat2b	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0032991	protein-containing complex	KAT2B	IDA		Human	PMID:15273251
Cellular Component	GO:0032991	protein-containing complex	KAT2B	IPI	UniProtKB:P52732,UniProtKB:P98175,UniProtKB:Q5VVJ2	Human	PMID:17707232
Biological Process	GO:0060349	bone morphogenesis	kat2b	IMP	ZFIN:ZDB-GENO-190426-2	Zfish	PMID:30424580
Biological Process	GO:0032869	cellular response to insulin stimulus	KAT2B	IDA		Human	PMID:19303849
Biological Process	GO:0034599	cellular response to oxidative stress	Kat2b	IEP		Rat	PMID:18945670|RGD:2306468
Biological Process	GO:0071374	cellular response to parathyroid hormone stimulus	Kat2b	IEP		Rat	PMID:20870727|RGD:9590266
Biological Process	GO:0006338	chromatin remodeling	KAT2B	IDA		Human	PMID:17707232
Biological Process	GO:0006094	gluconeogenesis	Kat2b	IGI	MGI:MGI:2155884	Mouse	PMID:24051374
Biological Process	GO:0006094	gluconeogenesis	Kat2b	IGI	MGI:MGI:95674	Mouse	PMID:24051374
Biological Process	GO:0007507	heart development	kat2b	IMP		Zfish	PMID:29174768|ZFIN:ZDB-PUB-171128-11
Biological Process	GO:0007507	heart development	kat2b	IMP	ZFIN:ZDB-MRPHLNO-180613-2	Zfish	PMID:29174768
Biological Process	GO:0007507	heart development	kat2b	IMP	ZFIN:ZDB-CRISPR-180613-5	Zfish	PMID:29174768
Biological Process	GO:0016573	histone acetylation	kat2b	IMP		Zfish	PMID:30424580|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0043966	histone H3 acetylation	KAT2B	IDA		Human	PMID:18838386
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:23932781
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:27796307
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:29174768
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	Kat2b	IMP		Mouse	MGI:MGI:4410401|PMID:19773423
Biological Process	GO:0018393	internal peptidyl-lysine acetylation	Kat2b	IGI	MGI:MGI:1921593	Mouse	PMID:24051374
Biological Process	GO:0060173	limb development	kat2b	IMP		Zfish	PMID:29174768|ZFIN:ZDB-PUB-171128-11
Biological Process	GO:0060173	limb development	kat2b	IMP	ZFIN:ZDB-CRISPR-180613-5	Zfish	PMID:29174768
Biological Process	GO:0060173	limb development	kat2b	IMP	ZFIN:ZDB-MRPHLNO-180613-2	Zfish	PMID:29174768
Biological Process	GO:0007613	memory	Kat2b	IEP		Rat	PMID:20811339|RGD:9588306
Biological Process	GO:0018076	N-terminal peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:12435739
Biological Process	GO:0008285	negative regulation of cell population proliferation	KAT2B	IDA		Human	PMID:8684459
Biological Process	GO:0046600	negative regulation of centriole replication	KAT2B	IDA		Human	PMID:27796307
Biological Process	GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	Kat2b	IDA		Mouse	MGI:MGI:4410401|PMID:19773423
Biological Process	GO:2000233	negative regulation of rRNA processing	KAT2B	IDA		Human	PMID:26867678
Biological Process	GO:0018394	peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:19303849
Biological Process	GO:0018394	peptidyl-lysine acetylation	KAT2B	IDA		Human	PMID:19470756
Biological Process	GO:1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	KAT2B	IDA		Human	PMID:23001180
Biological Process	GO:0035563	positive regulation of chromatin binding	Kat2b	IMP		Rat	PMID:20870727|RGD:9590266
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Kat2b	IDA		Mouse	PMID:15509593
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Kat2b	IDA		Mouse	PMID:15647252
Biological Process	GO:0045723	positive regulation of fatty acid biosynthetic process	KAT2B	IDA		Human	PMID:23932781
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Kat2b	IGI	MGI:MGI:2155884	Mouse	PMID:24051374
Biological Process	GO:0045722	positive regulation of gluconeogenesis	Kat2b	IGI	MGI:MGI:95674	Mouse	PMID:24051374
Biological Process	GO:0045821	positive regulation of glycolytic process	Kat2b	IDA		Mouse	PMID:21084751
Biological Process	GO:2000617	positive regulation of histone H3-K9 acetylation	Kat2b	IMP		Rat	PMID:20094059|RGD:7364756
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Kat2b	IDA		Mouse	PMID:21084751
Biological Process	GO:0010976	positive regulation of neuron projection development	Kat2b	IMP		Rat	PMID:20094059|RGD:7364756
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	KAT2B	IDA		Human	PMID:19470756
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kat2b	IGI	MGI:MGI:2137495	Mouse	PMID:15601857
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kat2b	IMP		Rat	PMID:20870727|RGD:9590266
Biological Process	GO:0000432	positive regulation of transcription from RNA polymerase II promoter by glucose	Kat2b	IDA		Mouse	PMID:21084751
Biological Process	GO:0006473	protein acetylation	KAT2B	IDA		Human	PMID:15273251
Biological Process	GO:0006473	protein acetylation	KAT2B	IDA		Human	PMID:26867678
Biological Process	GO:0006473	protein acetylation	Kat2b	IMP		Rat	PMID:22859492|RGD:8693759
Biological Process	GO:1903010	regulation of bone development	kat2b	IMP		Zfish	PMID:30424580|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0061035	regulation of cartilage development	kat2b	IMP		Zfish	PMID:30424580|ZFIN:ZDB-PUB-181115-3
Biological Process	GO:0010835	regulation of protein ADP-ribosylation	KAT2B	IDA		Human	PMID:19470756
Biological Process	GO:0042311	vasodilation	Kat2b	IDA		Rat	PMID:22859492|RGD:8693759

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern