Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KAT6A
  • Mouse genes Kat6a
  • Rat genes Kat6a
  • Zfish genes kat6a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kat6a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Kat6a	IGI	MGI:MGI:1922816	Mouse	PMID:22921202
Molecular Function	GO:0003677	DNA binding	KAT6A	IDA		Human	PMID:17925393
Molecular Function	GO:0140297	DNA-binding transcription factor binding	KAT6A	IPI	UniProtKB:Q01196-1	Human	PMID:11742995
Molecular Function	GO:0004402	histone acetyltransferase activity	KAT6A	IDA		Human	PMID:17925393
Molecular Function	GO:0004402	histone acetyltransferase activity	kat6a	IMP		Zfish	PMID:15128673
Molecular Function	GO:0004402	histone acetyltransferase activity	kat6a	IDA		Zfish	PMID:18469222
Molecular Function	GO:0036408	histone H3K14 acetyltransferase activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0036408	histone H3K14 acetyltransferase activity	KAT6A	IDA		Human	PMID:16387653
Molecular Function	GO:0043992	histone H3K9 acetyltransferase activity	Kat6a	IMP	MGI:MGI:4418468	Mouse	PMID:22921202
Molecular Function	GO:0043997	histone H4K12 acetyltransferase activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0046972	histone H4K16 acetyltransferase activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0043995	histone H4K5 acetyltransferase activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0043996	histone H4K8 acetyltransferase activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0005515	protein binding	KAT6A	IPI	UniProtKB:Q13950	Human	PMID:11965546
Molecular Function	GO:0005515	protein binding	KAT6A	IPI	UniProtKB:P61964	Human	PMID:20581860
Molecular Function	GO:0005515	protein binding	KAT6A	IPI	UniProtKB:Q03164:PRO_0000390950	Human	PMID:20581860
Molecular Function	GO:0005515	protein binding	KAT6A	IPI	UniProtKB:P04637	Human	PMID:23431171
Molecular Function	GO:0005515	protein binding	KAT6A	IPI	UniProtKB:P29590-4	Human	PMID:23431171
Molecular Function	GO:0005515	protein binding	Kat6a	IPI	PR:P17433	Mouse	PMID:16702405
Molecular Function	GO:0005515	protein binding	Kat6a	IPI	RGD:628633	Rat	PMID:17083329|RGD:2312274
Molecular Function	GO:0003713	transcription coactivator activity	KAT6A	IDA		Human	PMID:11742995
Molecular Function	GO:0003713	transcription coactivator activity	KAT6A	IDA		Human	PMID:11965546
Molecular Function	GO:0008270	zinc ion binding	KAT6A	IDA		Human	PMID:17925393
Cellular Component	GO:0000785	chromatin	kat6a	IDA		Zfish	PMID:18469222
Cellular Component	GO:0005829	cytosol	KAT6A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070776	MOZ/MORF histone acetyltransferase complex	KAT6A	IDA		Human	PMID:18794358
Cellular Component	GO:0070776	MOZ/MORF histone acetyltransferase complex	KAT6A	IDA		Human	PMID:16387653
Cellular Component	GO:0016607	nuclear speck	KAT6A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	KAT6A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	KAT6A	IDA		Human	PMID:11742995
Cellular Component	GO:0005634	nucleus	KAT6A	IDA		Human	PMID:18794358
Cellular Component	GO:0005634	nucleus	Kat6a	IDA		Mouse	PMID:10716735
Cellular Component	GO:0005634	nucleus	Kat6a	IDA		Rat	PMID:17083329|RGD:2312274
Cellular Component	GO:0016605	PML body	KAT6A	IDA		Human	PMID:23431171
Biological Process	GO:0009952	anterior/posterior pattern specification	kat6a	IGI	ZFIN:ZDB-MRPHLNO-051221-3,ZFIN:ZDB-MRPHLNO-080925-1	Zfish	PMID:18469222
Biological Process	GO:0035909	aorta morphogenesis	Kat6a	IMP	MGI:MGI:4418468	Mouse	PMID:22921202
Biological Process	GO:0035909	aorta morphogenesis	Kat6a	IGI	MGI:MGI:98493	Mouse	PMID:22921202
Biological Process	GO:0001502	cartilage condensation	kat6a	IMP	ZFIN:ZDB-GENO-040601-1	Zfish	PMID:15128673
Biological Process	GO:0051216	cartilage development	kat6a	IGI	ZFIN:ZDB-GENO-100517-6,ZFIN:ZDB-MRPHLNO-051221-3	Zfish	PMID:16759393
Biological Process	GO:0051216	cartilage development	kat6a	IMP	ZFIN:ZDB-GENO-040601-1	Zfish	PMID:16774997
Biological Process	GO:0090398	cellular senescence	KAT6A	IMP		Human	PMID:23431171
Biological Process	GO:0010172	embryonic body morphogenesis	kat6a	IMP	ZFIN:ZDB-GENO-040601-1	Zfish	PMID:15128673
Biological Process	GO:0035162	embryonic hemopoiesis	Kat6a	IMP		Mouse	PMID:16702405
Biological Process	GO:0009880	embryonic pattern specification	kat6a	IMP	ZFIN:ZDB-MRPHLNO-051221-3	Zfish	PMID:16759393
Biological Process	GO:0048706	embryonic skeletal system development	kat6a	IMP	ZFIN:ZDB-GENO-040601-1	Zfish	PMID:16774997
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	kat6a	IGI	ZFIN:ZDB-GENO-090624-3,ZFIN:ZDB-MRPHLNO-051221-6	Zfish	PMID:15128673
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	kat6a	IMP	ZFIN:ZDB-GENO-090624-3	Zfish	PMID:15128673
Biological Process	GO:0060325	face morphogenesis	Kat6a	IMP	MGI:MGI:4418468	Mouse	PMID:22921202
Biological Process	GO:0060325	face morphogenesis	Kat6a	IGI	MGI:MGI:98493	Mouse	PMID:22921202
Biological Process	GO:0003007	heart morphogenesis	Kat6a	IMP	MGI:MGI:4418468	Mouse	PMID:22921202
Biological Process	GO:0003007	heart morphogenesis	Kat6a	IGI	MGI:MGI:98493	Mouse	PMID:22921202
Biological Process	GO:0016570	histone modification	Kat6a	IMP	MGI:MGI:4418468	Mouse	MGI:MGI:5442217|PMID:22921202
Biological Process	GO:0030099	myeloid cell differentiation	KAT6A	IDA		Human	PMID:11742995
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	Kat6a	IMP	MGI:MGI:4418468	Mouse	PMID:22921202
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	KAT6A	IDA		Human	PMID:11742995
Biological Process	GO:0014036	neural crest cell fate specification	kat6a	IMP	ZFIN:ZDB-GENO-040601-1	Zfish	PMID:16774997
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KAT6A	IDA		Human	PMID:11742995
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KAT6A	IDA		Human	PMID:11965546
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KAT6A	IDA		Human	PMID:18794358
Biological Process	GO:0010628	positive regulation of gene expression	Kat6a	IDA		Rat	PMID:17083329|RGD:2312274
Biological Process	GO:0006473	protein acetylation	KAT6A	IDA		Human	PMID:23431171
Biological Process	GO:0006355	regulation of DNA-templated transcription	KAT6A	IDA		Human	PMID:18794358
Biological Process	GO:0035019	somatic stem cell population maintenance	Kat6a	IMP	MGI:MGI:3626344	Mouse	PMID:16651658
Biological Process	GO:0035019	somatic stem cell population maintenance	Kat6a	IMP		Mouse	PMID:16702405

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern