Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KATNA1
  • Mouse genes Katna1
  • Rat genes Katna1
  • Zfish genes katna1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Katna1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016887	ATP hydrolysis activity	Katna1	IDA		Mouse	PMID:10445032
Molecular Function	GO:0070840	dynein complex binding	Katna1	IDA		Mouse	PMID:16203747
Molecular Function	GO:0008017	microtubule binding	KATNA1	IDA		Human	PMID:10751153
Molecular Function	GO:0008568	microtubule severing ATPase activity	KATNA1	IDA		Human	PMID:10751153
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q13618	Human	PMID:19261606
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9P2K6	Human	PMID:19261606
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q08AD1	Human	PMID:24486153
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9P1Y5	Human	PMID:24486153
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9BVA0	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9H079	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9BVA0	Human	PMID:26929214
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9H079	Human	PMID:26929214
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9BVA0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KATNA1	IPI	UniProtKB:Q9H079	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Katna1	IPI	UniProtKB:Q8BG40	Mouse	MGI:MGI:5476424|PMID:22325007
Molecular Function	GO:0005515	protein binding	Katna1	IPI	UniProtKB:Q8BG40	Mouse	MGI:MGI:5905207|PMID:28436967
Molecular Function	GO:0005515	protein binding	Katna1	IPI	PR:Q8BG40	Mouse	PMID:16203747
Molecular Function	GO:0005515	protein binding	Katna1	IPI	PR:Q9ERR1	Mouse	PMID:16203747
Molecular Function	GO:0046982	protein heterodimerization activity	KATNA1	IPI	UniProtKB:Q9BVA0	Human	PMID:10751153
Cellular Component	GO:0030424	axon	Katna1	IDA		Mouse	PMID:15944385
Cellular Component	GO:0030424	axon	Katna1	IDA		Rat	PMID:15944385|RGD:2316489
Cellular Component	GO:0005813	centrosome	Katna1	IDA		Mouse	PMID:16203747
Cellular Component	GO:0005737	cytoplasm	KATNA1	IDA		Human	PMID:19261606
Cellular Component	GO:0005737	cytoplasm	KATNA1	IDA		Human	PMID:26929214
Cellular Component	GO:0030426	growth cone	Katna1	IDA		Rat	PMID:15944385|RGD:2316489
Cellular Component	GO:0008352	katanin complex	KATNA1	IPI		Human	PMID:26929214
Cellular Component	GO:0005811	lipid droplet	Katna1	IDA		Mouse	PMID:10445032
Cellular Component	GO:0030496	midbody	KATNA1	IDA		Human	PMID:19261606
Cellular Component	GO:0097431	mitotic spindle pole	KATNA1	IDA		Human	PMID:26929214
Cellular Component	GO:0043025	neuronal cell body	Katna1	IDA		Rat	PMID:15944385|RGD:2316489
Cellular Component	GO:0005634	nucleus	Katna1	IDA		Mouse	PMID:10445032
Cellular Component	GO:0005886	plasma membrane	Katna1	IDA		Mouse	PMID:10445032
Cellular Component	GO:0005819	spindle	KATNA1	IDA		Human	PMID:19261606
Cellular Component	GO:0000922	spindle pole	KATNA1	IDA		Human	PMID:10751153
Cellular Component	GO:0000922	spindle pole	KATNA1	IDA		Human	PMID:19261606
Biological Process	GO:0048675	axon extension	katna1	IMP	ZFIN:ZDB-MRPHLNO-101108-12	Zfish	PMID:20829563
Biological Process	GO:0048675	axon extension	katna1	IGI	ZFIN:ZDB-MRPHLNO-061004-1,ZFIN:ZDB-MRPHLNO-101108-12	Zfish	PMID:20829563
Biological Process	GO:0031122	cytoplasmic microtubule organization	KATNA1	IDA		Human	PMID:26929214
Biological Process	GO:0031122	cytoplasmic microtubule organization	Katna1	IDA		Mouse	PMID:15944385
Biological Process	GO:0031122	cytoplasmic microtubule organization	katna1	IMP	ZFIN:ZDB-MRPHLNO-101108-13	Zfish	PMID:20829563
Biological Process	GO:0001578	microtubule bundle formation	Katna1	IGI	MGI:MGI:2683461	Mouse	PMID:20530212
Biological Process	GO:0051013	microtubule severing	Katna1	IGI	MGI:MGI:2683461	Mouse	PMID:20530212
Biological Process	GO:0051013	microtubule severing	Katna1	IDA		Rat	PMID:15944385|RGD:2316489
Biological Process	GO:0010977	negative regulation of neuron projection development	Katna1	IDA		Rat	PMID:15944385|RGD:2316489
Biological Process	GO:0001764	neuron migration	Katna1	IMP		Mouse	PMID:16203747
Biological Process	GO:0008104	protein localization	Katna1	IPI	UniProtKB:P54310	Mouse	PMID:10445032

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern