Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcna4

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNA4
- Mouse genes Kcna4
- Rat genes Kcna4
- Zfish genes kcna4
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcna4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005216	monoatomic ion channel activity	Kcna4	IDA		Rat	PMID:2384173\|RGD:69869
Molecular Function	GO:0005267	potassium channel activity	Kcna4	IDA		Rat	PMID:2384173\|RGD:69869
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P31016	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P78352	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:Q62936	Human	PMID:11937501
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P21673	Human	PMID:16169070
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:Q8N5I3	Human	PMID:19968958
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P21673	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P78352	Human	PMID:7477295
Molecular Function	GO:0005515	protein binding	KCNA4	IPI	UniProtKB:P31016	Human	PMID:9786987
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:5508283\|PMID:12067714
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:4359331\|PMID:19455133
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:Q62108	Mouse	MGI:MGI:6092779\|PMID:28671696
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:P78352	Rat	PMID:10433268\|RGD:68848
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:Q8K4Y5	Rat	PMID:16504945\|RGD:8554700
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	RGD:2956	Rat	PMID:21943416\|RGD:7242916
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	RGD:621383	Rat	PMID:21943416\|RGD:7242916
Molecular Function	GO:0005515	protein binding	Kcna4	IPI	UniProtKB:P78352	Rat	PMID:7477295\|RGD:8554588
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcna4	IMP		Mouse	PMID:22615428
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcna4	IDA		Mouse	PMID:22615428
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNA4	IMP		Human	PMID:19912772
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNA4	IDA		Human	PMID:8495559
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcna4	IDA		Rat	PMID:2384173\|RGD:69869
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcna4	IMP		Rat	PMID:2555158\|RGD:69870
Cellular Component	GO:0032279	asymmetric synapse	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0030424	axon	Kcna4	IDA		Rat	PMID:8361540\|RGD:10047358
Cellular Component	GO:0043194	axon initial segment	Kcna4	IDA		Mouse	PMID:18509034
Cellular Component	GO:0009986	cell surface	Kcna4	IDA		Rat	PMID:21943416\|RGD:7242916
Cellular Component	GO:0009986	cell surface	Kcna4	IDA		Rat	PMID:21943417\|RGD:12910700
Cellular Component	GO:0043198	dendritic shaft	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0043197	dendritic spine	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0005783	endoplasmic reticulum	Kcna4	IDA		Rat	PMID:21943416\|RGD:7242916
Cellular Component	GO:0005783	endoplasmic reticulum	Kcna4	IDA		Rat	PMID:21943417\|RGD:12910700
Cellular Component	GO:0098978	glutamatergic synapse	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0016020	membrane	Kcna4	IDA		Mouse	PMID:18603586
Cellular Component	GO:0016020	membrane	Kcna4	IDA		Rat	PMID:8361540\|RGD:10047358
Cellular Component	GO:0005886	plasma membrane	KCNA4	IMP		Human	PMID:19912772
Cellular Component	GO:0005886	plasma membrane	KCNA4	IMP		Human	PMID:8495559
Cellular Component	GO:0005886	plasma membrane	Kcna4	IDA		Rat	PMID:10330244\|RGD:628470
Cellular Component	GO:0005886	plasma membrane	Kcna4	IMP		Rat	PMID:2555158\|RGD:69870
Cellular Component	GO:0045211	postsynaptic membrane	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0042734	presynaptic membrane	Kcna4	IDA		Rat	PMID:14615029\|RGD:12907553
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNA4	IMP		Human	PMID:8495559
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcna4	IDA		Rat	PMID:9334400\|RGD:10047182
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Kcna4	IMP		Mouse	MGI:MGI:5507792\|PMID:22615428
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNA4	IMP		Human	PMID:19912772
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNA4	IDA		Human	PMID:8495559
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcna4	IMP		Rat	PMID:2555158\|RGD:69870
Biological Process	GO:0099505	regulation of presynaptic membrane potential	Kcna4	IMP		Mouse	MGI:MGI:5507792\|PMID:22615428

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.