Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNA6
  • Mouse genes Kcna6
  • Rat genes Kcna6
  • Zfish genes kcna6a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcna6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNA6	IDA		Human	PMID:2347305
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcna6	IDA		Rat	PMID:15618540|RGD:10047274
Molecular Function	GO:0005515	protein binding	KCNA6	IPI	UniProtKB:Q9UPQ8	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KCNA6	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kcna6	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Cellular Component	GO:0030424	axon	Kcna6	IDA		Mouse	MGI:MGI:4947004|PMID:21233214
Cellular Component	GO:0043679	axon terminus	Kcna6	IDA		Mouse	MGI:MGI:4947004|PMID:21233214
Cellular Component	GO:0005829	cytosol	KCNA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	KCNA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KCNA6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KCNA6	IMP		Human	PMID:2347305
Cellular Component	GO:0005886	plasma membrane	Kcna6	IMP		Rat	PMID:15618540|RGD:10047274
Cellular Component	GO:0034705	potassium channel complex	Kcna6	IDA		Rat	PMID:9334400|RGD:10047182
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcna6	IDA		Rat	PMID:15618540|RGD:10047274
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNA6	IDA		Human	PMID:2347305
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcna6	IDA		Rat	PMID:15618540|RGD:10047274

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern