Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNB1
- Mouse genes Kcnb1
- Rat genes Kcnb1
- Zfish genes kcnb1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNB1	IDA		Human	PMID:19074135
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNB1	IDA		Human	PMID:19223394
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IMP		Mouse	MGI:MGI:5634878\|PMID:24494598
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IMP		Mouse	MGI:MGI:3770494\|PMID:17767909
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Mouse	MGI:MGI:5508719\|PMID:22056818
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:19219384\|RGD:7243947
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:19690160\|RGD:10047295
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:8189205\|RGD:2303541
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:8980147\|RGD:10047188
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IDA		Rat	PMID:9305895\|RGD:737625
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnb1	IMP		Rat	PMID:9545040\|RGD:2303542
Molecular Function	GO:0015271	outward rectifier potassium channel activity	Kcnb1	IMP		Rat	PMID:12127166\|RGD:1581351
Molecular Function	GO:0005515	protein binding	KCNB1	IPI	UniProtKB:Q96KK3	Human	PMID:10484328
Molecular Function	GO:0005515	protein binding	KCNB1	IPI	UniProtKB:Q8TAE7	Human	PMID:11852086
Molecular Function	GO:0005515	protein binding	KCNB1	IPI	UniProtKB:Q8TDN2	Human	PMID:34535971
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:Q80ZD8	Mouse	MGI:MGI:5508719\|PMID:22056818
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P22460	Mouse	PMID:8576199
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:Q9JJV7	Rat	PMID:12954870\|RGD:10047250
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	RGD:3728	Rat	PMID:16478442\|RGD:1581072
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P32851	Rat	PMID:17301173\|RGD:10047384
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P32851	Rat	PMID:18167541\|RGD:10047360
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P15383	Rat	PMID:19219384\|RGD:7243947
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P63161	Rat	PMID:19219384\|RGD:7243947
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P63045	Rat	PMID:19690160\|RGD:10047295
Molecular Function	GO:0005515	protein binding	Kcnb1	IPI	UniProtKB:P32851	Rat	PMID:20484665\|RGD:10047179
Molecular Function	GO:0046982	protein heterodimerization activity	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Molecular Function	GO:0000149	SNARE binding	Kcnb1	IPI	UniProtKB:P32851	Rat	PMID:19077057\|RGD:10047372
Molecular Function	GO:0000149	SNARE binding	Kcnb1	IPI	UniProtKB:P60881	Rat	PMID:19077057\|RGD:10047372
Molecular Function	GO:0000149	SNARE binding	Kcnb1	IPI	UniProtKB:P63045	Rat	PMID:19077057\|RGD:10047372
Molecular Function	GO:0044325	transmembrane transporter binding	KCNB1	IPI	UniProtKB:Q8TDN1	Human	PMID:19074135
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnb1	IPI	UniProtKB:Q63099	Rat	PMID:20202934\|RGD:10047337
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnb1	IDA		Rat	PMID:15046870\|RGD:8553483
Cellular Component	GO:0016324	apical plasma membrane	Kcnb1	IMP		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0030424	axon	Kcnb1	IDA		Rat	PMID:19014551\|RGD:10047314
Cellular Component	GO:0030424	axon	Kcnb1	IDA		Rat	PMID:22648171\|RGD:10047382
Cellular Component	GO:0009986	cell surface	Kcnb1	IDA		Rat	PMID:21943417\|RGD:12910700
Cellular Component	GO:0009986	cell surface	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0098981	cholinergic synapse	Kcnb1	IDA		Rat	PMID:14608003\|RGD:2303543
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Mouse	MGI:MGI:5508719\|PMID:22056818
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:19014551\|RGD:10047314
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:22648171\|RGD:10047382
Cellular Component	GO:0030425	dendrite	Kcnb1	IDA		Rat	PMID:8463836\|RGD:2303537
Cellular Component	GO:0032590	dendrite membrane	Kcnb1	IDA		Rat	PMID:14608003\|RGD:2303543
Cellular Component	GO:0005783	endoplasmic reticulum	Kcnb1	IDA		Rat	PMID:21943417\|RGD:12910700
Cellular Component	GO:0016328	lateral plasma membrane	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0016020	membrane	Kcnb1	IDA		Rat	PMID:8189205\|RGD:2303541
Cellular Component	GO:0043025	neuronal cell body	Kcnb1	IDA		Rat	PMID:8463836\|RGD:2303537
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Mouse	MGI:MGI:5508719\|PMID:22056818
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:14608003\|RGD:2303543
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:19014551\|RGD:10047314
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:22648171\|RGD:10047382
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:24355600\|RGD:126908004
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0043204	perikaryon	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0005886	plasma membrane	KCNB1	IDA		Human	PMID:19074135
Cellular Component	GO:0005886	plasma membrane	KCNB1	IDA		Human	PMID:19223394
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Mouse	MGI:MGI:3770494\|PMID:17767909
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:17301173\|RGD:10047384
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:18167541\|RGD:10047360
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:19219384\|RGD:7243947
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:19690160\|RGD:10047295
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:8980147\|RGD:10047188
Cellular Component	GO:0005886	plasma membrane	Kcnb1	IDA		Rat	PMID:9305895\|RGD:737625
Cellular Component	GO:0045211	postsynaptic membrane	Kcnb1	IDA		Rat	PMID:14608003\|RGD:2303543
Cellular Component	GO:0099634	postsynaptic specialization membrane	Kcnb1	IDA		Rat	PMID:14608003\|RGD:2303543
Cellular Component	GO:1990635	proximal dendrite	Kcnb1	IDA		Rat	PMID:24355600\|RGD:126908004
Cellular Component	GO:1990635	proximal dendrite	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNB1	IDA		Human	PMID:19074135
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNB1	IDA		Human	PMID:19223394
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Mouse	MGI:MGI:5508719\|PMID:22056818
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:17301173\|RGD:10047384
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:18167541\|RGD:10047360
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:19219384\|RGD:7243947
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:19690160\|RGD:10047295
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:8980147\|RGD:10047188
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnb1	IDA		Rat	PMID:9305895\|RGD:737625
Biological Process	GO:0001508	action potential	KCNB1	IDA		Human	PMID:19223394
Biological Process	GO:0001508	action potential	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179
Biological Process	GO:0071277	cellular response to calcium ion	Kcnb1	IDA		Rat	PMID:8978827\|RGD:150527856
Biological Process	GO:0071333	cellular response to glucose stimulus	Kcnb1	IDA		Mouse	MGI:MGI:3770494\|PMID:17767909
Biological Process	GO:0031669	cellular response to nutrient levels	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Biological Process	GO:0045163	clustering of voltage-gated potassium channels	Kcnb1	IDA		Rat	PMID:24355600\|RGD:126908004
Biological Process	GO:0090504	epiboly	kcnb1	IMP	ZFIN:ZDB-GENO-170504-3	Zfish	PMID:27729411
Biological Process	GO:0042593	glucose homeostasis	Kcnb1	IMP		Mouse	MGI:MGI:3770494\|PMID:17767909
Biological Process	GO:0007215	glutamate receptor signaling pathway	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Biological Process	GO:0046676	negative regulation of insulin secretion	Kcnb1	IMP		Mouse	MGI:MGI:3770494\|PMID:17767909
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Kcnb1	IDA		Rat	PMID:17301173\|RGD:10047384
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Kcnb1	IDA		Rat	PMID:18167541\|RGD:10047360
Biological Process	GO:0045956	positive regulation of calcium ion-dependent exocytosis	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179
Biological Process	GO:0033605	positive regulation of catecholamine secretion	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179
Biological Process	GO:1900454	positive regulation of long-term synaptic depression	Kcnb1	IMP		Mouse	MGI:MGI:5634878\|PMID:24494598
Biological Process	GO:0010701	positive regulation of norepinephrine secretion	Kcnb1	IDA		Rat	PMID:18167541\|RGD:10047360
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	KCNB1	IDA		Human	PMID:19074135
Biological Process	GO:0090314	positive regulation of protein targeting to membrane	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Biological Process	GO:0097623	potassium ion export across plasma membrane	Kcnb1	IMP		Rat	PMID:12127166\|RGD:1581351
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNB1	IDA		Human	PMID:19074135
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNB1	IDA		Human	PMID:19223394
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IMP		Mouse	MGI:MGI:5634878\|PMID:24494598
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Mouse	MGI:MGI:5508719\|PMID:22056818
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IMP		Mouse	MGI:MGI:3770494\|PMID:17767909
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:12954870\|RGD:10047250
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:19219384\|RGD:7243947
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:19690160\|RGD:10047295
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:20202934\|RGD:10047337
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnb1	IDA		Rat	PMID:8980147\|RGD:10047188
Biological Process	GO:0006813	potassium ion transport	Kcnb1	IDA		Rat	PMID:15046870\|RGD:8553483
Biological Process	GO:0006813	potassium ion transport	Kcnb1	IDA		Rat	PMID:8189205\|RGD:2303541
Biological Process	GO:0006813	potassium ion transport	Kcnb1	IDA		Rat	PMID:9305895\|RGD:737625
Biological Process	GO:0006813	potassium ion transport	Kcnb1	IMP		Rat	PMID:9545040\|RGD:2303542
Biological Process	GO:0072659	protein localization to plasma membrane	Kcnb1	IDA		Rat	PMID:9305895\|RGD:737625
Biological Process	GO:0098900	regulation of action potential	Kcnb1	IMP		Mouse	MGI:MGI:3770494\|PMID:17767909
Biological Process	GO:2000671	regulation of motor neuron apoptotic process	Kcnb1	IDA		Rat	PMID:19077057\|RGD:10047372
Biological Process	GO:0048678	response to axon injury	Kcnb1	IEP		Rat	PMID:24355600\|RGD:126908004
Biological Process	GO:1902065	response to L-glutamate	Kcnb1	IEP		Rat	PMID:24355600\|RGD:126908004
Biological Process	GO:0021591	ventricular system development	kcnb1	IMP	ZFIN:ZDB-GENO-170504-3	Zfish	PMID:27729411
Biological Process	GO:0006904	vesicle docking involved in exocytosis	Kcnb1	IDA		Rat	PMID:20484665\|RGD:10047179

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 08/02/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.