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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnb1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnb1
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNB1IDAHumanPMID:19074135
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKCNB1IDAHumanPMID:19223394
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IMPMouseMGI:MGI:5634878|PMID:24494598
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IMPMouseMGI:MGI:3770494|PMID:17767909
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDAMouseMGI:MGI:5508719|PMID:22056818
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:12954870|RGD:10047250
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:19077057|RGD:10047372
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:19219384|RGD:7243947
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:19690160|RGD:10047295
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:20202934|RGD:10047337
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:8189205|RGD:2303541
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:8980147|RGD:10047188
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IDARatPMID:9305895|RGD:737625
Molecular FunctionGO:0005251delayed rectifier potassium channel activityKcnb1IMPRatPMID:9545040|RGD:2303542
Molecular FunctionGO:0015271outward rectifier potassium channel activityKcnb1IMPRatPMID:12127166|RGD:1581351
Molecular FunctionGO:0005515protein bindingKCNB1IPIUniProtKB:Q96KK3HumanPMID:10484328
Molecular FunctionGO:0005515protein bindingKCNB1IPIUniProtKB:Q8TAE7HumanPMID:11852086
Molecular FunctionGO:0005515protein bindingKCNB1IPIUniProtKB:Q8TDN2HumanPMID:34535971
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:Q80ZD8MouseMGI:MGI:5508719|PMID:22056818
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P22460MousePMID:8576199
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:Q9JJV7RatPMID:12954870|RGD:10047250
Molecular FunctionGO:0005515protein bindingKcnb1IPIRGD:3728RatPMID:16478442|RGD:1581072
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P32851RatPMID:17301173|RGD:10047384
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P32851RatPMID:18167541|RGD:10047360
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P15383RatPMID:19219384|RGD:7243947
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P63161RatPMID:19219384|RGD:7243947
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P63045RatPMID:19690160|RGD:10047295
Molecular FunctionGO:0005515protein bindingKcnb1IPIUniProtKB:P32851RatPMID:20484665|RGD:10047179
Molecular FunctionGO:0046982protein heterodimerization activityKcnb1IDARatPMID:20202934|RGD:10047337
Molecular FunctionGO:0000149SNARE bindingKcnb1IPIUniProtKB:P32851RatPMID:19077057|RGD:10047372
Molecular FunctionGO:0000149SNARE bindingKcnb1IPIUniProtKB:P60881RatPMID:19077057|RGD:10047372
Molecular FunctionGO:0000149SNARE bindingKcnb1IPIUniProtKB:P63045RatPMID:19077057|RGD:10047372
Molecular FunctionGO:0044325transmembrane transporter bindingKCNB1IPIUniProtKB:Q8TDN1HumanPMID:19074135
Molecular FunctionGO:0044325transmembrane transporter bindingKcnb1IPIUniProtKB:Q63099RatPMID:20202934|RGD:10047337
Molecular FunctionGO:0005249voltage-gated potassium channel activityKcnb1IDARatPMID:15046870|RGD:8553483
Cellular ComponentGO:0016324apical plasma membraneKcnb1IMPRatPMID:8978827|RGD:150527856
Cellular ComponentGO:0030424axonKcnb1IDARatPMID:19014551|RGD:10047314
Cellular ComponentGO:0030424axonKcnb1IDARatPMID:22648171|RGD:10047382
Cellular ComponentGO:0009986cell surfaceKcnb1IDARatPMID:21943417|RGD:12910700
Cellular ComponentGO:0009986cell surfaceKcnb1IDARatPMID:8978827|RGD:150527856
Cellular ComponentGO:0098981cholinergic synapseKcnb1IDARatPMID:14608003|RGD:2303543
Cellular ComponentGO:0030425dendriteKcnb1IDAMouseMGI:MGI:5508719|PMID:22056818
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:12954870|RGD:10047250
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:19014551|RGD:10047314
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:19077057|RGD:10047372
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:20202934|RGD:10047337
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:22648171|RGD:10047382
Cellular ComponentGO:0030425dendriteKcnb1IDARatPMID:8463836|RGD:2303537
Cellular ComponentGO:0032590dendrite membraneKcnb1IDARatPMID:14608003|RGD:2303543
Cellular ComponentGO:0005783endoplasmic reticulumKcnb1IDARatPMID:21943417|RGD:12910700
Cellular ComponentGO:0016328lateral plasma membraneKcnb1IDARatPMID:8978827|RGD:150527856
Cellular ComponentGO:0016020membraneKcnb1IDARatPMID:8189205|RGD:2303541
Cellular ComponentGO:0043025neuronal cell bodyKcnb1IDARatPMID:8463836|RGD:2303537
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDAMouseMGI:MGI:5508719|PMID:22056818
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:12954870|RGD:10047250
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:14608003|RGD:2303543
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:19014551|RGD:10047314
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:19077057|RGD:10047372
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:20202934|RGD:10047337
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:22648171|RGD:10047382
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:24355600|RGD:126908004
Cellular ComponentGO:0032809neuronal cell body membraneKcnb1IDARatPMID:8978827|RGD:150527856
Cellular ComponentGO:0043204perikaryonKcnb1IDARatPMID:12954870|RGD:10047250
Cellular ComponentGO:0048471perinuclear region of cytoplasmKcnb1IDARatPMID:8978827|RGD:150527856
Cellular ComponentGO:0005886plasma membraneKCNB1IDAHumanPMID:19074135
Cellular ComponentGO:0005886plasma membraneKCNB1IDAHumanPMID:19223394
Cellular ComponentGO:0005886plasma membraneKcnb1IDAMouseMGI:MGI:3770494|PMID:17767909
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:17301173|RGD:10047384
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:18167541|RGD:10047360
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:19219384|RGD:7243947
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:19690160|RGD:10047295
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:20484665|RGD:10047179
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:8980147|RGD:10047188
Cellular ComponentGO:0005886plasma membraneKcnb1IDARatPMID:9305895|RGD:737625
Cellular ComponentGO:0045211postsynaptic membraneKcnb1IDARatPMID:14608003|RGD:2303543
Cellular ComponentGO:0099634postsynaptic specialization membraneKcnb1IDARatPMID:14608003|RGD:2303543
Cellular ComponentGO:1990635proximal dendriteKcnb1IDARatPMID:24355600|RGD:126908004
Cellular ComponentGO:1990635proximal dendriteKcnb1IDARatPMID:8978827|RGD:150527856
Cellular ComponentGO:0008076voltage-gated potassium channel complexKCNB1IDAHumanPMID:19074135
Cellular ComponentGO:0008076voltage-gated potassium channel complexKCNB1IDAHumanPMID:19223394
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDAMouseMGI:MGI:5508719|PMID:22056818
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:12954870|RGD:10047250
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:17301173|RGD:10047384
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:18167541|RGD:10047360
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:19077057|RGD:10047372
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:19219384|RGD:7243947
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:19690160|RGD:10047295
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:20202934|RGD:10047337
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:20484665|RGD:10047179
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:8980147|RGD:10047188
Cellular ComponentGO:0008076voltage-gated potassium channel complexKcnb1IDARatPMID:9305895|RGD:737625
Biological ProcessGO:0001508action potentialKCNB1IDAHumanPMID:19223394
Biological ProcessGO:0001508action potentialKcnb1IDARatPMID:20484665|RGD:10047179
Biological ProcessGO:0071277cellular response to calcium ionKcnb1IDARatPMID:8978827|RGD:150527856
Biological ProcessGO:0071333cellular response to glucose stimulusKcnb1IDAMouseMGI:MGI:3770494|PMID:17767909
Biological ProcessGO:0031669cellular response to nutrient levelsKcnb1IDARatPMID:19077057|RGD:10047372
Biological ProcessGO:0045163clustering of voltage-gated potassium channelsKcnb1IDARatPMID:24355600|RGD:126908004
Biological ProcessGO:0090504epibolykcnb1IMPZFIN:ZDB-GENO-170504-3ZfishPMID:27729411
Biological ProcessGO:0042593glucose homeostasisKcnb1IMPMouseMGI:MGI:3770494|PMID:17767909
Biological ProcessGO:0007215glutamate receptor signaling pathwayKcnb1IDARatPMID:19077057|RGD:10047372
Biological ProcessGO:0046676negative regulation of insulin secretionKcnb1IMPMouseMGI:MGI:3770494|PMID:17767909
Biological ProcessGO:0045956positive regulation of calcium ion-dependent exocytosisKcnb1IDARatPMID:17301173|RGD:10047384
Biological ProcessGO:0045956positive regulation of calcium ion-dependent exocytosisKcnb1IDARatPMID:18167541|RGD:10047360
Biological ProcessGO:0045956positive regulation of calcium ion-dependent exocytosisKcnb1IDARatPMID:20484665|RGD:10047179
Biological ProcessGO:0033605positive regulation of catecholamine secretionKcnb1IDARatPMID:20484665|RGD:10047179
Biological ProcessGO:1900454positive regulation of long-term synaptic depressionKcnb1IMPMouseMGI:MGI:5634878|PMID:24494598
Biological ProcessGO:0010701positive regulation of norepinephrine secretionKcnb1IDARatPMID:18167541|RGD:10047360
Biological ProcessGO:0090314positive regulation of protein targeting to membraneKCNB1IDAHumanPMID:19074135
Biological ProcessGO:0090314positive regulation of protein targeting to membraneKcnb1IDARatPMID:12954870|RGD:10047250
Biological ProcessGO:0097623potassium ion export across plasma membraneKcnb1IMPRatPMID:12127166|RGD:1581351
Biological ProcessGO:0071805potassium ion transmembrane transportKCNB1IDAHumanPMID:19074135
Biological ProcessGO:0071805potassium ion transmembrane transportKCNB1IDAHumanPMID:19223394
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IMPMouseMGI:MGI:5634878|PMID:24494598
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDAMouseMGI:MGI:5508719|PMID:22056818
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IMPMouseMGI:MGI:3770494|PMID:17767909
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:12954870|RGD:10047250
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:19077057|RGD:10047372
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:19219384|RGD:7243947
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:19690160|RGD:10047295
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:20202934|RGD:10047337
Biological ProcessGO:0071805potassium ion transmembrane transportKcnb1IDARatPMID:8980147|RGD:10047188
Biological ProcessGO:0006813potassium ion transportKcnb1IDARatPMID:15046870|RGD:8553483
Biological ProcessGO:0006813potassium ion transportKcnb1IDARatPMID:8189205|RGD:2303541
Biological ProcessGO:0006813potassium ion transportKcnb1IDARatPMID:9305895|RGD:737625
Biological ProcessGO:0006813potassium ion transportKcnb1IMPRatPMID:9545040|RGD:2303542
Biological ProcessGO:0072659protein localization to plasma membraneKcnb1IDARatPMID:9305895|RGD:737625
Biological ProcessGO:0098900regulation of action potentialKcnb1IMPMouseMGI:MGI:3770494|PMID:17767909
Biological ProcessGO:2000671regulation of motor neuron apoptotic processKcnb1IDARatPMID:19077057|RGD:10047372
Biological ProcessGO:0048678response to axon injuryKcnb1IEPRatPMID:24355600|RGD:126908004
Biological ProcessGO:1902065response to L-glutamateKcnb1IEPRatPMID:24355600|RGD:126908004
Biological ProcessGO:0021591ventricular system developmentkcnb1IMPZFIN:ZDB-GENO-170504-3ZfishPMID:27729411
Biological ProcessGO:0006904vesicle docking involved in exocytosisKcnb1IDARatPMID:20484665|RGD:10047179

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory