Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnc1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNC1
- Mouse genes Kcnc1
- Rat genes Kcnc1
- Zfish genes kcnc1a,kcnc1b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnc1	IDA		Rat	PMID:12954870\|RGD:10047250
Molecular Function	GO:0019894	kinesin binding	Kcnc1	IDA		Mouse	PMID:21106837
Molecular Function	GO:0005515	protein binding	KCNC1	IPI	UniProtKB:A5PKU2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNC1	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNC1	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	UniProtKB:Q14B80	Mouse	MGI:MGI:5619495\|PMID:10531438
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	RGD:620157	Rat	PMID:12805291\|RGD:9685703
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	RGD:628829	Rat	PMID:12805291\|RGD:9685703
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	UniProtKB:Q9JJV7	Rat	PMID:12954870\|RGD:10047250
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	RGD:2956	Rat	PMID:14679187\|RGD:7243967
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	RGD:621383	Rat	PMID:14679187\|RGD:7243967
Molecular Function	GO:0005515	protein binding	Kcnc1	IPI	RGD:1589169	Rat	PMID:21943417\|RGD:12910700
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnc1	IPI	UniProtKB:Q14B80	Mouse	MGI:MGI:5619747\|PMID:12000114
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnc1	IPI	UniProtKB:P22462	Rat	PMID:10482766\|RGD:9685780
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnc1	IDA		Rat	PMID:10482766\|RGD:9685780
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnc1	IMP		Rat	PMID:10482766\|RGD:9685780
Cellular Component	GO:0030673	axolemma	Kcnc1	IDA		Mouse	PMID:18682278
Cellular Component	GO:0044305	calyx of Held	Kcnc1	IDA		Rat	PMID:14614103\|RGD:13702408
Cellular Component	GO:0009986	cell surface	Kcnc1	IDA		Rat	PMID:18256021\|RGD:9685704
Cellular Component	GO:0030425	dendrite	Kcnc1	IDA		Rat	PMID:11494252\|RGD:9685713
Cellular Component	GO:0032590	dendrite membrane	Kcnc1	IDA		Mouse	PMID:18682278
Cellular Component	GO:0016020	membrane	Kcnc1	IDA		Rat	PMID:12805291\|RGD:9685703
Cellular Component	GO:0032589	neuron projection membrane	Kcnc1	IDA		Rat	PMID:18256021\|RGD:9685704
Cellular Component	GO:0043025	neuronal cell body	Kcnc1	IDA		Rat	PMID:11494252\|RGD:9685713
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc1	IDA		Mouse	PMID:18682278
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc1	IDA		Rat	PMID:12954870\|RGD:10047250
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc1	IDA		Rat	PMID:18256021\|RGD:9685704
Cellular Component	GO:0045211	postsynaptic membrane	Kcnc1	IDA		Rat	PMID:14614103\|RGD:13702408
Cellular Component	GO:0042734	presynaptic membrane	Kcnc1	IDA		Rat	PMID:14614103\|RGD:13702408
Cellular Component	GO:0042734	presynaptic membrane	Kcnc1	IDA		Rat	PMID:20857303\|RGD:13702181
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNC1	IDA		Human	PMID:23734863
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnc1	IDA		Rat	PMID:12954870\|RGD:10047250
Biological Process	GO:0007420	brain development	Kcnc1	IEP		Rat	PMID:1432046\|RGD:9685709
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Kcnc1	IEP		Rat	PMID:11543764\|RGD:9685702
Biological Process	GO:0021549	cerebellum development	Kcnc1	IEP		Rat	PMID:9526005\|RGD:9685724
Biological Process	GO:0022038	corpus callosum development	Kcnc1	IEP		Rat	PMID:22473424\|RGD:10411906
Biological Process	GO:0021759	globus pallidus development	Kcnc1	IEP		Rat	PMID:10482766\|RGD:9685780
Biological Process	GO:0021554	optic nerve development	Kcnc1	IEP		Rat	PMID:22473424\|RGD:10411906
Biological Process	GO:0034767	positive regulation of monoatomic ion transmembrane transport	Kcnc1	IDA		Rat	PMID:7472324\|RGD:9685701
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	Kcnc1	IDA		Rat	PMID:8436968\|RGD:9685720
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	Kcnc1	IDA		Rat	PMID:21943417\|RGD:12910700
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnc1	IDA		Rat	PMID:12954870\|RGD:10047250
Biological Process	GO:0051262	protein tetramerization	KCNC1	IDA		Human	PMID:23734863
Biological Process	GO:0034765	regulation of monoatomic ion transmembrane transport	Kcnc1	IMP		Rat	PMID:21541302\|RGD:9686071
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	Kcnc1	IDA		Rat	PMID:14679187\|RGD:7243967
Biological Process	GO:0014075	response to amine	Kcnc1	IEP		Rat	PMID:18775767\|RGD:9685735
Biological Process	GO:0010996	response to auditory stimulus	Kcnc1	IEP		Rat	PMID:20219640\|RGD:9685726
Biological Process	GO:0071774	response to fibroblast growth factor	Kcnc1	IEP		Rat	PMID:9526005\|RGD:9685724
Biological Process	GO:0009642	response to light intensity	Kcnc1	IEP		Rat	PMID:18708127\|RGD:9685740
Biological Process	GO:1990089	response to nerve growth factor	Kcnc1	IEP		Rat	PMID:18775767\|RGD:9685735
Biological Process	GO:1990089	response to nerve growth factor	Kcnc1	IEP		Rat	PMID:9526005\|RGD:9685724
Biological Process	GO:0035864	response to potassium ion	Kcnc1	IEP		Rat	PMID:9526005\|RGD:9685724
Biological Process	GO:0009636	response to toxic substance	Kcnc1	IEP		Rat	PMID:18775767\|RGD:9685735

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 07/05/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.