Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNC2
  • Mouse genes Kcnc2
  • Rat genes Kcnc2
  • Zfish genes kcnc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Molecular Function	GO:0005515	protein binding	Kcnc2	IPI	UniProtKB:P15388	Mouse	MGI:MGI:5619495|PMID:10531438
Molecular Function	GO:0005515	protein binding	Kcnc2	IPI	RGD:2955	Rat	PMID:12805291|RGD:9685703
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnc2	IPI	UniProtKB:P15388	Mouse	MGI:MGI:5619747|PMID:12000114
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnc2	IPI	UniProtKB:P25122	Rat	PMID:10482766|RGD:9685780
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Molecular Function	GO:0099508	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Kcnc2	IMP		Rat	PMID:10482766|RGD:9685780
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Cellular Component	GO:0016324	apical plasma membrane	Kcnc2	IDA		Rat	PMID:9307441|RGD:9686055
Cellular Component	GO:0030673	axolemma	Kcnc2	IDA		Rat	PMID:15488478|RGD:9685742
Cellular Component	GO:0030424	axon	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Cellular Component	GO:0016323	basolateral plasma membrane	Kcnc2	IDA		Rat	PMID:9307441|RGD:9686055
Cellular Component	GO:0030425	dendrite	Kcnc2	IDA		Mouse	MGI:MGI:5619495|PMID:10531438
Cellular Component	GO:0030425	dendrite	Kcnc2	IDA		Mouse	MGI:MGI:5619747|PMID:12000114
Cellular Component	GO:0030425	dendrite	Kcnc2	IDA		Rat	PMID:16413129|RGD:9685738
Cellular Component	GO:0098982	GABA-ergic synapse	Kcnc2	IDA		Rat	PMID:10531438|RGD:155230790
Cellular Component	GO:0016020	membrane	Kcnc2	IDA		Mouse	MGI:MGI:5619747|PMID:12000114
Cellular Component	GO:0043025	neuronal cell body	Kcnc2	IDA		Rat	PMID:16413129|RGD:9685738
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc2	IDA		Mouse	MGI:MGI:5619495|PMID:10531438
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Cellular Component	GO:0043204	perikaryon	Kcnc2	IDA		Mouse	MGI:MGI:5619747|PMID:12000114
Cellular Component	GO:0043204	perikaryon	Kcnc2	IDA		Mouse	MGI:MGI:5619495|PMID:10531438
Cellular Component	GO:0043204	perikaryon	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Cellular Component	GO:0005886	plasma membrane	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Cellular Component	GO:0005886	plasma membrane	Kcnc2	IDA		Rat	PMID:15488478|RGD:9685742
Cellular Component	GO:0045211	postsynaptic membrane	Kcnc2	IDA		Mouse	MGI:MGI:5619495|PMID:10531438
Cellular Component	GO:0042734	presynaptic membrane	Kcnc2	IDA		Mouse	MGI:MGI:5619495|PMID:10531438
Cellular Component	GO:0042734	presynaptic membrane	Kcnc2	IDA		Rat	PMID:10531438|RGD:155230790
Cellular Component	GO:0045202	synapse	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Cellular Component	GO:0043195	terminal bouton	Kcnc2	IDA		Rat	PMID:15488478|RGD:9685742
Cellular Component	GO:0031982	vesicle	Kcnc2	IDA		Rat	PMID:15488478|RGD:9685742
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Biological Process	GO:0001508	action potential	Kcnc2	IMP	MGI:MGI:2387957	Mouse	PMID:17761775
Biological Process	GO:0071242	cellular response to ammonium ion	Kcnc2	IEP		Rat	PMID:10482766|RGD:9685780
Biological Process	GO:0071732	cellular response to nitric oxide	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Biological Process	GO:0097237	cellular response to toxic substance	Kcnc2	IMP		Rat	PMID:16177043|RGD:9686061
Biological Process	GO:0097237	cellular response to toxic substance	Kcnc2	IEP		Rat	PMID:17855760|RGD:9685744
Biological Process	GO:0021759	globus pallidus development	Kcnc2	IEP		Rat	PMID:10482766|RGD:9685780
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Kcnc2	IDA		Rat	PMID:17855760|RGD:9685744
Biological Process	GO:0038060	nitric oxide-cGMP-mediated signaling pathway	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Biological Process	GO:0021554	optic nerve development	Kcnc2	IEP		Rat	PMID:22473424|RGD:10411906
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	Kcnc2	IDA		Rat	PMID:1879548|RGD:729260
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	Kcnc2	IDA		Rat	PMID:21943417|RGD:12910700
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnc2	IDA		Rat	PMID:11281123|RGD:10047322
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnc2	IDA		Rat	PMID:7643197|RGD:9686052
Biological Process	GO:0051291	protein heterooligomerization	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Biological Process	GO:0051260	protein homooligomerization	Kcnc2	IDA		Rat	PMID:10482766|RGD:9685780
Biological Process	GO:0014075	response to amine	Kcnc2	IEP		Rat	PMID:18775767|RGD:9685735
Biological Process	GO:0045471	response to ethanol	Kcnc2	IEP		Rat	PMID:21234782|RGD:9685743
Biological Process	GO:0009642	response to light intensity	Kcnc2	IEP		Rat	PMID:18708127|RGD:9685740
Biological Process	GO:0032026	response to magnesium ion	Kcnc2	IEP		Rat	PMID:18775767|RGD:9685735
Biological Process	GO:1990089	response to nerve growth factor	Kcnc2	IEP		Rat	PMID:18775767|RGD:9685735
Biological Process	GO:0014070	response to organic cyclic compound	Kcnc2	IEP		Rat	PMID:7643197|RGD:9686052
Biological Process	GO:0009636	response to toxic substance	Kcnc2	IEP		Rat	PMID:18775767|RGD:9685735

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern