Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNC3
  • Mouse genes Kcnc3
  • Rat genes Kcnc3
  • Zfish genes kcnc3a,kcnc3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNC3	IMP		Human	PMID:19953606
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNC3	IMP		Human	PMID:21479265
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNC3	IMP		Human	PMID:23734863
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNC3	IMP		Human	PMID:25756792
Molecular Function	GO:0005249	voltage-gated potassium channel activity	kcnc3a	IDA		Zfish	PMID:20712895
Cellular Component	GO:0030673	axolemma	Kcnc3	IDA		Mouse	PMID:18682278
Cellular Component	GO:0043679	axon terminus	Kcnc3	IDA		Mouse	PMID:15610163
Cellular Component	GO:0032590	dendrite membrane	Kcnc3	IDA		Mouse	PMID:18682278
Cellular Component	GO:0098978	glutamatergic synapse	Kcnc3	IDA		Rat	PMID:20857303|RGD:13702181
Cellular Component	GO:0031594	neuromuscular junction	Kcnc3	IDA		Mouse	PMID:15610163
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnc3	IDA		Mouse	PMID:18682278
Cellular Component	GO:0005886	plasma membrane	KCNC3	IDA		Human	PMID:23734863
Cellular Component	GO:0005886	plasma membrane	KCNC3	IDA		Human	PMID:25152487
Cellular Component	GO:0005886	plasma membrane	KCNC3	IDA		Human	PMID:25756792
Cellular Component	GO:0045211	postsynaptic membrane	Kcnc3	IDA		Rat	PMID:20857303|RGD:13702181
Cellular Component	GO:0042734	presynaptic membrane	Kcnc3	IDA		Rat	PMID:20857303|RGD:13702181
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNC3	IDA		Human	PMID:23734863
Biological Process	GO:0022038	corpus callosum development	Kcnc3	IEP		Rat	PMID:22473424|RGD:10411906
Biological Process	GO:0008045	motor neuron axon guidance	kcnc3a	IMP		Zfish	PMID:22736459
Biological Process	GO:0048666	neuron development	kcnc3a	IMP		Zfish	PMID:22736459
Biological Process	GO:0021554	optic nerve development	Kcnc3	IEP		Rat	PMID:22473424|RGD:10411906
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNC3	IMP		Human	PMID:19953606
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNC3	IMP		Human	PMID:21479265
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNC3	IMP		Human	PMID:23734863
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNC3	IMP		Human	PMID:25756792
Biological Process	GO:0051262	protein tetramerization	KCNC3	IDA		Human	PMID:23734863
Biological Process	GO:0046928	regulation of neurotransmitter secretion	Kcnc3	IMP		Mouse	PMID:15610163

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern