Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcnd2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCND2
- Mouse genes Kcnd2
- Rat genes Kcnd2
- Zfish genes kcnd2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	KCND2	IMP		Human	PMID:15454437
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	Kcnd2	IMP		Mouse	MGI:MGI:3765088\|PMID:18045912
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	Kcnd2	IMP		Rat	PMID:16123112\|RGD:1581377
Molecular Function	GO:0005250	A-type (transient outward) potassium channel activity	Kcnd2	IDA		Rat	PMID:9093524\|RGD:10047150
Molecular Function	GO:0005216	monoatomic ion channel activity	Kcnd2	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005267	potassium channel activity	Kcnd2	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005267	potassium channel activity	Kcnd2	IDA		Rat	PMID:12403671\|RGD:633152
Molecular Function	GO:0005515	protein binding	KCND2	IPI	UniProtKB:Q9NS61	Human	PMID:11287421
Molecular Function	GO:0005515	protein binding	KCND2	IPI	UniProtKB:Q9NS61	Human	PMID:14623880
Molecular Function	GO:0005515	protein binding	KCND2	IPI	UniProtKB:Q9NS61	Human	PMID:14980201
Molecular Function	GO:0005515	protein binding	KCND2	IPI	UniProtKB:Q9NS61-3	Human	PMID:15358149
Molecular Function	GO:0005515	protein binding	KCND2	IPI	UniProtKB:Q9NZI2	Human	PMID:15358149
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	UniProtKB:Q99PW8	Mouse	MGI:MGI:3616289\|PMID:16257958
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	PR:Q9D808	Mouse	PMID:18603586
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	PR:P63143	Mouse	PMID:15662035
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:708539	Rat	PMID:11805342\|RGD:1299518
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:68402	Rat	PMID:12575952\|RGD:5687190
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:70886	Rat	PMID:14980206\|RGD:1581450
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:70887	Rat	PMID:15356203\|RGD:1580506
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:1306427	Rat	PMID:16123112\|RGD:1581377
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:70888	Rat	PMID:16123112\|RGD:1581377
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:3631	Rat	PMID:18565539\|RGD:6484256
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:70886	Rat	PMID:20849929\|RGD:7205509
Molecular Function	GO:0005515	protein binding	Kcnd2	IPI	RGD:70888	Rat	PMID:21147063\|RGD:7207197
Molecular Function	GO:0044877	protein-containing complex binding	Kcnd2	IDA		Rat	PMID:14980206\|RGD:1581450
Molecular Function	GO:0044877	protein-containing complex binding	Kcnd2	IDA		Rat	PMID:16123112\|RGD:1581377
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Kcnd2	IDA		Mouse	PMID:17582333
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Kcnd2	IMP		Mouse	PMID:17582333
Molecular Function	GO:1905030	voltage-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Kcnd2	IMP		Rat	PMID:17582333\|RGD:12050096
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCND2	IDA		Human	PMID:24811166
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd2	IDA		Rat	PMID:10325948\|RGD:628469
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd2	IDA		Rat	PMID:12967630\|RGD:7207200
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd2	IDA		Rat	PMID:14980206\|RGD:1581450
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd2	IMP		Rat	PMID:16123112\|RGD:1581377
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcnd2	IDA		Rat	PMID:1722463\|RGD:628471
Cellular Component	GO:0005901	caveola	Kcnd2	IDA		Rat	PMID:20224290\|RGD:6902941
Cellular Component	GO:0030425	dendrite	Kcnd2	IDA		Mouse	MGI:MGI:5613484\|PMID:11040264
Cellular Component	GO:0030425	dendrite	Kcnd2	IDA		Rat	PMID:15356203\|RGD:1580506
Cellular Component	GO:0030425	dendrite	Kcnd2	IDA		Rat	PMID:15736227\|RGD:1581384
Cellular Component	GO:0043197	dendritic spine	Kcnd2	IDA		Mouse	PMID:21943606
Cellular Component	GO:0043197	dendritic spine	Kcnd2	IDA		Rat	PMID:16141270\|RGD:1581430
Cellular Component	GO:0043197	dendritic spine	Kcnd2	IDA		Rat	PMID:9070739\|RGD:10047325
Cellular Component	GO:0098982	GABA-ergic synapse	Kcnd2	IDA		Mouse	PMID:17122053
Cellular Component	GO:0098978	glutamatergic synapse	Kcnd2	IMP		Mouse	PMID:17582333
Cellular Component	GO:0098978	glutamatergic synapse	Kcnd2	IDA		Mouse	PMID:17582333
Cellular Component	GO:0098978	glutamatergic synapse	Kcnd2	IDA		Mouse	PMID:17122053
Cellular Component	GO:0098978	glutamatergic synapse	Kcnd2	IDA		Rat	PMID:17582333\|RGD:12050096
Cellular Component	GO:0016020	membrane	Kcnd2	IDA		Mouse	PMID:18603586
Cellular Component	GO:0043005	neuron projection	Kcnd2	IDA		Rat	PMID:17635915\|RGD:2306826
Cellular Component	GO:0043025	neuronal cell body	Kcnd2	IDA		Mouse	MGI:MGI:5613484\|PMID:11040264
Cellular Component	GO:0043025	neuronal cell body	Kcnd2	IDA		Rat	PMID:15736227\|RGD:1581384
Cellular Component	GO:0043025	neuronal cell body	Kcnd2	IDA		Rat	PMID:20849929\|RGD:7205509
Cellular Component	GO:0032809	neuronal cell body membrane	Kcnd2	IDA		Rat	PMID:9070739\|RGD:10047325
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	Kcnd2	IDA		Rat	PMID:12967630\|RGD:7207200
Cellular Component	GO:0005886	plasma membrane	KCND2	IMP		Human	PMID:15454437
Cellular Component	GO:0005886	plasma membrane	KCND2	IDA		Human	PMID:24811166
Cellular Component	GO:0005886	plasma membrane	Kcnd2	IDA		Rat	PMID:10330244\|RGD:628470
Cellular Component	GO:0005886	plasma membrane	Kcnd2	IDA		Rat	PMID:12967630\|RGD:7207200
Cellular Component	GO:0005886	plasma membrane	Kcnd2	IDA		Rat	PMID:15736227\|RGD:1581384
Cellular Component	GO:0005886	plasma membrane	Kcnd2	IMP		Rat	PMID:1722463\|RGD:628471
Cellular Component	GO:0044853	plasma membrane raft	Kcnd2	IDA		Rat	PMID:24793047\|RGD:10047216
Cellular Component	GO:0014069	postsynaptic density	Kcnd2	IDA		Rat	PMID:17635915\|RGD:2306826
Cellular Component	GO:0045211	postsynaptic membrane	Kcnd2	IDA		Mouse	PMID:17122053
Cellular Component	GO:0045211	postsynaptic membrane	Kcnd2	IDA		Rat	PMID:17582333\|RGD:12050096
Cellular Component	GO:0045211	postsynaptic membrane	Kcnd2	IDA		Rat	PMID:9070739\|RGD:10047325
Cellular Component	GO:0099634	postsynaptic specialization membrane	Kcnd2	IDA		Mouse	PMID:17122053
Cellular Component	GO:0034705	potassium channel complex	Kcnd2	IDA		Rat	PMID:14980206\|RGD:1581450
Cellular Component	GO:0042383	sarcolemma	Kcnd2	IDA		Rat	PMID:10860776\|RGD:10047321
Cellular Component	GO:0030315	T-tubule	Kcnd2	IDA		Rat	PMID:10860776\|RGD:10047321
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCND2	IDA		Human	PMID:15454437
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCND2	IDA		Human	PMID:24811166
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd2	IDA		Mouse	MGI:MGI:5616313\|PMID:19713751
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd2	IDA		Rat	PMID:15356203\|RGD:1580506
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd2	IDA		Rat	PMID:16123112\|RGD:1581377
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnd2	IDA		Rat	PMID:20224290\|RGD:6902941
Biological Process	GO:0001508	action potential	Kcnd2	IMP		Rat	PMID:16141270\|RGD:1581430
Biological Process	GO:0086001	cardiac muscle cell action potential	Kcnd2	IMP		Rat	PMID:9058605\|RGD:10047324
Biological Process	GO:0071456	cellular response to hypoxia	Kcnd2	IDA		Rat	PMID:25352783\|RGD:10047379
Biological Process	GO:0071260	cellular response to mechanical stimulus	Kcnd2	IEP		Rat	PMID:17293496\|RGD:7247436
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Kcnd2	IEP		Rat	PMID:17293496\|RGD:7247436
Biological Process	GO:0045475	locomotor rhythm	Kcnd2	IMP		Mouse	MGI:MGI:5432624\|PMID:22815518
Biological Process	GO:0019228	neuronal action potential	Kcnd2	IMP		Mouse	MGI:MGI:5432624\|PMID:22815518
Biological Process	GO:0019228	neuronal action potential	Kcnd2	IMP		Mouse	PMID:20573902
Biological Process	GO:0071805	potassium ion transmembrane transport	KCND2	IDA		Human	PMID:15454437
Biological Process	GO:0071805	potassium ion transmembrane transport	KCND2	IDA		Human	PMID:24811166
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnd2	IMP		Mouse	MGI:MGI:3765088\|PMID:18045912
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcnd2	IDA		Rat	PMID:1722463\|RGD:628471
Biological Process	GO:0019233	sensory perception of pain	Kcnd2	IMP		Mouse	MGI:MGI:3765088\|PMID:18045912

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.