Comparative GO Graph (mouse, human, rat)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Kcne1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes KCNE1
- Mouse genes Kcne1
- Rat genes Kcne1
- Zfish genes
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcne1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:10400998
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:11299204
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:12522251
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:19646991
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:8900283
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:9354802
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:24269949
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	Kcne1	IMP		Rat	PMID:11810210\|RGD:729219
Molecular Function	GO:0015459	potassium channel regulator activity	KCNE1	IDA		Human	PMID:10400998
Molecular Function	GO:0015459	potassium channel regulator activity	KCNE1	IDA		Human	PMID:11220365
Molecular Function	GO:0015459	potassium channel regulator activity	KCNE1	IDA		Human	PMID:12522251
Molecular Function	GO:0015459	potassium channel regulator activity	KCNE1	IDA		Human	PMID:19219384
Molecular Function	GO:0015459	potassium channel regulator activity	KCNE1	IDA		Human	PMID:8900283
Molecular Function	GO:0015459	potassium channel regulator activity	Kcne1	IDA		Mouse	MGI:MGI:83868\|PMID:8900282
Molecular Function	GO:0015459	potassium channel regulator activity	Kcne1	IDA		Rat	PMID:19219384\|RGD:7243947
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:P51787	Human	PMID:11101505
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:A6HIS0	Human	PMID:11697903
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:P51787	Human	PMID:19521339
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:P51787	Human	PMID:20196769
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:P51787	Human	PMID:20533308
Molecular Function	GO:0005515	protein binding	KCNE1	IPI	UniProtKB:P51787	Human	PMID:25037568
Molecular Function	GO:0005515	protein binding	Kcne1	IPI	RGD:2955	Rat	PMID:14679187\|RGD:7243967
Molecular Function	GO:0005515	protein binding	Kcne1	IPI	RGD:621503	Rat	PMID:15389592\|RGD:1580497
Molecular Function	GO:0005515	protein binding	Kcne1	IPI	RGD:2952	Rat	PMID:21943416\|RGD:7242916
Molecular Function	GO:0005515	protein binding	Kcne1	IPI	RGD:1589169	Rat	PMID:21943417\|RGD:12910700
Molecular Function	GO:0044877	protein-containing complex binding	Kcne1	IPI	RGD:1353354	Rat	PMID:20962273\|RGD:7242917
Molecular Function	GO:0031433	telethonin binding	KCNE1	IPI	UniProtKB:O15273	Human	PMID:11697903
Molecular Function	GO:0044325	transmembrane transporter binding	Kcne1	IPI	UniProtKB:P15387	Rat	PMID:19219384\|RGD:7243947
Molecular Function	GO:0005249	voltage-gated potassium channel activity	KCNE1	IDA		Human	PMID:17289006
Molecular Function	GO:0005249	voltage-gated potassium channel activity	Kcne1	IMP		Rat	PMID:11810210\|RGD:729219
Molecular Function	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	KCNE1	IDA		Human	PMID:10400998
Molecular Function	GO:1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	KCNE1	IMP		Human	PMID:9354802
Cellular Component	GO:0016324	apical plasma membrane	Kcne1	IDA		Mouse	PMID:11223304
Cellular Component	GO:0016324	apical plasma membrane	Kcne1	IDA		Rat	PMID:2154581\|RGD:7243875
Cellular Component	GO:0009986	cell surface	KCNE1	IDA		Human	PMID:10400998
Cellular Component	GO:0009986	cell surface	Kcne1	IDA		Mouse	PMID:16901941
Cellular Component	GO:0005783	endoplasmic reticulum	Kcne1	IDA		Rat	PMID:21943416\|RGD:7242916
Cellular Component	GO:0005794	Golgi apparatus	Kcne1	IDA		Rat	PMID:21943416\|RGD:7242916
Cellular Component	GO:0005764	lysosome	KCNE1	HDA		Human	PMID:16780588
Cellular Component	GO:0005886	plasma membrane	KCNE1	HDA		Human	PMID:16780588
Cellular Component	GO:0005886	plasma membrane	KCNE1	IDA		Human	PMID:19219384
Cellular Component	GO:0005886	plasma membrane	Kcne1	IDA		Rat	PMID:19219384\|RGD:7243947
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNE1	IDA		Human	PMID:17289006
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNE1	IDA		Human	PMID:19646991
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcne1	IDA		Rat	PMID:15389592\|RGD:1580497
Cellular Component	GO:0030018	Z disc	Kcne1	IDA		Rat	PMID:11697903\|RGD:8554365
Biological Process	GO:0086002	cardiac muscle cell action potential involved in contraction	KCNE1	IMP		Human	PMID:10400998
Biological Process	GO:0071468	cellular response to acidic pH	Kcne1	IDA		Rat	PMID:8458414\|RGD:7243874
Biological Process	GO:0071320	cellular response to cAMP	KCNE1	IDA		Human	PMID:11299204
Biological Process	GO:0071482	cellular response to light stimulus	Kcne1	IEP		Rat	PMID:24202060\|RGD:12910722
Biological Process	GO:0002070	epithelial cell maturation	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:11223304
Biological Process	GO:0060047	heart contraction	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:14561835
Biological Process	GO:0008584	male gonad development	Kcne1	IEP		Rat	PMID:15389592\|RGD:1580497
Biological Process	GO:0086009	membrane repolarization	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:0086011	membrane repolarization during action potential	KCNE1	IDA		Human	PMID:11299204
Biological Process	GO:0086011	membrane repolarization during action potential	KCNE1	IDA		Human	PMID:19646991
Biological Process	GO:0086011	membrane repolarization during action potential	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:0086013	membrane repolarization during cardiac muscle cell action potential	KCNE1	IMP		Human	PMID:10400998
Biological Process	GO:0086013	membrane repolarization during cardiac muscle cell action potential	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:0098915	membrane repolarization during ventricular cardiac muscle cell action potential	KCNE1	IMP		Human	PMID:9354802
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:19219384
Biological Process	GO:1902260	negative regulation of delayed rectifier potassium channel activity	Kcne1	IDA		Rat	PMID:19219384\|RGD:7243947
Biological Process	GO:0090315	negative regulation of protein targeting to membrane	Kcne1	IDA		Rat	PMID:21943416\|RGD:7242916
Biological Process	GO:1903817	negative regulation of voltage-gated potassium channel activity	Kcne1	IDA		Rat	PMID:14679187\|RGD:7243967
Biological Process	GO:1903817	negative regulation of voltage-gated potassium channel activity	Kcne1	IDA		Rat	PMID:21943416\|RGD:7242916
Biological Process	GO:1903817	negative regulation of voltage-gated potassium channel activity	Kcne1	IDA		Rat	PMID:21943417\|RGD:12910700
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	Kcne1	IDA		Rat	PMID:7957868\|RGD:7243866
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	Kcne1	IDA		Rat	PMID:14679187\|RGD:7243967
Biological Process	GO:1903818	positive regulation of voltage-gated potassium channel activity	Kcne1	IMP		Rat	PMID:7568179\|RGD:12910723
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCNE1	IDA		Human	PMID:10400998
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCNE1	IDA		Human	PMID:17289006
Biological Process	GO:0097623	potassium ion export across plasma membrane	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNE1	IDA		Human	PMID:11299204
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNE1	IDA		Human	PMID:8900283
Biological Process	GO:0071805	potassium ion transmembrane transport	KCNE1	IDA		Human	PMID:9354802
Biological Process	GO:0071805	potassium ion transmembrane transport	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:11889581
Biological Process	GO:1902259	regulation of delayed rectifier potassium channel activity	KCNE1	IDA		Human	PMID:10400998
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	KCNE1	IMP		Human	PMID:10400998
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:14561835
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	KCNE1	IDA		Human	PMID:10400998
Biological Process	GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	KCNE1	IMP		Human	PMID:9354802
Biological Process	GO:0033363	secretory granule organization	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:11889581
Biological Process	GO:0086005	ventricular cardiac muscle cell action potential	KCNE1	IMP		Human	PMID:9354802
Biological Process	GO:0021750	vestibular nucleus development	Kcne1	IMP	MGI:MGI:1857442	Mouse	PMID:11223304

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.