Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNIP3
  • Mouse genes Kcnip3
  • Rat genes Kcnip3
  • Zfish genes kcnip3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnip3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005509	calcium ion binding	Kcnip3	IMP		Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0048306	calcium-dependent protein binding	Kcnip3	IPI	UniProtKB:Q9QXT8	Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0048306	calcium-dependent protein binding	Kcnip3	IPI	PR:Q61124	Mouse	PMID:17189291
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	Kcnip3	IMP		Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0003677	DNA binding	Kcnip3	IDA		Mouse	PMID:11792319
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	KCNIP3	IDA		Human	PMID:10078534
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Kcnip3	IMP		Mouse	MGI:MGI:2158115|PMID:11792319
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Kcnip3	IDA		Mouse	MGI:MGI:2158115|PMID:11792319
Molecular Function	GO:0043167	ion binding	Kcnip3	EXP		Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0000287	magnesium ion binding	Kcnip3	IMP		Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0140677	molecular function activator activity	Kcnip3	EXP		Mouse	MGI:MGI:5882899|PMID:15746104
Molecular Function	GO:0015459	potassium channel regulator activity	Kcnip3	IMP		Mouse	MGI:MGI:4837570|PMID:20943905
Molecular Function	GO:0015459	potassium channel regulator activity	Kcnip3	IDA		Rat	PMID:12829703|RGD:1299235
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q8N6Q3	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q13286	Human	PMID:17189291
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P08069	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q17RA0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q7Z434	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q8N6Q3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:A0A1U9X8X8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:O60844	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P08069	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P08294	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P40189	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q12797-6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q7Z5G4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q7Z7F0-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q86TD4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q8N6Q3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q9BXJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:O14843	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P08865	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:P57682	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q8IUR5-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q8WZ73-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KCNIP3	IPI	UniProtKB:Q9BXU0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Kcnip3	IPI	PR:Q61124	Mouse	PMID:17189291
Molecular Function	GO:0005515	protein binding	Kcnip3	IPI	RGD:68393	Rat	PMID:16123112|RGD:1581377
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	KCNIP3	IDA		Human	PMID:10078534
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Kcnip3	IDA		Mouse	MGI:MGI:2158115|PMID:11792319
Molecular Function	GO:0043565	sequence-specific DNA binding	Kcnip3	IDA		Rat	PMID:18191896|RGD:7207199
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnip3	IPI	RGD:68393	Rat	PMID:21147063|RGD:7207197
Molecular Function	GO:0044325	transmembrane transporter binding	Kcnip3	IPI	RGD:68394	Rat	PMID:21147063|RGD:7207197
Cellular Component	GO:0030424	axon	Kcnip3	IDA		Rat	PMID:12654510|RGD:7207201
Cellular Component	GO:0043679	axon terminus	Kcnip3	IDA		Rat	PMID:12654510|RGD:7207201
Cellular Component	GO:0005829	cytosol	Kcnip3	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Cellular Component	GO:0005829	cytosol	Kcnip3	IDA		Mouse	PMID:17189291
Cellular Component	GO:0030425	dendrite	Kcnip3	IDA		Rat	PMID:12654510|RGD:7207201
Cellular Component	GO:0005634	nucleus	Kcnip3	IDA		Mouse	PMID:17189291
Cellular Component	GO:0005634	nucleus	Kcnip3	IDA		Rat	PMID:18191896|RGD:7207199
Cellular Component	GO:0032993	protein-DNA complex	Kcnip3	IMP		Mouse	MGI:MGI:5882899|PMID:15746104
Cellular Component	GO:0032993	protein-DNA complex	Kcnip3	IDA		Rat	PMID:18191896|RGD:7207199
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnip3	IDA		Mouse	MGI:MGI:4837570|PMID:20943905
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcnip3	IDA		Mouse	MGI:MGI:5616313|PMID:19713751
Biological Process	GO:0048266	behavioral response to pain	Kcnip3	IMP	MGI:MGI:2679303	Mouse	PMID:14534243
Biological Process	GO:0031018	endocrine pancreas development	kcnip3b	IMP	ZFIN:ZDB-MRPHLNO-070802-2	Zfish	PMID:17450605
Biological Process	GO:0031018	endocrine pancreas development	kcnip3b	IMP	ZFIN:ZDB-MRPHLNO-070802-1	Zfish	PMID:17450605
Biological Process	GO:0006886	intracellular protein transport	Kcnip3	IMP		Rat	PMID:12829703|RGD:1299235
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	KCNIP3	IDA		Human	PMID:10078534
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Kcnip3	IMP	MGI:MGI:2179103	Mouse	PMID:11792319
Biological Process	GO:0072659	protein localization to plasma membrane	Kcnip3	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Biological Process	GO:0043523	regulation of neuron apoptotic process	Kcnip3	IDA		Mouse	PMID:17189291
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	Kcnip3	IMP		Mouse	MGI:MGI:4837570|PMID:20943905
Biological Process	GO:0032026	response to magnesium ion	Kcnip3	IMP		Mouse	MGI:MGI:5882899|PMID:15746104
Biological Process	GO:0048265	response to pain	Kcnip3	IMP	MGI:MGI:2179103	Mouse	PMID:11792319
Biological Process	GO:0019233	sensory perception of pain	Kcnip3	IMP	MGI:MGI:2179103	Mouse	PMID:11792319

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern