Comparative GO Graph (mouse, human)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNQ1OT1
  • Mouse genes Kcnq1ot1
  • Rat genes
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcnq1ot1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Kcnq1ot1	IDA		Mouse	PMID:20573698
Molecular Function	GO:0035198	miRNA binding	Kcnq1ot1	IDA		Mouse	PMID:32060985
Molecular Function	GO:0005515	protein binding	Kcnq1ot1	IPI	PR:P13864	Mouse	PMID:20573698
Molecular Function	GO:0044877	protein-containing complex binding	Kcnq1ot1	IDA		Mouse	PMID:21172659
Biological Process	GO:1902742	apoptotic process involved in development	Kcnq1ot1	IMP		Mouse	PMID:32060985
Biological Process	GO:0016477	cell migration	Kcnq1ot1	IMP		Mouse	PMID:32060985
Biological Process	GO:0010467	gene expression	Kcnq1ot1	IMP		Mouse	PMID:32060985
Biological Process	GO:0080188	gene silencing by RNA-directed DNA methylation	Kcnq1ot1	IMP	MGI:MGI:4830272	Mouse	PMID:20573698
Biological Process	GO:0080188	gene silencing by RNA-directed DNA methylation	Kcnq1ot1	IDA		Mouse	PMID:15340049
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	Kcnq1ot1	IDA		Mouse	PMID:15340049
Biological Process	GO:0044027	negative regulation of gene expression via CpG island methylation	Kcnq1ot1	IMP	MGI:MGI:4830272	Mouse	PMID:20573698
Biological Process	GO:0033687	osteoblast proliferation	Kcnq1ot1	IMP		Mouse	PMID:32060985
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Kcnq1ot1	IMP	MGI:MGI:3773025	Mouse	PMID:20573698
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Kcnq1ot1	IDA		Mouse	PMID:15340049

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern