Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCNS1
  • Mouse genes Kcns1
  • Rat genes Kcns1
  • Zfish genes si:dkey-43k4.5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kcns1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005251	delayed rectifier potassium channel activity	KCNS1	IDA		Human	PMID:10484328
Molecular Function	GO:0015459	potassium channel regulator activity	KCNS1	IDA		Human	PMID:10484328
Molecular Function	GO:0005515	protein binding	KCNS1	IPI	UniProtKB:Q14721	Human	PMID:10484328
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Kcns1	IDA		Mouse	MGI:MGI:1097310|PMID:9305895
Cellular Component	GO:0005886	plasma membrane	KCNS1	IDA		Human	PMID:10484328
Cellular Component	GO:0005886	plasma membrane	Kcns1	IDA		Mouse	MGI:MGI:1097310|PMID:9305895
Cellular Component	GO:0008076	voltage-gated potassium channel complex	KCNS1	IDA		Human	PMID:10484328
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Kcns1	IDA		Mouse	MGI:MGI:1097310|PMID:9305895
Biological Process	GO:0006813	potassium ion transport	Kcns1	IDA		Mouse	MGI:MGI:1097310|PMID:9305895
Biological Process	GO:1902259	regulation of delayed rectifier potassium channel activity	Kcns1	IDA		Mouse	MGI:MGI:1097310|PMID:9305895

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern