Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD10
  • Mouse genes Kctd10
  • Rat genes Kctd10
  • Zfish genes kctd10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	KCTD10	IPI	UniProtKB:Q9H3F6	Human	PMID:32296183
Molecular Function	GO:0005112	Notch binding	KCTD10	IPI	UniProtKB:P46531	Human	PMID:25401743
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q8WZ19	Human	PMID:19615732
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q13618	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q13618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q13829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q8IYF3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q8WZ19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD10	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q8BZ64	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q2MV57	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q3UK10	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q8K0U3	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q5SW45	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q8CFW7	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q8K3E5	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q3U284	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	Kctd10	IPI	PR:Q9R1S0	Mouse	PMID:22179047
Molecular Function	GO:0005515	protein binding	kctd10	IPI	ZFIN:ZDB-GENE-991124-7	Zfish	PMID:24430697
Molecular Function	GO:0003714	transcription corepressor activity	kctd10	IPI	ZFIN:ZDB-GENE-991124-7	Zfish	PMID:24430697
Cellular Component	GO:0005829	cytosol	KCTD10	IDA		Human	GO_REF:0000052
Cellular Component	GO:0036038	MKS complex	Kctd10	IDA		Mouse	PMID:22179047
Cellular Component	GO:0005654	nucleoplasm	KCTD10	IDA		Human	GO_REF:0000052
Biological Process	GO:0001525	angiogenesis	Kctd10	IMP	MGI:MGI:5751542	Mouse	PMID:25401743
Biological Process	GO:0036302	atrioventricular canal development	kctd10	IGI	ZFIN:ZDB-GENE-020828-1	Zfish	PMID:24430697
Biological Process	GO:0036302	atrioventricular canal development	kctd10	IGI	ZFIN:ZDB-GENE-991124-7	Zfish	PMID:24430697
Biological Process	GO:0036302	atrioventricular canal development	kctd10	IMP	ZFIN:ZDB-GENO-151013-11	Zfish	PMID:24430697
Biological Process	GO:0003157	endocardium development	kctd10	IMP	ZFIN:ZDB-GENO-151013-11	Zfish	PMID:24430697
Biological Process	GO:0007507	heart development	Kctd10	IMP	MGI:MGI:5751542	Mouse	PMID:25401743
Biological Process	GO:0007507	heart development	kctd10	IMP	ZFIN:ZDB-MRPHLNO-160912-1	Zfish	PMID:24705121
Biological Process	GO:0001947	heart looping	kctd10	IGI	ZFIN:ZDB-GENE-991124-7	Zfish	PMID:24430697
Biological Process	GO:0001947	heart looping	kctd10	IGI	ZFIN:ZDB-GENE-020828-1	Zfish	PMID:24430697
Biological Process	GO:0001947	heart looping	kctd10	IMP	ZFIN:ZDB-GENO-151013-11	Zfish	PMID:24430697
Biological Process	GO:0043433	negative regulation of DNA-binding transcription factor activity	kctd10	IDA		Zfish	PMID:24430697
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	Kctd10	IMP	MGI:MGI:5751542	Mouse	PMID:25401743
Biological Process	GO:0033339	pectoral fin development	kctd10	IMP	ZFIN:ZDB-GENO-151013-11	Zfish	PMID:24430697
Biological Process	GO:1900125	regulation of hyaluronan biosynthetic process	kctd10	IMP	ZFIN:ZDB-GENO-151013-11	Zfish	PMID:24430697
Biological Process	GO:0002040	sprouting angiogenesis	kctd10	IMP	ZFIN:ZDB-MRPHLNO-160912-1	Zfish	PMID:24705121
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	KCTD10	IDA		Human	PMID:25401743

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern