Comparative GO Graph (mouse, human, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD12
  • Mouse genes Kctd12
  • Rat genes
  • Zfish genes kctd12.1,kctd12.2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd12

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	KCTD12	IPI	UniProtKB:Q96CX2	Human	PMID:27152988
Molecular Function	GO:0005515	protein binding	KCTD12	IPI	UniProtKB:Q3KQV3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Kctd12	IPI	PR:Q9WV18	Mouse	PMID:20400944
Molecular Function	GO:0005515	protein binding	kctd12.1	IPI	ZFIN:ZDB-GENE-090218-30	Zfish	PMID:25329151
Molecular Function	GO:0003723	RNA binding	KCTD12	HDA		Human	PMID:22681889
Cellular Component	GO:0045211	postsynaptic membrane	Kctd12	IDA		Mouse	PMID:20400944
Cellular Component	GO:0042734	presynaptic membrane	Kctd12	IDA		Mouse	PMID:20400944
Cellular Component	GO:0043235	receptor complex	Kctd12	IDA		Mouse	PMID:20400944
Biological Process	GO:0021986	habenula development	kctd12.1	IMP	ZFIN:ZDB-GENO-110826-4	Zfish	PMID:21734278
Biological Process	GO:0021986	habenula development	kctd12.1	IGI	ZFIN:ZDB-GENO-110826-4,ZFIN:ZDB-MRPHLNO-110825-3	Zfish	PMID:21734278
Biological Process	GO:0021986	habenula development	kctd12.2	IMP	ZFIN:ZDB-GENO-110725-5	Zfish	PMID:21734278
Biological Process	GO:0048814	regulation of dendrite morphogenesis	kctd12.1	IGI	ZFIN:ZDB-GENO-110826-4,ZFIN:ZDB-MRPHLNO-110825-3	Zfish	PMID:21734278
Biological Process	GO:0048814	regulation of dendrite morphogenesis	kctd12.1	IMP	ZFIN:ZDB-GENO-110826-4	Zfish	PMID:21734278
Biological Process	GO:0048814	regulation of dendrite morphogenesis	kctd12.2	IMP	ZFIN:ZDB-GENO-110725-5	Zfish	PMID:21734278
Biological Process	GO:0008277	regulation of G protein-coupled receptor signaling pathway	Kctd12	IGI	MGI:MGI:1860139	Mouse	PMID:20400944

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern