Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD21
  • Mouse genes Kctd21
  • Rat genes Kctd21
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd21

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097602	cullin family protein binding	KCTD21	IDA		Human	PMID:21472142
Molecular Function	GO:0042826	histone deacetylase binding	KCTD21	IDA		Human	PMID:21472142
Molecular Function	GO:0042802	identical protein binding	KCTD21	IPI	UniProtKB:Q4G0X4	Human	PMID:21472142
Molecular Function	GO:0042802	identical protein binding	KCTD21	IPI	UniProtKB:Q4G0X4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:O60437	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:P61960	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q17RB8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q8IUI8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q8WYQ4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q96BH1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q96E35	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD21	IPI	UniProtKB:Q9NWW6	Human	PMID:32296183
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	KCTD21	IDA		Human	PMID:21472142
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	KCTD21	IDA		Human	PMID:21472142

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern