Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KCTD6
  • Mouse genes Kctd6
  • Rat genes Kctd6
  • Zfish genes kctd6a,kctd6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kctd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030506	ankyrin binding	KCTD6	IDA		Human	PMID:22573887
Molecular Function	GO:0097602	cullin family protein binding	KCTD6	IDA		Human	PMID:21472142
Molecular Function	GO:0042802	identical protein binding	KCTD6	IPI	UniProtKB:Q8NC69	Human	PMID:21472142
Molecular Function	GO:0042802	identical protein binding	KCTD6	IPI	UniProtKB:Q8NC69	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	KCTD6	IPI	UniProtKB:Q8NC69	Human	PMID:27152988
Molecular Function	GO:0042802	identical protein binding	KCTD6	IPI	UniProtKB:Q8NC69	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q13618	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:B2R8Y4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:O60716-29	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P12814	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P57764	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q08426	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q08AF8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q0D2H9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q13427	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q13618	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q14451	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8TBB1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8TBK6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8WWY3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9H5Z6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9H7E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9UJX2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8WWY3	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q13618	Human	PMID:27152988
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P51784	Human	PMID:29293652
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8TBB1	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P57764	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q08426	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8WWY3	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:O00560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:O60716-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P00540	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:P57764	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q13618	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q14451-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8N8B7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q8WWY3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q96N21	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9BYX2-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KCTD6	IPI	UniProtKB:Q9UJX2	Human	PMID:32296183
Biological Process	GO:0045879	negative regulation of smoothened signaling pathway	KCTD6	IDA		Human	PMID:21472142
Biological Process	GO:0006511	ubiquitin-dependent protein catabolic process	KCTD6	IDA		Human	PMID:21472142

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern