Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDF1
  • Mouse genes Kdf1
  • Rat genes Kdf1
  • Zfish genes kdf1a,kdf1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	KDF1	IPI	UniProtKB:P78424	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KDF1	IPI	UniProtKB:Q03989	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KDF1	IPI	UniProtKB:Q8TD10	Human	PMID:32296183
Cellular Component	GO:0005938	cell cortex	Kdf1	IDA		Mouse	PMID:24075906
Cellular Component	GO:0030054	cell junction	Kdf1	IDA		Mouse	MGI:MGI:5529391|PMID:24075906
Cellular Component	GO:0031252	cell leading edge	Kdf1	IDA		Mouse	PMID:24075906
Cellular Component	GO:0005737	cytoplasm	Kdf1	IDA		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0048589	developmental growth	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0061436	establishment of skin barrier	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0003334	keratinocyte development	Kdf1	IMP	MGI:MGI:5559501	Mouse	PMID:24075906
Biological Process	GO:0003334	keratinocyte development	Kdf1	IGI	MGI:MGI:1891831	Mouse	PMID:24075906
Biological Process	GO:0043616	keratinocyte proliferation	Kdf1	IGI	MGI:MGI:1330810	Mouse	PMID:24075906
Biological Process	GO:0043616	keratinocyte proliferation	Kdf1	IMP	MGI:MGI:5559501	Mouse	PMID:24075906
Biological Process	GO:0043616	keratinocyte proliferation	Kdf1	IGI	MGI:MGI:1891831	Mouse	PMID:24075906
Biological Process	GO:0060887	limb epidermis development	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0016331	morphogenesis of embryonic epithelium	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Kdf1	IGI	MGI:MGI:1330810	Mouse	PMID:24075906
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Kdf1	IMP	MGI:MGI:5559501	Mouse	PMID:24075906
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Kdf1	IGI	MGI:MGI:1891831	Mouse	PMID:24075906
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Kdf1	IGI	MGI:MGI:1891831	Mouse	PMID:24075906
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Kdf1	IGI	MGI:MGI:1330810	Mouse	PMID:24075906
Biological Process	GO:2000647	negative regulation of stem cell proliferation	Kdf1	IMP	MGI:MGI:5559501	Mouse	PMID:24075906
Biological Process	GO:0045606	positive regulation of epidermal cell differentiation	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0010482	regulation of epidermal cell division	Kdf1	IMP		Mouse	MGI:MGI:5529391|PMID:24075906
Biological Process	GO:0072089	stem cell proliferation	Kdf1	IGI	MGI:MGI:1330810	Mouse	PMID:24075906
Biological Process	GO:0072089	stem cell proliferation	Kdf1	IMP	MGI:MGI:5559501	Mouse	PMID:24075906
Biological Process	GO:0072089	stem cell proliferation	Kdf1	IGI	MGI:MGI:1891831	Mouse	PMID:24075906

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern