Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KDM3A
  • Mouse genes Kdm3a
  • Rat genes Kdm3a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kdm3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Kdm3a	IDA		Mouse	PMID:17991879
Molecular Function	GO:0003682	chromatin binding	Kdm3a	IDA		Mouse	PMID:17943087
Molecular Function	GO:0032454	histone H3K9 demethylase activity	KDM3A	IMP		Human	PMID:28262558
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm3a	IMP		Mouse	PMID:17938240
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm3a	IDA		Mouse	PMID:17991879
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm3a	IMP		Mouse	PMID:17991879
Molecular Function	GO:0032454	histone H3K9 demethylase activity	Kdm3a	IMP	MGI:MGI:3764891	Mouse	PMID:17943087
Molecular Function	GO:0140683	histone H3K9me/H3K9me2 demethylase activity	KDM3A	IDA		Human	PMID:16603237
Molecular Function	GO:0005506	iron ion binding	KDM3A	IMP		Human	PMID:16603237
Molecular Function	GO:0050681	nuclear androgen receptor binding	KDM3A	IDA		Human	PMID:16603237
Molecular Function	GO:0005515	protein binding	KDM3A	IPI	UniProtKB:O75582	Human	PMID:25535969
Molecular Function	GO:0005515	protein binding	KDM3A	IPI	UniProtKB:O75582-1	Human	PMID:25535969
Molecular Function	GO:0005515	protein binding	KDM3A	IPI	UniProtKB:P42224-1	Human	PMID:25535969
Molecular Function	GO:0005515	protein binding	Kdm3a	IPI	PR:Q8K4J6	Mouse	PMID:17991879
Molecular Function	GO:0005515	protein binding	Kdm3a	IPI	PR:Q8VIM5	Mouse	PMID:17991879
Molecular Function	GO:0005515	protein binding	Kdm3a	IPI	PR:P59759	Mouse	PMID:17991879
Molecular Function	GO:0003712	transcription coregulator activity	Kdm3a	IDA		Mouse	PMID:17991879
Cellular Component	GO:0005737	cytoplasm	Kdm3a	IDA		Mouse	PMID:17943087
Cellular Component	GO:0001673	male germ cell nucleus	Kdm3a	IDA		Mouse	PMID:17943087
Cellular Component	GO:0016020	membrane	KDM3A	HDA		Human	PMID:19946888
Cellular Component	GO:0005654	nucleoplasm	KDM3A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	KDM3A	IDA		Human	PMID:16603237
Cellular Component	GO:0005634	nucleus	Kdm3a	IDA		Mouse	PMID:17599069
Biological Process	GO:0030521	androgen receptor signaling pathway	KDM3A	IDA		Human	PMID:16603237
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Kdm3a	IEP		Mouse	PMID:20439489
Biological Process	GO:0046293	formaldehyde biosynthetic process	KDM3A	IDA		Human	PMID:16603237
Biological Process	GO:0016570	histone modification	Kdm3a	IMP		Mouse	MGI:MGI:3759699|PMID:17938240
Biological Process	GO:0009755	hormone-mediated signaling pathway	KDM3A	IDA		Human	PMID:16603237
Biological Process	GO:0008584	male gonad development	Kdm3a	IEP		Rat	PMID:1793593|RGD:1299385
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Kdm3a	IMP		Mouse	MGI:MGI:3840035|PMID:19194461
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	KDM3A	IMP		Human	PMID:16603237
Biological Process	GO:0010628	positive regulation of gene expression	Kdm3a	IMP		Rat	PMID:18538129|RGD:9586363
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Kdm3a	IDA		Mouse	PMID:17991879
Biological Process	GO:0010468	regulation of gene expression	Kdm3a	IMP		Mouse	PMID:17938240
Biological Process	GO:2000736	regulation of stem cell differentiation	Kdm3a	IMP		Mouse	PMID:17938240
Biological Process	GO:2000036	regulation of stem cell population maintenance	Kdm3a	IGI	MGI:MGI:1097166	Mouse	PMID:17938240
Biological Process	GO:0001666	response to hypoxia	Kdm3a	IEP		Rat	PMID:18538129|RGD:9586363
Biological Process	GO:0007290	spermatid nucleus elongation	Kdm3a	IMP	MGI:MGI:3764891	Mouse	PMID:17943087
Biological Process	GO:0007283	spermatogenesis	Kdm3a	IMP	MGI:MGI:3764891	Mouse	PMID:17943087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern