Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KEL
  • Mouse genes Kel
  • Rat genes Kel
  • Zfish genes kel
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kel

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004222	metalloendopeptidase activity	KEL	IDA		Human	PMID:15769748
Molecular Function	GO:0008237	metallopeptidase activity	Kel	IMP	MGI:MGI:5581644	Mouse	PMID:19544475
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:P01031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:Q15848	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:Q5BVD1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:Q8IYS1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:P17612	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:P37173	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:P50454	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KEL	IPI	UniProtKB:P51811	Human	PMID:7737196
Cellular Component	GO:0005829	cytosol	KEL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	KEL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Kel	IDA		Mouse	PMID:19544475
Cellular Component	GO:0005654	nucleoplasm	KEL	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KEL	IDA		Human	GO_REF:0000052
Biological Process	GO:0051649	establishment of localization in cell	Kel	IGI	MGI:MGI:95285	Mouse	PMID:19544475
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Kel	IGI	MGI:MGI:103569	Mouse	PMID:23122227
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Kel	IGI	MGI:MGI:95285	Mouse	PMID:23122227
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	Kel	IGI	MGI:MGI:95285	Mouse	PMID:23122227
Biological Process	GO:0010961	intracellular magnesium ion homeostasis	Kel	IGI	MGI:MGI:103569	Mouse	PMID:23122227
Biological Process	GO:0042552	myelination	Kel	IMP	MGI:MGI:5581644	Mouse	PMID:24405768
Biological Process	GO:1901380	negative regulation of potassium ion transmembrane transport	Kel	IGI	MGI:MGI:95285	Mouse	PMID:19544475
Biological Process	GO:0071805	potassium ion transmembrane transport	Kel	IGI	MGI:MGI:95285	Mouse	PMID:19544475
Biological Process	GO:0031133	regulation of axon diameter	Kel	IGI	MGI:MGI:103569	Mouse	PMID:24405768
Biological Process	GO:0008361	regulation of cell size	Kel	IGI	MGI:MGI:103569	Mouse	PMID:23122227
Biological Process	GO:0048741	skeletal muscle fiber development	Kel	IGI	MGI:MGI:103569	Mouse	PMID:24405768

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern