Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KHSRP
  • Mouse genes Khsrp
  • Rat genes Khsrp
  • Zfish genes khsrp
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Khsrp

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	KHSRP	IDA		Human	PMID:16126846
Molecular Function	GO:0035925	mRNA 3'-UTR AU-rich region binding	khsrp	IDA		Zfish	PMID:31227602
Molecular Function	GO:0003730	mRNA 3'-UTR binding	Khsrp	IDA		Rat	PMID:12358751|RGD:724414
Molecular Function	GO:0003729	mRNA binding	Khsrp	IDA		Mouse	PMID:22844247
Molecular Function	GO:0005515	protein binding	KHSRP	IPI	UniProtKB:P26651	Human	PMID:16126846
Molecular Function	GO:0005515	protein binding	KHSRP	IPI	UniProtKB:P63101	Human	PMID:17437629
Molecular Function	GO:0005515	protein binding	KHSRP	IPI	UniProtKB:P63101	Human	PMID:19198587
Molecular Function	GO:0005515	protein binding	KHSRP	IPI	UniProtKB:Q9UPY3-1	Human	PMID:19458619
Molecular Function	GO:0005515	protein binding	Khsrp	IPI	UniProtKB:Q923K9	Rat	PMID:10781591|RGD:8553657
Molecular Function	GO:0044183	protein folding chaperone	KHSRP	EXP		Human	PMID:19198587
Molecular Function	GO:0003723	RNA binding	KHSRP	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	KHSRP	HDA		Human	PMID:22681889
Cellular Component	GO:0010494	cytoplasmic stress granule	Khsrp	IDA		Mouse	PMID:21933836
Cellular Component	GO:0030425	dendrite	Khsrp	IDA		Rat	PMID:12358751|RGD:724414
Cellular Component	GO:0016020	membrane	KHSRP	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Khsrp	IDA		Rat	PMID:12358751|RGD:724414
Cellular Component	GO:0005654	nucleoplasm	KHSRP	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Khsrp	IDA		Rat	PMID:12358751|RGD:724414
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	KHSRP	IDA		Human	PMID:16126846
Biological Process	GO:0061158	3'-UTR-mediated mRNA destabilization	KHSRP	IMP		Human	PMID:28275056
Biological Process	GO:0071345	cellular response to cytokine stimulus	KHSRP	IMP		Human	PMID:16126846
Biological Process	GO:0010586	miRNA metabolic process	KHSRP	IMP		Human	PMID:27478153
Biological Process	GO:0006402	mRNA catabolic process	Khsrp	IDA		Mouse	PMID:22844247
Biological Process	GO:0010989	negative regulation of low-density lipoprotein particle clearance	KHSRP	IGI	RNAcentral:URS00004176D4_9606	Human	PMID:26523989
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	KHSRP	IDA		Human	PMID:16126846
Biological Process	GO:0061014	positive regulation of mRNA catabolic process	KHSRP	IDA		Human	PMID:16126846
Biological Process	GO:2000628	regulation of miRNA metabolic process	Khsrp	IDA		Mouse	PMID:22844247
Biological Process	GO:0043488	regulation of mRNA stability	KHSRP	IDA		Human	PMID:16126846

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern