Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIDINS220
  • Mouse genes Kidins220
  • Rat genes Kidins220
  • Zfish genes kidins220a,kidins220b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kidins220

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030165	PDZ domain binding	Kidins220	IDA		Rat	PMID:17724123|RGD:8554481
Molecular Function	GO:0030165	PDZ domain binding	kidins220b	IPI	ZFIN:ZDB-GENE-071022-4	Zfish	PMID:22609016
Molecular Function	GO:0005515	protein binding	Kidins220	IPI	UniProtKB:P46109	Rat	PMID:16284401|RGD:8553374
Molecular Function	GO:0005515	protein binding	Kidins220	IPI	UniProtKB:F1M386	Rat	PMID:17724123|RGD:8554481
Molecular Function	GO:0005515	protein binding	Kidins220	IPI	UniProtKB:O88382-1	Rat	PMID:17724123|RGD:8554481
Molecular Function	GO:0019901	protein kinase binding	Kidins220	IDA		Rat	PMID:11150334|RGD:633108
Molecular Function	GO:0019887	protein kinase regulator activity	Kidins220	IDA		Rat	PMID:11150334|RGD:633108
Cellular Component	GO:0005770	late endosome	Kidins220	IDA		Rat	PMID:17724123|RGD:8554481
Cellular Component	GO:0016020	membrane	KIDINS220	HDA		Human	PMID:19946888
Cellular Component	GO:0032991	protein-containing complex	Kidins220	IDA		Rat	PMID:17724123|RGD:8554481
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Kidins220	IDA		Rat	PMID:17724123|RGD:8554481
Biological Process	GO:0048813	dendrite morphogenesis	Kidins220	IMP	MGI:MGI:4820793	Mouse	PMID:19449316
Biological Process	GO:0001701	in utero embryonic development	Kidins220	IMP	MGI:MGI:4820793	Mouse	PMID:19449316
Biological Process	GO:0038180	nerve growth factor signaling pathway	Kidins220	IDA		Rat	PMID:17724123|RGD:8554481
Biological Process	GO:0010976	positive regulation of neuron projection development	Kidins220	IMP		Rat	PMID:17724123|RGD:8554481

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern