Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF14
  • Mouse genes Kif14
  • Rat genes Kif14
  • Zfish genes kif14
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif14

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	Kif14	IDA		Mouse	MGI:MGI:5607363|PMID:24949858
Molecular Function	GO:0016887	ATP hydrolysis activity	Kif14	IDA		Mouse	MGI:MGI:5607363|PMID:24949858
Molecular Function	GO:0008017	microtubule binding	Kif14	IDA		Mouse	MGI:MGI:5607363|PMID:24949858
Molecular Function	GO:0030165	PDZ domain binding	KIF14	IDA		Human	PMID:23209302
Molecular Function	GO:0008574	plus-end-directed microtubule motor activity	Kif14	IDA		Mouse	MGI:MGI:5607363|PMID:24949858
Molecular Function	GO:0005515	protein binding	KIF14	IPI	UniProtKB:O43663	Human	PMID:16431929
Molecular Function	GO:0005515	protein binding	KIF14	IPI	UniProtKB:P32121	Human	PMID:16820410
Molecular Function	GO:0005515	protein binding	KIF14	IPI	UniProtKB:O46385	Human	PMID:20309963
Molecular Function	GO:0019901	protein kinase binding	KIF14	IPI	UniProtKB:O14578	Human	PMID:16431929
Molecular Function	GO:0019901	protein kinase binding	KIF14	IPI	UniProtKB:P31749	Human	PMID:24784001
Molecular Function	GO:0015631	tubulin binding	Kif14	IDA		Mouse	MGI:MGI:5607363|PMID:24949858
Cellular Component	GO:0005829	cytosol	KIF14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0090543	Flemming body	KIF14	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	KIF14	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	KIF14	IDA		Human	PMID:23209302
Cellular Component	GO:0030496	midbody	KIF14	IDA		Human	PMID:16431929
Cellular Component	GO:0030496	midbody	KIF14	IDA		Human	PMID:20309963
Cellular Component	GO:0005886	plasma membrane	KIF14	IPI	UniProtKB:P31749	Human	PMID:24784001
Cellular Component	GO:0051233	spindle midzone	KIF14	IDA		Human	PMID:16431929
Biological Process	GO:0032147	activation of protein kinase activity	KIF14	IMP		Human	PMID:24784001
Biological Process	GO:0007420	brain development	kif14	IMP	ZFIN:ZDB-GENO-201222-8	Zfish	PMID:30388224
Biological Process	GO:0007420	brain development	kif14	IMP	ZFIN:ZDB-MRPHLNO-201201-1	Zfish	PMID:30388224
Biological Process	GO:0051301	cell division	Kif14	IMP		Mouse	MGI:MGI:5605219|PMID:24931760
Biological Process	GO:0021846	cell proliferation in forebrain	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0021695	cerebellar cortex development	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0021685	cerebellar granular layer structural organization	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0021693	cerebellar Purkinje cell layer structural organization	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0021987	cerebral cortex development	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0045184	establishment of protein localization	KIF14	IDA		Human	PMID:23209302
Biological Process	GO:0021766	hippocampus development	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0001822	kidney development	kif14	IMP	ZFIN:ZDB-GENO-201222-8	Zfish	PMID:30388224
Biological Process	GO:0001822	kidney development	kif14	IMP	ZFIN:ZDB-MRPHLNO-201201-1	Zfish	PMID:30388224
Biological Process	GO:0007080	mitotic metaphase plate congression	KIF14	IMP		Human	PMID:15843429
Biological Process	GO:0043066	negative regulation of apoptotic process	KIF14	IMP		Human	PMID:24784001
Biological Process	GO:0033624	negative regulation of integrin activation	KIF14	IMP		Human	PMID:23209302
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0021772	olfactory bulb development	Kif14	IMP		Mouse	MGI:MGI:5605219|PMID:24931760
Biological Process	GO:0021772	olfactory bulb development	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0008284	positive regulation of cell population proliferation	KIF14	IDA		Human	PMID:24784001
Biological Process	GO:0008284	positive regulation of cell population proliferation	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0032467	positive regulation of cytokinesis	KIF14	IMP		Human	PMID:16431929
Biological Process	GO:0032467	positive regulation of cytokinesis	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0030155	regulation of cell adhesion	KIF14	IMP		Human	PMID:23209302
Biological Process	GO:0001558	regulation of cell growth	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:1903429	regulation of cell maturation	Kif14	IMP		Mouse	MGI:MGI:5605219|PMID:24931760
Biological Process	GO:0030334	regulation of cell migration	KIF14	IMP		Human	PMID:23209302
Biological Process	GO:2000045	regulation of G1/S transition of mitotic cell cycle	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0010389	regulation of G2/M transition of mitotic cell cycle	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0031641	regulation of myelination	Kif14	IMP		Mouse	MGI:MGI:5485315|PMID:23308235
Biological Process	GO:0031641	regulation of myelination	Kif14	IMP		Mouse	MGI:MGI:5605219|PMID:24931760
Biological Process	GO:0043523	regulation of neuron apoptotic process	Kif14	IMP		Mouse	MGI:MGI:5605219|PMID:24931760
Biological Process	GO:0032487	regulation of Rap protein signal transduction	KIF14	IMP		Human	PMID:23209302
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	KIF14	IMP		Human	PMID:24854087
Biological Process	GO:0034446	substrate adhesion-dependent cell spreading	KIF14	IDA		Human	PMID:23209302

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern