Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF18A
  • Mouse genes Kif18a
  • Rat genes Kif18a
  • Zfish genes kif18a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif18a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003779	actin binding	KIF18A	IPI	UniProtKB:P60709	Human	PMID:18680169
Molecular Function	GO:0008017	microtubule binding	KIF18A	IDA		Human	PMID:18680169
Molecular Function	GO:0051010	microtubule plus-end binding	KIF18A	IDA		Human	PMID:17346968
Molecular Function	GO:0008574	plus-end-directed microtubule motor activity	KIF18A	IDA		Human	PMID:17346968
Molecular Function	GO:0005515	protein binding	KIF18A	IPI	UniProtKB:P62136	Human	PMID:15231748
Molecular Function	GO:0005515	protein binding	KIF18A	IPI	UniProtKB:P03372	Human	PMID:17006958
Molecular Function	GO:0005515	protein binding	KIF18A	IPI	UniProtKB:Q9UJX5	Human	PMID:23288039
Molecular Function	GO:0005515	protein binding	KIF18A	IPI	UniProtKB:P62136	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	KIF18A	IPI	UniProtKB:P62136	Human	PMID:28514442
Molecular Function	GO:0070463	tubulin-dependent ATPase activity	KIF18A	IDA		Human	PMID:17346968
Cellular Component	GO:0005901	caveola	KIF18A	IDA		Human	PMID:17006958
Cellular Component	GO:0005737	cytoplasm	KIF18A	IDA		Human	PMID:17006958
Cellular Component	GO:0005737	cytoplasm	KIF18A	IDA		Human	PMID:18680169
Cellular Component	GO:0000776	kinetochore	Kif18a	IDA		Mouse	PMID:20981276
Cellular Component	GO:0005828	kinetochore microtubule	KIF18A	IDA		Human	PMID:17346968
Cellular Component	GO:0015630	microtubule cytoskeleton	KIF18A	IDA		Human	GO_REF:0000054
Cellular Component	GO:1990023	mitotic spindle midzone	Kif18a	IDA		Mouse	PMID:20981276
Cellular Component	GO:0005634	nucleus	KIF18A	IDA		Human	PMID:17006958
Cellular Component	GO:0005634	nucleus	KIF18A	IDA		Human	PMID:17346968
Cellular Component	GO:0005634	nucleus	KIF18A	IDA		Human	PMID:18680169
Cellular Component	GO:0001726	ruffle	KIF18A	IDA		Human	PMID:17006958
Biological Process	GO:0071392	cellular response to estradiol stimulus	Kif18a	IEP		Rat	PMID:19636373|RGD:11554201
Biological Process	GO:0007140	male meiotic nuclear division	Kif18a	IMP	MGI:MGI:5575486	Mouse	PMID:20981276
Biological Process	GO:0007019	microtubule depolymerization	KIF18A	IDA		Human	PMID:17346968
Biological Process	GO:0007080	mitotic metaphase plate congression	KIF18A	IDA		Human	PMID:17346968
Biological Process	GO:0007080	mitotic metaphase plate congression	Kif18a	IMP		Mouse	PMID:20981276
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	Kif18a	IMP		Mouse	PMID:20981276
Biological Process	GO:0072520	seminiferous tubule development	Kif18a	IMP	MGI:MGI:5575486	Mouse	PMID:20981276

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern