Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF2C
  • Mouse genes Kif2c
  • Rat genes Kif2c
  • Zfish genes kif2c
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif2c

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051010	microtubule plus-end binding	KIF2C	IDA		Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q9H3R5	Human	PMID:11092768
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q15691	Human	PMID:19543227
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q5JR59	Human	PMID:19543227
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q15691	Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q86Y91	Human	PMID:21820309
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q15691	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KIF2C	IPI	UniProtKB:Q15691	Human	PMID:27173435
Cellular Component	GO:0000775	chromosome, centromeric region	KIF2C	IDA		Human	PMID:14960279
Cellular Component	GO:0000775	chromosome, centromeric region	Kif2c	IDA		Mouse	PMID:19283064
Cellular Component	GO:0000776	kinetochore	KIF2C	IDA		Human	PMID:14960279
Cellular Component	GO:0000776	kinetochore	KIF2C	IDA		Human	PMID:23891108
Cellular Component	GO:0016020	membrane	KIF2C	HDA		Human	PMID:19946888
Cellular Component	GO:0015630	microtubule cytoskeleton	KIF2C	IDA		Human	GO_REF:0000054
Cellular Component	GO:0035371	microtubule plus-end	KIF2C	IDA		Human	PMID:21820309
Cellular Component	GO:0035371	microtubule plus-end	KIF2C	IDA		Human	PMID:23891108
Biological Process	GO:0051315	attachment of mitotic spindle microtubules to kinetochore	KIF2C	IMP		Human	PMID:23891108
Biological Process	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	KIF2C	IMP		Human	PMID:14718566
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	kif2c	IMP	ZFIN:ZDB-MRPHLNO-201028-1	Zfish	PMID:32354205
Biological Process	GO:0051310	metaphase plate congression	KIF2C	IMP		Human	PMID:23891108
Biological Process	GO:0007019	microtubule depolymerization	KIF2C	IMP		Human	PMID:19060894
Biological Process	GO:0007019	microtubule depolymerization	KIF2C	IDA		Human	PMID:21820309
Biological Process	GO:0007080	mitotic metaphase plate congression	KIF2C	IMP		Human	PMID:15843429
Biological Process	GO:0051983	regulation of chromosome segregation	KIF2C	IMP		Human	PMID:19060894

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern