Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF3A
  • Mouse genes Kif3a
  • Rat genes Kif3a
  • Zfish genes kif3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif3a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0120170	intraciliary transport particle B binding	Kif3a	IDA		Mouse	PMID:12821668
Molecular Function	GO:0019894	kinesin binding	Kif3a	IPI	RGD:621538	Rat	PMID:9487132|RGD:729208
Molecular Function	GO:0008017	microtubule binding	Kif3a	IDA		Mouse	PMID:17360631
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q92845	Human	PMID:16298999
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:O00203-1	Human	PMID:19934039
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q8TCI5	Human	PMID:20643351
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q9D9W1	Human	PMID:20643351
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q13286	Human	PMID:22261744
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q92845	Human	PMID:24338362
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q9BXF6	Human	PMID:24591568
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q92845	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q92845	Human	PMID:27173435
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q92845	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	KIF3A	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:Q61771	Mouse	MGI:MGI:6387447|PMID:31746486
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:O08788	Mouse	MGI:MGI:5559658|PMID:23386061
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:P97343	Mouse	MGI:MGI:3835232|PMID:19015237
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:Q6A078	Mouse	MGI:MGI:3624140|PMID:16632484
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:P70188	Mouse	MGI:MGI:5431151|PMID:22632975
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:Q6A078	Mouse	MGI:MGI:3759153|PMID:17898177
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:P70188|UniProtKB:Q61771	Mouse	MGI:MGI:3762082|PMID:17825299
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:P70188|UniProtKB:Q61771	Mouse	MGI:MGI:6094788|PMID:19940036
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:Q61771|UniProtKB:Q8VI40	Mouse	MGI:MGI:5554365|PMID:21909995
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	PR:Q99PW8	Mouse	PMID:19384852
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	PR:Q61771	Mouse	PMID:12821668
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	RGD:1310227	Rat	PMID:21698230|RGD:10047152
Molecular Function	GO:0005515	protein binding	Kif3a	IPI	UniProtKB:Q9UHG0	Rat	PMID:21698230|RGD:10047152
Molecular Function	GO:0019903	protein phosphatase binding	KIF3A	IPI	UniProtKB:P49593	Human	PMID:24338362
Molecular Function	GO:0044877	protein-containing complex binding	Kif3a	IPI	RGD:2123|RGD:620374	Rat	PMID:15556865|RGD:1581595
Molecular Function	GO:0031267	small GTPase binding	KIF3A	IPI	UniProtKB:O14966	Human	PMID:26021297
Molecular Function	GO:0030507	spectrin binding	KIF3A	IDA		Human	PMID:23704327
Cellular Component	GO:1904115	axon cytoplasm	Kif3a	IDA		Rat	PMID:15266650|RGD:11049593
Cellular Component	GO:0005930	axoneme	Kif3a	IDA		Rat	PMID:9920666|RGD:1581597
Cellular Component	GO:0005814	centriole	KIF3A	IDA		Human	PMID:23386061
Cellular Component	GO:0005814	centriole	Kif3a	IDA		Mouse	MGI:MGI:5559658|PMID:23386061
Cellular Component	GO:0005813	centrosome	KIF3A	IDA		Human	PMID:16298999
Cellular Component	GO:0005929	cilium	Kif3a	IDA		Mouse	MGI:MGI:5014446|PMID:21670265
Cellular Component	GO:0005929	cilium	Kif3a	IDA		Mouse	PMID:20172860
Cellular Component	GO:0005929	cilium	Kif3a	IDA		Mouse	PMID:17825299
Cellular Component	GO:0070062	extracellular exosome	KIF3A	HDA		Human	PMID:19056867
Cellular Component	GO:0005871	kinesin complex	kif3a	IDA		Zfish	PMID:19384852
Cellular Component	GO:0016939	kinesin II complex	KIF3A	IDA		Human	PMID:16298999
Cellular Component	GO:0016939	kinesin II complex	Kif3a	IDA		Mouse	PMID:19384852
Cellular Component	GO:0015630	microtubule cytoskeleton	KIF3A	IDA		Human	PMID:16298999
Cellular Component	GO:0031514	motile cilium	Kif3a	IDA		Mouse	PMID:10330409
Cellular Component	GO:0043005	neuron projection	Kif3a	IDA		Mouse	PMID:17360631
Cellular Component	GO:0043025	neuronal cell body	Kif3a	IDA		Rat	PMID:9487132|RGD:729208
Cellular Component	GO:0032391	photoreceptor connecting cilium	Kif3a	IDA		Mouse	MGI:MGI:3839506|PMID:19208653
Cellular Component	GO:0097470	ribbon synapse	Kif3a	IDA		Rat	PMID:18523806|RGD:11049590
Cellular Component	GO:0005876	spindle microtubule	KIF3A	IDA		Human	PMID:16298999
Biological Process	GO:0071929	alpha-tubulin acetylation	Kif3a	IMP		Mouse	PMID:27793670
Biological Process	GO:0009952	anterior/posterior pattern specification	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:10220415
Biological Process	GO:0010457	centriole-centriole cohesion	Kif3a	IMP		Mouse	MGI:MGI:5559658|PMID:23386061
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP		Mouse	MGI:MGI:5014446|PMID:21670265
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP		Mouse	MGI:MGI:4888042|PMID:21209331
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP	MGI:MGI:1926500,MGI:MGI:2386464	Mouse	PMID:21703454
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP	MGI:MGI:2386464	Mouse	PMID:18729223
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:10220415
Biological Process	GO:0060271	cilium assembly	Kif3a	IMP		Mouse	PMID:19684112
Biological Process	GO:0060271	cilium assembly	kif3a	IMP	ZFIN:ZDB-GENO-180904-4	Zfish	PMID:28855254
Biological Process	GO:0060271	cilium assembly	kif3a	IMP	ZFIN:ZDB-MRPHLNO-160818-1	Zfish	PMID:31015398
Biological Process	GO:0060271	cilium assembly	kif3a	IMP	ZFIN:ZDB-GENO-161014-1	Zfish	PMID:27038111
Biological Process	GO:0003341	cilium movement	Kif3a	IMP	MGI:2386464	Mouse	PMID:29891944
Biological Process	GO:0021542	dentate gyrus development	Kif3a	IMP	MGI:MGI:2179048,MGI:MGI:2386464	Mouse	PMID:18297065
Biological Process	GO:0007368	determination of left/right symmetry	Kif3a	IMP	MGI:MGI:3580660	Mouse	PMID:15755804
Biological Process	GO:0007368	determination of left/right symmetry	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:10220415
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Kif3a	IMP		Mouse	MGI:MGI:4888042|PMID:21209331
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Kif3a	IGI	MGI:MGI:95728	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:18590716
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:19286674
Biological Process	GO:0021904	dorsal/ventral neural tube patterning	Kif3a	IGI	MGI:MGI:1341070	Mouse	PMID:18590716
Biological Process	GO:0009953	dorsal/ventral pattern formation	Kif3a	IMP	MGI:MGI:3580660	Mouse	PMID:15755804
Biological Process	GO:0036334	epidermal stem cell homeostasis	Kif3a	IMP	MGI:MGI:2386464,MGI:MGI:2446606	Mouse	PMID:21429982
Biological Process	GO:0008544	epidermis development	Kif3a	IMP	MGI:MGI:1926500,MGI:MGI:2386464	Mouse	PMID:21703454
Biological Process	GO:0030900	forebrain development	Kif3a	IMP	MGI:MGI:2386464,MGI:MGI:2386570	Mouse	PMID:28291836
Biological Process	GO:0030900	forebrain development	Kif3a	IMP	MGI:MGI:2386464,MGI:MGI:2686837	Mouse	PMID:28291836
Biological Process	GO:0030900	forebrain development	Kif3a	IMP	MGI:MGI:1932522,MGI:MGI:2386464	Mouse	PMID:28291836
Biological Process	GO:0007507	heart development	Kif3a	IMP	MGI:MGI:2386464	Mouse	PMID:18729223
Biological Process	GO:0001947	heart looping	Kif3a	IMP	MGI:MGI:2181727	Mouse	PMID:10330409
Biological Process	GO:0001701	in utero embryonic development	Kif3a	IGI	MGI:MGI:1329045	Mouse	PMID:19286674
Biological Process	GO:0060122	inner ear receptor cell stereocilium organization	Kif3a	IMP	MGI:MGI:2386464	Mouse	PMID:18066062
Biological Process	GO:0046907	intracellular transport	kif3a	IMP	ZFIN:ZDB-GENO-161014-1	Zfish	PMID:27470972
Biological Process	GO:0043616	keratinocyte proliferation	Kif3a	IMP	MGI:MGI:1926500,MGI:MGI:2386464	Mouse	PMID:21703454
Biological Process	GO:0001822	kidney development	Kif3a	IMP	MGI:MGI:2386464	Mouse	PMID:15067314
Biological Process	GO:0034454	microtubule anchoring at centrosome	Kif3a	IMP		Mouse	MGI:MGI:5559658|PMID:23386061
Biological Process	GO:0044458	motile cilium assembly	Kif3a	IMP	MGI:MGI:2181727	Mouse	PMID:10330409
Biological Process	GO:0061351	neural precursor cell proliferation	Kif3a	IMP	MGI:MGI:2179048,MGI:MGI:2386464	Mouse	PMID:18297065
Biological Process	GO:0021915	neural tube development	Kif3a	IMP	MGI:MGI:2181727	Mouse	PMID:10330409
Biological Process	GO:1905515	non-motile cilium assembly	Kif3a	IMP	MGI:MGI:2179048,MGI:MGI:2386464	Mouse	PMID:18297065
Biological Process	GO:0007219	Notch signaling pathway	kif3a	IMP	ZFIN:ZDB-MRPHLNO-160818-1	Zfish	PMID:31015398
Biological Process	GO:0035845	photoreceptor cell outer segment organization	kif3a	IMP	ZFIN:ZDB-GENO-161014-1	Zfish	PMID:27470972
Biological Process	GO:1905128	positive regulation of axo-dendritic protein transport	Kif3a	IMP		Rat	PMID:20694152|RGD:11060126
Biological Process	GO:0050679	positive regulation of epithelial cell proliferation	Kif3a	IMP	MGI:MGI:1926500,MGI:MGI:2386464	Mouse	PMID:21703454
Biological Process	GO:2000771	positive regulation of establishment or maintenance of cell polarity regulating cell shape	Kif3a	IMP		Rat	PMID:15048131|RGD:11049589
Biological Process	GO:0090316	positive regulation of intracellular protein transport	Kif3a	IMP		Rat	PMID:15048131|RGD:11049589
Biological Process	GO:0010838	positive regulation of keratinocyte proliferation	Kif3a	IMP	MGI:MGI:1926500,MGI:MGI:2386464	Mouse	PMID:21703454
Biological Process	GO:0048260	positive regulation of receptor-mediated endocytosis	Kif3a	IDA		Rat	PMID:15181154|RGD:1581596
Biological Process	GO:1902414	protein localization to cell junction	KIF3A	IMP		Human	PMID:24338362
Biological Process	GO:0015031	protein transport	KIF3A	IMP		Human	PMID:24338362
Biological Process	GO:0034021	response to silicon dioxide	Kif3a	IEP		Rat	PMID:32042332|RGD:155791682
Biological Process	GO:0007224	smoothened signaling pathway	Kif3a	IMP		Mouse	PMID:27793670
Biological Process	GO:0007224	smoothened signaling pathway	Kif3a	IMP	MGI:MGI:1861960	Mouse	PMID:19286674
Biological Process	GO:0007224	smoothened signaling pathway	Kif3a	IMP	MGI:MGI:2179048,MGI:MGI:2386464	Mouse	PMID:18297065

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern