Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KIF5A
  • Mouse genes Kif5a
  • Rat genes Kif5a
  • Zfish genes kif5aa,kif5ab
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kif5a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0019894	kinesin binding	Kif5a	IPI	UniProtKB:P35922	Mouse	MGI:MGI:3798322|PMID:18539120
Molecular Function	GO:0008017	microtubule binding	Kif5a	IDA		Mouse	PMID:17360631
Molecular Function	GO:0005515	protein binding	KIF5A	IPI	UniProtKB:Q921C5	Human	PMID:20386726
Molecular Function	GO:0005515	protein binding	KIF5A	IPI	UniProtKB:Q96NW4	Human	PMID:22705394
Molecular Function	GO:0005515	protein binding	KIF5A	IPI	UniProtKB:Q8R2H7	Human	PMID:24161670
Molecular Function	GO:0005515	protein binding	KIF5A	IPI	UniProtKB:Q969J3	Human	PMID:25898167
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:Q3TXX3	Mouse	MGI:MGI:5606143|PMID:24251978
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:O70585	Mouse	MGI:MGI:2682521|PMID:14600269
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:O70585	Mouse	MGI:MGI:5513089|PMID:22978324
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:O08788	Mouse	MGI:MGI:3804774|PMID:18615096
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:Q96NW4	Mouse	MGI:MGI:5437370|PMID:22705394
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:O95197|UniProtKB:O95292|UniProtKB:P62491|UniProtKB:Q15907|UniProtKB:Q3TXX3|UniProtKB:Q5T4F4|UniProtKB:Q64310|UniProtKB:Q9P0L0	Mouse	MGI:MGI:5795817|PMID:21976701
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	PR:P28738	Mouse	PMID:10964943
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	UniProtKB:P84060	Rat	PMID:14600269|RGD:1304517
Molecular Function	GO:0005515	protein binding	Kif5a	IPI	RGD:631359	Rat	PMID:17202467|RGD:5509811
Molecular Function	GO:0044877	protein-containing complex binding	Kif5a	IPI	RGD:620331|RGD:631359|RGD:621235|RGD:62000	Rat	PMID:17202468|RGD:4107038
Molecular Function	GO:0097110	scaffold protein binding	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0097440	apical dendrite	Kif5a	IDA		Rat	PMID:9349526|RGD:12792964
Cellular Component	GO:0030424	axon	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0090724	central region of growth cone	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0035253	ciliary rootlet	Kif5a	IDA		Mouse	PMID:16018997
Cellular Component	GO:0005737	cytoplasm	Kif5a	IDA		Mouse	PMID:16018997
Cellular Component	GO:0005829	cytosol	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0030425	dendrite	Kif5a	IDA		Mouse	MGI:MGI:5819356|PMID:11986669
Cellular Component	GO:0030425	dendrite	Kif5a	IDA		Rat	PMID:22355657|RGD:6902916
Cellular Component	GO:0030425	dendrite	Kif5a	IDA		Rat	PMID:23487039|RGD:12791272
Cellular Component	GO:0032839	dendrite cytoplasm	Kif5a	IDA		Mouse	MGI:MGI:5819356|PMID:11986669
Cellular Component	GO:0005871	kinesin complex	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0016020	membrane	KIF5A	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	Kif5a	IDA		Rat	PMID:17202468|RGD:4107038
Cellular Component	GO:0043005	neuron projection	Kif5a	IDA		Mouse	PMID:17360631
Cellular Component	GO:0043005	neuron projection	Kif5a	IDA		Mouse	PMID:16301330
Cellular Component	GO:0043025	neuronal cell body	Kif5a	IDA		Mouse	PMID:17360631
Cellular Component	GO:0000932	P-body	Kif5a	IDA		Rat	PMID:23487039|RGD:12791272
Cellular Component	GO:0043204	perikaryon	Kif5a	IDA		Rat	PMID:9349526|RGD:12792964
Biological Process	GO:0099641	anterograde axonal protein transport	Kif5a	IMP		Rat	PMID:23576431|RGD:13673742
Biological Process	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex	Kif5a	IMP		Mouse	PMID:11986669
Biological Process	GO:0098971	anterograde dendritic transport of neurotransmitter receptor complex	Kif5a	IDA		Mouse	PMID:11986669
Biological Process	GO:0019896	axonal transport of mitochondrion	kif5aa	IMP	ZFIN:ZDB-GENO-150210-9	Zfish	PMID:25355224
Biological Process	GO:0071361	cellular response to ethanol	Kif5a	IEP		Rat	PMID:25022897|RGD:12791271
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Kif5a	IEP		Rat	PMID:8963445|RGD:12793074
Biological Process	GO:0021987	cerebral cortex development	Kif5a	IEP		Rat	PMID:9349526|RGD:12792964
Biological Process	GO:0021766	hippocampus development	Kif5a	IEP		Rat	PMID:9349526|RGD:12792964
Biological Process	GO:0048666	neuron development	Kif5a	IEP		Rat	PMID:9349526|RGD:12792964
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150211-2	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150210-17	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150210-16	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150210-15	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150211-1	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IGI	ZFIN:ZDB-GENO-150210-18	Zfish	PMID:25355224
Biological Process	GO:1990535	neuron projection maintenance	kif5aa	IMP	ZFIN:ZDB-GENO-150210-9	Zfish	PMID:25355224
Biological Process	GO:1904647	response to rotenone	Kif5a	IEP		Rat	PMID:23263842|RGD:12738403
Biological Process	GO:1990049	retrograde neuronal dense core vesicle transport	Kif5a	IGI	UniProtKB:Q2PQA9	Rat	PMID:28426968|RGD:13514087
Biological Process	GO:0021794	thalamus development	Kif5a	IEP		Rat	PMID:9349526|RGD:12792964
Biological Process	GO:0016192	vesicle-mediated transport	Kif5a	IDA		Mouse	MGI:MGI:5795817|PMID:21976701

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern