Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KITLG
  • Mouse genes Kitl
  • Rat genes Kitlg
  • Zfish genes kitlga,kitlgb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kitl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	Kitl	IDA		Mouse	PMID:12714518
Molecular Function	GO:0005515	protein binding	KITLG	IPI	UniProtKB:P10721	Human	PMID:17662946
Molecular Function	GO:0005515	protein binding	Kitl	IPI	PR:P05532	Mouse	PMID:1698557
Molecular Function	GO:0005173	stem cell factor receptor binding	Kitl	IDA		Mouse	PMID:10872802
Cellular Component	GO:0005737	cytoplasm	KITLG	IDA		Human	PMID:26522471
Cellular Component	GO:0005615	extracellular space	Kitl	IDA		Mouse	PMID:14525951
Cellular Component	GO:0005615	extracellular space	Kitl	IDA		Mouse	PMID:7690439
Cellular Component	GO:0030175	filopodium	KITLG	IDA		Human	PMID:26522471
Cellular Component	GO:0030027	lamellipodium	KITLG	IDA		Human	PMID:26522471
Cellular Component	GO:0016020	membrane	Kitl	IDA		Mouse	PMID:12140361
Cellular Component	GO:0005886	plasma membrane	KITLG	IDA		Human	PMID:26522471
Cellular Component	GO:0005886	plasma membrane	Kitl	IDA		Mouse	PMID:14525951
Biological Process	GO:0006915	apoptotic process	Kitl	IGI	MGI:MGI:99702	Mouse	PMID:17107997
Biological Process	GO:0008283	cell population proliferation	Kitl	IDA		Mouse	PMID:11435472
Biological Process	GO:0008283	cell population proliferation	Kitl	IDA		Mouse	PMID:11401406
Biological Process	GO:0008283	cell population proliferation	Kitl	IGI	MGI:MGI:96677	Mouse	PMID:10620616
Biological Process	GO:0008283	cell population proliferation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:0008283	cell population proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:10620616
Biological Process	GO:0008283	cell population proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:11401406
Biological Process	GO:0008283	cell population proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:11435472
Biological Process	GO:0035234	ectopic germ cell programmed cell death	Kitl	IMP	MGI:MGI:1856161	Mouse	PMID:17107997
Biological Process	GO:0035162	embryonic hemopoiesis	KITLG	IDA		Human	PMID:21149635
Biological Process	GO:0035162	embryonic hemopoiesis	kitlgb	IMP	ZFIN:ZDB-MRPHLNO-180920-6	Zfish	PMID:29779898
Biological Process	GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	Kitl	IDA		Mouse	PMID:15039234
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:1375116
Biological Process	GO:0061484	hematopoietic stem cell homeostasis	kitlgb	IGI	ZFIN:ZDB-GENE-041210-21	Zfish	PMID:27402973
Biological Process	GO:0008584	male gonad development	KITLG	IEP		Human	PMID:17848411
Biological Process	GO:0033024	mast cell apoptotic process	Kitl	IDA		Mouse	PMID:12714518
Biological Process	GO:0097531	mast cell migration	Kitl	IDA		Mouse	PMID:24068671
Biological Process	GO:0070662	mast cell proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:10620616
Biological Process	GO:0070662	mast cell proliferation	Kitl	IDA		Mouse	PMID:15947484
Biological Process	GO:0070662	mast cell proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:11435472
Biological Process	GO:0070662	mast cell proliferation	Kitl	IDA		Mouse	PMID:11435472
Biological Process	GO:0070662	mast cell proliferation	Kitl	IGI	MGI:MGI:96677	Mouse	PMID:10620616
Biological Process	GO:0030318	melanocyte differentiation	kitlga	IMP	ZFIN:ZDB-GENO-120316-63	Zfish	PMID:9007256
Biological Process	GO:0030318	melanocyte differentiation	kitlga	IMP	ZFIN:ZDB-GENO-120316-63	Zfish	PMID:23364329
Biological Process	GO:0030318	melanocyte differentiation	kitlga	IDA		Zfish	PMID:17257055
Biological Process	GO:0030318	melanocyte differentiation	kitlga	IGI	ZFIN:ZDB-GENO-020715-3,ZFIN:ZDB-MRPHLNO-070424-7	Zfish	PMID:17257055
Biological Process	GO:0030318	melanocyte differentiation	kitlga	IMP	ZFIN:ZDB-MRPHLNO-070424-7	Zfish	PMID:17257055
Biological Process	GO:0097324	melanocyte migration	Kitl	IDA		Mouse	PMID:11401406
Biological Process	GO:0002573	myeloid leukocyte differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:1375116
Biological Process	GO:0002573	myeloid leukocyte differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:0043066	negative regulation of apoptotic process	Kitl	IGI	MGI:MGI:99702	Mouse	PMID:17107997
Biological Process	GO:0033026	negative regulation of mast cell apoptotic process	Kitl	IDA		Mouse	PMID:12714518
Biological Process	GO:0001755	neural crest cell migration	Kitl	IDA		Mouse	PMID:11401406
Biological Process	GO:0001541	ovarian follicle development	Kitlg	IDA		Rat	PMID:15062541|RGD:1302364
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Kitl	IDA		Mouse	PMID:10872802
Biological Process	GO:0008284	positive regulation of cell population proliferation	KITLG	IDA		Human	PMID:9722506
Biological Process	GO:0008284	positive regulation of cell population proliferation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:0008284	positive regulation of cell population proliferation	Kitl	IDA		Mouse	PMID:11401406
Biological Process	GO:0008284	positive regulation of cell population proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:11401406
Biological Process	GO:0008284	positive regulation of cell population proliferation	Kitlg	IDA		Rat	PMID:2208279|RGD:1299516
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:1901534	positive regulation of hematopoietic progenitor cell differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:1375116
Biological Process	GO:1902035	positive regulation of hematopoietic stem cell proliferation	Kitl	IDA		Mouse	PMID:21540074
Biological Process	GO:0002687	positive regulation of leukocyte migration	Kitl	IDA		Mouse	PMID:24068671
Biological Process	GO:0043406	positive regulation of MAP kinase activity	Kitl	IGI	MGI:MGI:96677	Mouse	PMID:10620616
Biological Process	GO:0043406	positive regulation of MAP kinase activity	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:10620616
Biological Process	GO:0070668	positive regulation of mast cell proliferation	Kitl	IGI	MGI:MGI:96677	Mouse	PMID:10620616
Biological Process	GO:0070668	positive regulation of mast cell proliferation	Kitl	IDA		Mouse	PMID:11435472
Biological Process	GO:0070668	positive regulation of mast cell proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:11435472
Biological Process	GO:0070668	positive regulation of mast cell proliferation	Kitl	IGI	MGI:MGI:97306	Mouse	PMID:10620616
Biological Process	GO:0070668	positive regulation of mast cell proliferation	Kitl	IDA		Mouse	PMID:15947484
Biological Process	GO:0045636	positive regulation of melanocyte differentiation	Kitl	IDA		Mouse	PMID:16427619
Biological Process	GO:0002763	positive regulation of myeloid leukocyte differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:7690439
Biological Process	GO:0002763	positive regulation of myeloid leukocyte differentiation	Kitl	IGI	MGI:MGI:96552	Mouse	PMID:1375116
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Kitl	IDA		Mouse	PMID:10872802
Biological Process	GO:0046579	positive regulation of Ras protein signal transduction	Kitl	IDA		Mouse	PMID:11435472
Biological Process	GO:0042102	positive regulation of T cell proliferation	Kitl	IDA		Mouse	PMID:15947484
Biological Process	GO:0007265	Ras protein signal transduction	Kitl	IDA		Mouse	PMID:11435472
Biological Process	GO:0014070	response to organic cyclic compound	Kitlg	IEP		Rat	PMID:22777679|RGD:151893504
Biological Process	GO:0014070	response to organic cyclic compound	Kitlg	IEP		Rat	PMID:28208728|RGD:151893505
Biological Process	GO:0042098	T cell proliferation	Kitl	IDA		Mouse	PMID:15947484

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern