Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KL
  • Mouse genes Kl
  • Rat genes Kl
  • Zfish genes kl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Kl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0017134	fibroblast growth factor binding	KL	IPI	UniProtKB:O95750	Human	PMID:18829467
Molecular Function	GO:0017134	fibroblast growth factor binding	Kl	IPI	UniProtKB:Q9EPC2	Mouse	MGI:MGI:3696596|PMID:17086194
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	Kl	IPI	UniProtKB:P16092	Mouse	MGI:MGI:3696596|PMID:17086194
Molecular Function	GO:0005515	protein binding	Kl	IPI	UniProtKB:P04426|UniProtKB:P17553|UniProtKB:P22724|UniProtKB:P22725	Mouse	MGI:MGI:3718804|PMID:17690294
Molecular Function	GO:0005515	protein binding	Kl	IPI	UniProtKB:P11362|UniProtKB:P16092|UniProtKB:Q03142|UniProtKB:Q61851-1|UniProtKB:Q9GZV9	Mouse	MGI:MGI:4420739|PMID:19966287
Molecular Function	GO:0005515	protein binding	Kl	IPI	UniProtKB:P11362-7|UniProtKB:Q9GZV9	Mouse	MGI:MGI:3696596|PMID:17086194
Molecular Function	GO:0005515	protein binding	Kl	IPI	PR:Q61851	Mouse	PMID:16436388
Molecular Function	GO:0005515	protein binding	Kl	IPI	PR:Q03142	Mouse	PMID:16436388
Molecular Function	GO:0005515	protein binding	Kl	IPI	PR:P21803	Mouse	PMID:16436388
Cellular Component	GO:0070062	extracellular exosome	KL	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	KL	HDA		Human	PMID:23533145
Biological Process	GO:0002526	acute inflammatory response	Kl	IDA		Rat	PMID:9791011|RGD:633145
Biological Process	GO:0007568	aging	KL	IMP		Human	PMID:11792841
Biological Process	GO:0007568	aging	Kl	IEP		Rat	PMID:23183129|RGD:10403069
Biological Process	GO:0055074	calcium ion homeostasis	Kl	IGI	MGI:MGI:1316731	Mouse	PMID:22285620
Biological Process	GO:0008340	determination of adult lifespan	Kl	IMP	MGI:MGI:1889570	Mouse	PMID:9363890
Biological Process	GO:0040016	embryonic cleavage	kl	IMP	ZFIN:ZDB-MRPHLNO-210413-1	Zfish	PMID:32899868
Biological Process	GO:0006112	energy reserve metabolic process	Kl	IMP	MGI:MGI:1889570	Mouse	PMID:11095966
Biological Process	GO:0003085	negative regulation of systemic arterial blood pressure	Kl	IMP		Rat	PMID:20086041|RGD:10403068
Biological Process	GO:0042421	norepinephrine biosynthetic process	Kl	IMP		Rat	PMID:20086041|RGD:10403068
Biological Process	GO:0030501	positive regulation of bone mineralization	KL	IMP		Human	PMID:12110410
Biological Process	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	Kl	IGI	MGI:MGI:1891427	Mouse	PMID:16436388
Biological Process	GO:0014823	response to activity	Kl	IEP		Rat	PMID:22891896|RGD:10401895
Biological Process	GO:1990776	response to angiotensin	Kl	IEP		Rat	PMID:11967236|RGD:70544
Biological Process	GO:0071774	response to fibroblast growth factor	Kl	IEP		Rat	PMID:17992255|RGD:8554413
Biological Process	GO:0033280	response to vitamin D	Kl	IEP		Rat	PMID:20631679|RGD:10403078

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern