Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLC2
  • Mouse genes Klc2
  • Rat genes Klc2
  • Zfish genes klc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	KLC2	HDA		Human	PMID:25468996
Molecular Function	GO:0019894	kinesin binding	Klc2	IPI	UniProtKB:O70402|UniProtKB:Q61768	Mouse	MGI:MGI:1266918|PMID:9624122
Molecular Function	GO:0005515	protein binding	KLC2	IPI	UniProtKB:O14576	Human	PMID:14985359
Molecular Function	GO:0005515	protein binding	KLC2	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	KLC2	IPI	UniProtKB:Q9BQS8	Human	PMID:25855459
Molecular Function	GO:0005515	protein binding	KLC2	IPI	UniProtKB:P63104	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Klc2	IPI	UniProtKB:Q9ESN9	Mouse	MGI:MGI:2148806|PMID:11106729
Molecular Function	GO:0005515	protein binding	Klc2	IPI	UniProtKB:O94985-2|UniProtKB:Q8IWE5	Mouse	MGI:MGI:5918671|PMID:23519214
Molecular Function	GO:0005515	protein binding	Klc2	IPI	UniProtKB:P68619	Mouse	MGI:MGI:5305004|PMID:21915095
Molecular Function	GO:0005515	protein binding	Klc2	IPI	UniProtKB:Q8CII8	Mouse	MGI:MGI:4441244|PMID:19164528
Molecular Function	GO:0005515	protein binding	Klc2	IPI	UniProtKB:Q9ESN9	Mouse	MGI:MGI:5292602|PMID:21750526
Molecular Function	GO:0005515	protein binding	Klc2	IPI	PR:Q8CJ40	Mouse	PMID:16018997
Cellular Component	GO:0035253	ciliary rootlet	Klc2	IDA		Mouse	PMID:16018997
Cellular Component	GO:0035253	ciliary rootlet	Klc2	IPI	PR:Q8CJ40	Mouse	PMID:16018997
Cellular Component	GO:0005737	cytoplasm	Klc2	IDA		Mouse	PMID:16018997
Cellular Component	GO:0005829	cytosol	KLC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Klc2	IDA		Mouse	MGI:MGI:1266918|PMID:9624122
Cellular Component	GO:0005871	kinesin complex	Klc2	IDA		Mouse	MGI:MGI:1266918|PMID:9624122
Cellular Component	GO:0016020	membrane	KLC2	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	KLC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043005	neuron projection	Klc2	IDA		Mouse	PMID:16301330
Cellular Component	GO:0005654	nucleoplasm	KLC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	KLC2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032991	protein-containing complex	KLC2	IDA		Human	GO_REF:0000054
Biological Process	GO:0008088	axo-dendritic transport	Klc2	IMP		Mouse	PMID:16301330
Biological Process	GO:0032418	lysosome localization	KLC2	IMP		Human	PMID:22172677
Biological Process	GO:0036269	swimming behavior	klc2	IMP	ZFIN:ZDB-MRPHLNO-160210-5	Zfish	PMID:26385635
Biological Process	GO:0036269	swimming behavior	klc2	IMP	ZFIN:ZDB-MRPHLNO-160210-6	Zfish	PMID:26385635
Biological Process	GO:0006590	thyroid hormone generation	klc2	IMP	ZFIN:ZDB-MRPHLNO-160210-6	Zfish	PMID:33912899

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern