Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLF10
  • Mouse genes Klf10
  • Rat genes Klf10
  • Zfish genes klf10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klf10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001046	core promoter sequence-specific DNA binding	Klf10	IDA		Mouse	MGI:MGI:4438787|PMID:20070857
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	KLF10	IDA		Human	PMID:15087465
Molecular Function	GO:0005515	protein binding	KLF10	IPI	UniProtKB:P08047	Human	PMID:10976766
Molecular Function	GO:0005515	protein binding	Klf10	IPI	UniProtKB:Q8C863	Mouse	MGI:MGI:3775527|PMID:18278048
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	KLF10	IDA		Human	PMID:15087465
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	KLF10	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Klf10	IDA		Mouse	MGI:MGI:4438787|PMID:20070857
Cellular Component	GO:0005634	nucleus	Klf10	IDA		Rat	PMID:20070857|RGD:10047352
Biological Process	GO:0030282	bone mineralization	Klf10	IMP	MGI:MGI:3530069	Mouse	PMID:15657444
Biological Process	GO:1901653	cellular response to peptide	Klf10	IEP		Rat	PMID:18406357|RGD:2316543
Biological Process	GO:0009267	cellular response to starvation	Klf10	IDA		Mouse	MGI:MGI:4438787|PMID:20070857
Biological Process	GO:0007623	circadian rhythm	Klf10	IEP		Mouse	MGI:MGI:4438787|PMID:20070857
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Klf10	IDA		Mouse	MGI:MGI:4438787|PMID:20070857
Biological Process	GO:0045672	positive regulation of osteoclast differentiation	Klf10	IMP	MGI:MGI:3530069	Mouse	PMID:15657444
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	KLF10	IDA		Human	PMID:15087465
Biological Process	GO:0042752	regulation of circadian rhythm	Klf10	IMP		Rat	PMID:20070857|RGD:10047352
Biological Process	GO:0006355	regulation of DNA-templated transcription	Klf10	IMP	MGI:MGI:3530069	Mouse	PMID:15657444
Biological Process	GO:0035019	somatic stem cell population maintenance	Klf10	IDA		Mouse	PMID:19379700

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern