Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLF15
  • Mouse genes Klf15
  • Rat genes Klf15
  • Zfish genes klf15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klf15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Klf15	IDA		Mouse	PMID:12097321
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	KLF15	IMP		Human	PMID:19767294
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Klf15	IDA		Mouse	PMID:12097321
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q09472	Human	PMID:23999430
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43741	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43167	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43741	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43167	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43741	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43167	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43741	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O15160	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43167	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O43741	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P36508	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P52597	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q13952-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q16656-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q2TAC2-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q8N9N5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q8WVZ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q92997	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9BWG6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9H3H3-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9NUL5-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9Y3S2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:D3DTS7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O60260-5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O60333-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P01100	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P04792	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P12931	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P31153	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P37840	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P42261	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P62491	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:P62993	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q00403	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q00613	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q01658	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q13148	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q8N2W9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q96A83-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9Y3C5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	KLF15	IPI	UniProtKB:Q9Y5Q9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Klf15	IPI	PR:Q60929	Mouse	PMID:12097321
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	KLF15	IDA		Human	PMID:19767294
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	KLF15	IDA		Human	PMID:19767294
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	KLF15	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Klf15	IDA		Mouse	MGI:MGI:5312158|PMID:22367544
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	KLF15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	KLF15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	KLF15	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	KLF15	IDA		Human	PMID:17438289
Cellular Component	GO:0005634	nucleus	Klf15	IDA		Mouse	PMID:12097321
Biological Process	GO:0014898	cardiac muscle hypertrophy in response to stress	Klf15	IMP		Mouse	MGI:MGI:3709247|PMID:17438289
Biological Process	GO:1901653	cellular response to peptide	Klf15	IEP		Rat	PMID:18406357|RGD:2316543
Biological Process	GO:0010001	glial cell differentiation	Klf15	IDA		Mouse	PMID:19741146
Biological Process	GO:0001678	intracellular glucose homeostasis	Klf15	IDA		Mouse	PMID:12097321
Biological Process	GO:2000757	negative regulation of peptidyl-lysine acetylation	KLF15	IMP		Human	PMID:20375365
Biological Process	GO:2000757	negative regulation of peptidyl-lysine acetylation	Klf15	IMP		Mouse	MGI:MGI:4880843|PMID:20375365
Biological Process	GO:0072112	podocyte differentiation	Klf15	IMP		Mouse	MGI:MGI:5431194|PMID:22493483
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Klf15	IDA		Mouse	PMID:12097321
Biological Process	GO:0046326	positive regulation of glucose import	Klf15	IDA		Mouse	PMID:12097321
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	KLF15	IMP		Human	PMID:19767294
Biological Process	GO:0010468	regulation of gene expression	Klf15	IMP		Mouse	MGI:MGI:3709247|PMID:17438289
Biological Process	GO:0010468	regulation of gene expression	Klf15	IMP		Mouse	PMID:31582141
Biological Process	GO:0030111	regulation of Wnt signaling pathway	Klf15	IMP		Mouse	PMID:31582141
Biological Process	GO:0032868	response to insulin	Klf15	IDA		Mouse	PMID:12097321

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern