Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes KLF16
  • Mouse genes Klf16
  • Rat genes Klf16
  • Zfish genes zgc:153115
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Klf16

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Klf16	IDA		Mouse	PMID:11390978
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Klf16	IDA		Mouse	PMID:11390978
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Klf16	IDA		Mouse	MGI:MGI:2153043|PMID:11390978
Molecular Function	GO:0005515	protein binding	KLF16	IPI	UniProtKB:Q8WUI4-6	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Klf16	IDA		Mouse	MGI:MGI:2153043|PMID:11390978
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	KLF16	IDA		Human	PMID:28473536
Biological Process	GO:0006351	DNA-templated transcription	Klf16	IDA		Mouse	MGI:MGI:2153043|PMID:11390978
Biological Process	GO:0007212	dopamine receptor signaling pathway	Klf16	IDA		Mouse	PMID:11390978
Biological Process	GO:0031018	endocrine pancreas development	zgc:153115	IMP	ZFIN:ZDB-MRPHLNO-161208-3	Zfish	PMID:26963759
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Klf16	IDA		Mouse	MGI:MGI:2153043|PMID:11390978
Biological Process	GO:0006355	regulation of DNA-templated transcription	Klf16	IDA		Mouse	MGI:MGI:2153043|PMID:11390978
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Klf16	IDA		Mouse	PMID:11390978

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern